PDB: 202 resultsInfo pagesStatus searchChemie searchBIRD

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6TZ3	Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ Descriptor: SULFATE ION, Synaptotagmin-1 Authors: Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B. Deposit date: 2019-08-09 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
6U41	1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) Descriptor: SULFATE ION, Synaptotagmin-1 Authors: Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. Deposit date: 2019-08-22 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
3N5A	Synaptotagmin-7, C2B-domain, calcium bound Descriptor: CALCIUM ION, Synaptotagmin-7 Authors: Tomchick, D.R, Rizo, J, Craig, T.K. Deposit date: 2010-05-24 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.441 Å) Cite: Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One, 5, 2010
3PYC	Crystal structure of human SMURF1 C2 domain Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase SMURF1, SULFATE ION Authors: Li, X, Li, P. Deposit date: 2010-12-13 Release date: 2011-04-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Crystal structure of human SMURF1 C2 domain To be Published
5A52	The crystal structure of Arabidopsis thaliana CAR1 in complex with one calcium ion Descriptor: CALCIUM ION, CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN, GLYCEROL, ... Authors: Fernandez, D, Marquez, J.A. Deposit date: 2015-06-16 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
5VFE	Synaptotagmin 1 C2A domain, lead-bound Descriptor: LEAD (II) ION, SULFATE ION, Synaptotagmin-1 Authors: Taylor, A.B, Hart, P.J, Igumenova, T.I. Deposit date: 2017-04-07 Release date: 2018-04-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.38 Å) Cite: High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
5A4X	The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions and Zn Descriptor: AT3G17980, CALCIUM ION, ZINC ION Authors: Diaz, M, Albert, A. Deposit date: 2015-06-15 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
5A50	The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions, Zn and Phopho Choline Descriptor: AT3G17980, CALCIUM ION, PHOSPHOCHOLINE, ... Authors: Diaz, M, Albert, A. Deposit date: 2015-06-16 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
1RH8	Three-dimensional structure of the calcium-free Piccolo C2A-domain Descriptor: Piccolo protein Authors: Garcia, J, Gerber, S.H, Sugita, S, Sudhof, T.C, Rizo, J. Deposit date: 2003-11-14 Release date: 2004-01-13 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: A conformational switch in the Piccolo C2A domain regulated by alternative splicing. Nat.Struct.Mol.Biol., 11, 2004
1RLW	CALCIUM-PHOSPHOLIPID BINDING DOMAIN FROM CYTOSOLIC PHOSPHOLIPASE A2 Descriptor: CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE A2 Authors: Perisic, O, Williams, R.L. Deposit date: 1997-10-28 Release date: 1998-02-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2. J.Biol.Chem., 273, 1998
4ICX	N-terminal C2 domain of human CEP120 Descriptor: Centrosomal protein of 120 kDa Authors: Janowski, R, Guarin, N, Coll, M. Deposit date: 2012-12-11 Release date: 2014-06-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: N-terminal C2 domain tandem of human CEP120 shows lipid binding properties To be Published
4ICW	N-terminal C2 domain of human CEP120 Descriptor: Centrosomal protein of 120 kDa Authors: Janowski, R, Guarin, N, Coll, M. Deposit date: 2012-12-11 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: N-terminal C2 domain tandem of human CEP120 shows lipid binding properties To be Published
1RSY	STRUCTURE OF THE FIRST C2-DOMAIN OF SYNAPTOTAGMIN I: A NOVEL CA2+(SLASH)PHOSPHOLIPID BINDING FOLD Descriptor: SULFATE ION, SYNAPTOTAGMIN I Authors: Sutton, R.B, Sprang, S.R. Deposit date: 1995-02-01 Release date: 1995-05-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold. Cell(Cambridge,Mass.), 80, 1995
6ANJ	Synaptotagmin-7, C2A domain Descriptor: ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... Authors: Tomchick, D.R, Rizo, J, Voleti, R. Deposit date: 2017-08-13 Release date: 2017-09-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.698 Å) Cite: Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ANK	Synaptotagmin-7, C2A- and C2B-domains Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 Authors: Tomchick, D.R, Rizo, J, Voleti, R. Deposit date: 2017-08-13 Release date: 2017-09-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.254 Å) Cite: Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2NQ3	Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase Descriptor: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase Authors: Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2006-10-30 Release date: 2006-11-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase To be Published
2NCE	Solution Structure of Ca2+-bound C2 domain from Protein Kinase C alpha in the form of complex with V5-pHM peptide Descriptor: CALCIUM ION, Protein kinase C alpha type Authors: Yang, Y, Igumenova, T.I. Deposit date: 2016-03-28 Release date: 2017-03-29 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Ca2+-sensing domain contributes to auto-inhibition of protein kinase Calpha through interactions with C-terminal tail To be Published
6BTY	Crystal structure of the PI3KC2alpha C2 domain in space group P41212 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Authors: Chen, K.-E, Collins, B.M. Deposit date: 2017-12-08 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.678 Å) Cite: Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
2NSQ	Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL Authors: Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2006-11-06 Release date: 2006-12-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein To be Published
6BU0	Crystal structure of the PI3KC2alpha C2 domain in complex with IP6 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... Authors: Chen, K.-E, Collins, B.M. Deposit date: 2017-12-08 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.427 Å) Cite: Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
6CXW	Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function Descriptor: Synaptotagmin 1 C2A beta4 chimera Authors: Sutton, R.B. Deposit date: 2018-04-04 Release date: 2019-04-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.832 Å) Cite: Engineering a C2-domain to bind PIP2 To Be Published
6BTZ	Crystal structure of the PI3KC2alpha C2 domain in space group C121 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ... Authors: Chen, K.-E, Collins, B.M. Deposit date: 2017-12-08 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
2Q3X	The RIM1alpha C2B domain Descriptor: CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ... Authors: Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J. Deposit date: 2007-05-30 Release date: 2007-08-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution. Biochemistry, 46, 2007
4RJ9	Structure of a plant specific C2 domain protein, OsGAP1 from rice Descriptor: C2 domain-containing protein-like, POTASSIUM ION Authors: Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. Deposit date: 2014-10-08 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). J.Biol.Chem., 290, 2015
1A25	C2 DOMAIN FROM PROTEIN KINASE C (BETA) Descriptor: CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA) Authors: Sutton, R.B, Sprang, S.R. Deposit date: 1998-01-16 Release date: 1998-05-06 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+. Structure, 6, 1998

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