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4XL3
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Crystal structure of reduced form of thiolase from Clostridium acetobutylicum
Descriptor: Acetyl-CoA acetyltransferase, GLYCEROL
Authors:Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
Deposit date:2015-01-13
Release date:2015-10-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
6PCD
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BU of 6pcd by Molmil
Crystal structure of beta-ketoadipyl-CoA thiolase mutant (C90S-H356A) in complex Octanoyl coenzyme A
Descriptor: Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, COENZYME A, ...
Authors:Sukritee, B, Panjikar, S.
Deposit date:2019-06-17
Release date:2020-05-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
4O99
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Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase, GLYCEROL
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2014-12-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
4NZS
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BU of 4nzs by Molmil
Crystal structure of beta-ketothiolase BktB B from Ralstonia eutropha H16
Descriptor: Beta-ketothiolase BktB
Authors:Kim, E.J, Son, H, Kim, S, Kim, K.J.
Deposit date:2013-12-12
Release date:2014-11-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure and biochemical characterization of beta-keto thiolase B from polyhydroxyalkanoate-producing bacterium Ralstonia eutropha H16
Biochem.Biophys.Res.Commun., 444, 2014
4UBV
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BU of 4ubv by Molmil
Structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis with an partially acetylated cysteine in complex with acetyl-CoA and CoA
Descriptor: 1,4-DIETHYLENE DIOXIDE, ACETYL COENZYME *A, Acetyl-CoA acetyltransferase FadA5, ...
Authors:Schaefer, C.M, Kisker, C.
Deposit date:2014-08-13
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.
Structure, 23, 2015
4O9C
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BU of 4o9c by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase, COENZYME A
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2014-12-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
4UBT
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Structure of the C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with a steroid and CoA.
Descriptor: (2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoic acid (non-preferred name), Acetyl-CoA acetyltransferase FadA5, CHLORIDE ION, ...
Authors:Schaefer, C.M, Kisker, C.
Deposit date:2014-08-13
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.
Structure, 23, 2015
4UBU
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BU of 4ubu by Molmil
Structure of a modified C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with CoA
Descriptor: Acetyl-CoA acetyltransferase FadA5, COENZYME A, GLYCEROL
Authors:Schaefer, C.M, Kisker, C.
Deposit date:2014-08-13
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.
Structure, 23, 2015
4UBW
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BU of 4ubw by Molmil
Apo structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis
Descriptor: Acetyl-CoA acetyltransferase FadA5, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Schaefer, C.M, Kisker, C.
Deposit date:2014-08-13
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.
Structure, 23, 2015
4ZRC
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BU of 4zrc by Molmil
Crystal structure of MSM-13, a putative T1-like thiolase from Mycobacterium smegmatis
Descriptor: Beta-ketothiolase
Authors:Janardan, N, Harijan, R.K, Keima, T.R, Wierenga, R, Murthy, M.R.N.
Deposit date:2015-05-12
Release date:2016-05-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural characterization of a mitochondrial 3-ketoacyl-CoA (T1)-like thiolase from Mycobacterium smegmatis
Acta Crystallogr.,Sect.D, 71, 2015
4O9A
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BU of 4o9a by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2015-02-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
2F2S
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BU of 2f2s by Molmil
Human mitochondrial acetoacetyl-CoA thiolase
Descriptor: Acetyl-CoA acetyltransferase, mitochondrial, CHLORIDE ION, ...
Authors:Min, J.R, Dombrovski, L, Antoshenko, T, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-11-17
Release date:2005-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Mitochondrial Acetoacetyl-Coa Thiolase Acat1.
To be Published
2D3T
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BU of 2d3t by Molmil
Fatty Acid beta-oxidation multienzyme complex from Pseudomonas Fragi, Form V
Descriptor: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
Authors:Tsuchiya, D, Shimizu, N, Ishikawa, M, Suzuki, Y, Morikawa, K.
Deposit date:2005-10-01
Release date:2006-02-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ligand-Induced Domain Rearrangement of Fatty Acid beta-Oxidation Multienzyme Complex
Structure, 14, 2006
1WDL
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BU of 1wdl by Molmil
fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4)
Descriptor: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ...
