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1SYQ
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BU of 1syq by Molmil
Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636
Descriptor: Talin 1, vinculin isoform VCL
Authors:Izard, T, Vonrhein, C.
Deposit date:2004-04-01
Release date:2004-07-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for amplifying vinculin activation by talin
J.Biol.Chem., 279, 2004
1YDI
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BU of 1ydi by Molmil
Human Vinculin Head Domain (VH1, 1-258) in Complex with Human Alpha-Actinin's Vinculin-Binding Site (Residues 731-760)
Descriptor: Alpha-actinin 4, vinculin isoform VCL
Authors:Izard, T.
Deposit date:2004-12-23
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Dynamics of {alpha}-Actinin-Vinculin Interactions.
Mol.Cell.Biol., 14, 2005
2GDC
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BU of 2gdc by Molmil
Structure of Vinculin VD1 / IpaA560-633 complex
Descriptor: Invasin ipaA, Vinculin
Authors:Hamiaux, C, van Eerde, A, Parsot, C, Broos, J, Dijkstra, B.W.
Deposit date:2006-03-15
Release date:2006-08-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri.
Embo Rep., 7, 2006
2HSQ
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BU of 2hsq by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)
Descriptor: Invasin ipaA, Vinculin
Authors:Izard, T.
Deposit date:2006-07-22
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.97 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
2IBF
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BU of 2ibf by Molmil
Human vinculin's head domain (Vh1, residues 1-258) in complex with two vinculin binding sites of Shigella flexneri's IpaA (residues 565-587)
Descriptor: Invasin ipaA, Vinculin
Authors:Izard, T.
Deposit date:2006-09-11
Release date:2007-09-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Vinculin binding in its closed conformation by a helix addition mechanism.
Embo J., 26, 2007
2GWW
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BU of 2gww by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site (residues 602-633)
Descriptor: IpaA, vinculin
Authors:Izard, T.
Deposit date:2006-05-07
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
3RF3
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BU of 3rf3 by Molmil
Shigella IpaA-VBS3 in complex with human vinculin
Descriptor: CACODYLATE ION, Invasin ipaA, Vinculin
Authors:Park, H, Sharff, A, Izard, T.
Deposit date:2011-04-05
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011
9DVA
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BU of 9dva by Molmil
F-actin binding interface of alpha-E-catenin ABD (cadherin-catenin complex) and afadin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gong, R, Reynolds, M.J, Alushin, G.M.
Deposit date:2024-10-07
Release date:2024-10-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature.
Biorxiv, 2024
7UTJ
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BU of 7utj by Molmil
Cryogenic electron microscopy 3D map of F-actin bound by human dimeric alpha-catenin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rangarajan, E.S, Smith, E.W, Izard, T.
Deposit date:2022-04-27
Release date:2023-03-08
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Distinct inter-domain interactions of dimeric versus monomeric alpha-catenin link cell junctions to filaments.
Commun Biol, 6, 2023
3H2V
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BU of 3h2v by Molmil
Human raver1 RRM1 domain in complex with human vinculin tail domain Vt
Descriptor: Raver-1, Vinculin
Authors:Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
Deposit date:2009-04-14
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
3VF0
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BU of 3vf0 by Molmil
Raver1 in complex with metavinculin L954 deletion mutant
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ribonucleoprotein PTB-binding 1, ...
Authors:Lee, J.H, Vonrhein, C, Bricogne, G, Izard, T.
Deposit date:2012-01-09
Release date:2012-07-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The Metavinculin Tail Domain Directs Constitutive Interactions with Raver1 and vinculin RNA.
J.Mol.Biol., 422, 2012
6UPW
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BU of 6upw by Molmil
Metavinculin ABD-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Alushin, G.M.
Deposit date:2019-10-18
Release date:2020-09-30
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
6UPV
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BU of 6upv by Molmil
Alpha-E-catenin ABD-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Alushin, G.M.
Deposit date:2019-10-18
Release date:2020-09-30
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
3JBK
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BU of 3jbk by Molmil
Cryo-EM reconstruction of the metavinculin-actin interface
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M.
Deposit date:2015-09-03
Release date:2015-11-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:The Structural Basis of Actin Organization by Vinculin and Metavinculin.
J.Mol.Biol., 428, 2016
3JBI
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BU of 3jbi by Molmil
MDFF model of the vinculin tail domain bound to F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M.
Deposit date:2015-09-02
Release date:2015-11-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:The Structural Basis of Actin Organization by Vinculin and Metavinculin.
J.Mol.Biol., 428, 2016
3H2U
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BU of 3h2u by Molmil
Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt
Descriptor: Raver-1, Vinculin
Authors:Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
Deposit date:2009-04-14
Release date:2009-07-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
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