PDB: 131 resultsInfo pagesStatus searchChemie searchBIRD

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2GPW	Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli. Descriptor: Biotin carboxylase Authors: Shen, Y, Chou, C.Y, Chang, G.G, Tong, L. Deposit date: 2006-04-18 Release date: 2006-07-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006
5DOT	Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), apo form Descriptor: 1,2-ETHANEDIOL, Carbamoyl-phosphate synthase [ammonia], mitochondrial, ... Authors: Polo, L.M, de Cima, S, Fita, I, Rubio, V. Deposit date: 2015-09-11 Release date: 2015-12-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. Sci Rep, 5, 2015
2V59	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2 Descriptor: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V58	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 Descriptor: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 Descriptor: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.31 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2HJW	Crystal Structure of the BC domain of ACC2 Descriptor: Acetyl-CoA carboxylase 2 Authors: Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. Deposit date: 2006-07-02 Release date: 2007-07-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2. Proteins, 70, 2008
4HR7	Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli Descriptor: 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ... Authors: Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L. Deposit date: 2012-10-26 Release date: 2013-03-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.495 Å) Cite: The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase. Structure, 21, 2013
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment Descriptor: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2VQD	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP Descriptor: BIOTIN CARBOXYLASE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... Authors: Mochalkin, I. Deposit date: 2008-03-13 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2W6O	Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment Descriptor: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
4HNU	crystal structure of K442E mutant of S. aureus Pyruvate carboxylase Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Yu, L.P.C, Tong, L. Deposit date: 2012-10-21 Release date: 2013-01-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3 Å) Cite: Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis. Biochemistry, 52, 2013
4HQ6	BC domain in the presence of citrate Descriptor: Acetyl-CoA carboxylase 2 Authors: Heo, Y.S. Deposit date: 2012-10-25 Release date: 2013-10-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural Insights into the Regulation of ACC2 by Citrate Bull.Korean Chem.Soc., 34, 2013
4HNV	Crystal structure of R54E mutant of S. aureus Pyruvate carboxylase Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Yu, L.P.C, Tong, L. Deposit date: 2012-10-21 Release date: 2013-01-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis. Biochemistry, 52, 2013
3U9T	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme Descriptor: Methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit Authors: Huang, C.S, Tong, L. Deposit date: 2011-10-19 Release date: 2011-12-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012
4HNT	crystal structure of F403A mutant of S. aureus Pyruvate carboxylase Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Yu, L.P.C, Tong, L. Deposit date: 2012-10-21 Release date: 2013-01-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis. Biochemistry, 52, 2013
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine Descriptor: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6M	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Descriptor: (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
3OUZ	Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, D-MALATE, ... Authors: Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2010-09-15 Release date: 2010-10-13 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.902 Å) Cite: Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni TO BE PUBLISHED
3VA7	Crystal structure of the Kluyveromyces lactis Urea Carboxylase Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, GLYCEROL, KLLA0E08119p, ... Authors: Fan, C, Xiang, S. Deposit date: 2011-12-29 Release date: 2012-02-01 Last modified: 2013-07-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction J.Biol.Chem., 287, 2012
3OUU	Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex from Campylobacter jejuni Descriptor: Biotin carboxylase, CACODYLATE ION, CALCIUM ION, ... Authors: Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2010-09-15 Release date: 2010-10-20 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.252 Å) Cite: Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex from Campylobacter jejuni TO BE PUBLISHED
3TW6	Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: St Maurice, M, Kumar, S, Lietzan, A.D. Deposit date: 2011-09-21 Release date: 2011-10-19 Last modified: 2011-12-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
3TW7	Structure of Rhizobium etli pyruvate carboxylase T882A crystallized without acetyl coenzyme-A Descriptor: CHLORIDE ION, MAGNESIUM ION, Pyruvate carboxylase protein, ... Authors: St Maurice, M, Kumar, S, Lietzan, A.D. Deposit date: 2011-09-21 Release date: 2011-10-12 Last modified: 2011-12-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
3U9S	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Methylcrotonyl-CoA carboxylase, ... Authors: Huang, C.S, Tong, L. Deposit date: 2011-10-19 Release date: 2011-12-14 Last modified: 2013-01-23 Method: X-RAY DIFFRACTION (3.5 Å) Cite: An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012
3RUP	Crystal structure of E.coli biotin carboxylase in complex with two ADP and two Ca ions Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, CALCIUM ION, ... Authors: Chou, C.Y, Tong, L. Deposit date: 2011-05-05 Release date: 2011-05-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
3RV4	Crystal structure of E.coli biotin carboxylase R16E mutant in complex with Mg-ADP and bicarbonate Descriptor: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, Biotin carboxylase, ... Authors: Chou, C.Y, Tong, L. Deposit date: 2011-05-05 Release date: 2011-05-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011

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