Authors:Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
Deposit date:2004-05-17
Release date:2004-07-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
1WDK
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BU of 1wdk by Molmil
fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)
Descriptor: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ...
Authors:Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
Deposit date:2004-05-17
Release date:2004-07-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
1WDM
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BU of 1wdm by Molmil
fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3)
Descriptor: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
Authors:Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
Deposit date:2004-05-17
Release date:2004-07-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
1WL4
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BU of 1wl4 by Molmil
Human cytosolic acetoacetyl-CoA thiolase complexed with CoA
Descriptor: COENZYME A, GLYCEROL, SULFATE ION, ...
Authors:Kursula, P, Fukao, T, Kondo, N, Wierenga, R.K.
Deposit date:2004-06-20
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:High Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I
J.Mol.Biol., 347, 2005
1WL5
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BU of 1wl5 by Molmil
Human cytosolic acetoacetyl-CoA thiolase
Descriptor: GLYCEROL, SULFATE ION, acetyl-Coenzyme A acetyltransferase 2
Authors:Kursula, P, Fukao, T, Kondo, N, Wierenga, R.K.
Deposit date:2004-06-20
Release date:2005-03-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:High Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I
J.Mol.Biol., 347, 2005
4C2K
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BU of 4c2k by Molmil
Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Kiema, T.-R, Harijan, R.K, Wierenga, R.K.
Deposit date:2013-08-19
Release date:2014-09-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D, 70, 2014
4B3H
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BU of 4b3h by Molmil
Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex
Descriptor: FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB, FATTY ACID BETA-OXIDATION COMPLEX BETA-CHAIN FADA, GLYCEROL, ...
Authors:Venkatesan, R, Wierenga, R.
Deposit date:2012-07-24
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Mycobacterial Beta-Oxidation Trifunctional Enzyme Reveals its Altered Assembly and Putative Substrate Channeling Pathway.
Acs Chem.Biol., 8, 2013
4C2J
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BU of 4c2j by Molmil
Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase in complex with CoA
Descriptor: 1,2-ETHANEDIOL, 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL, ...
Authors:Kiema, T.-R, Harijan, R.K, Wierenga, R.K.
Deposit date:2013-08-19
Release date:2014-09-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D, 70, 2014
4B3J
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BU of 4b3j by Molmil
Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA bound at the hydratase and thiolase active sites
Descriptor: ADENOSINE-5'-DIPHOSPHATE, COENZYME A, FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB, ...
Authors:Venkatesan, R, Wierenga, R.K.
Deposit date:2012-07-24
Release date:2013-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mycobacterial Beta-Oxidation Trifunctional Enzyme Reveals its Altered Assembly and Putative Substrate Channeling Pathway.
Acs Chem.Biol., 8, 2013
4B3I
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BU of 4b3i by Molmil
Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA bound at the hydratase active sites
Descriptor: ADENOSINE-5'-DIPHOSPHATE, COENZYME A, FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB, ...
Authors:Venkatesan, R, Wierenga, R.K.
Deposit date:2012-07-24
Release date:2013-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structure of Mycobacterial Beta-Oxidation Trifunctional Enzyme Reveals its Altered Assembly and Putative Substrate Channeling Pathway.
Acs Chem.Biol., 8, 2013
4DD5
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BU of 4dd5 by Molmil
Biosynthetic Thiolase (ThlA1) from Clostridium difficile
Descriptor: Acetyl-CoA acetyltransferase
Authors:Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-01-18
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Biosynthetic Thiolase (ThlA1) from Clostridium difficile
To be Published
2IIK
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BU of 2iik by Molmil
Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
Descriptor: 3-ketoacyl-CoA thiolase, peroxisomal
Authors:Papagrigoriou, E, Johansson, C, Smee, C, Kavanagh, K, Pike, A.C.W, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C.H, Gileadi, O, Gorrec, F, Umeano, C, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-09-28
Release date:2006-10-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
TO BE PUBLISHED

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