7SAP
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![BU of 7sap by Molmil](/molmil-images/mine/7sap) | The CTI-homolog pacifastin | Descriptor: | GLYCEROL, Serine protease inhibitor I/II-like Protein | Authors: | Gewe, M.M, Strong, R.K. | Deposit date: | 2021-09-23 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
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7SGQ
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7SLT
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![BU of 7slt by Molmil](/molmil-images/mine/7slt) | |
7SAO
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![BU of 7sao by Molmil](/molmil-images/mine/7sao) | The CTI-homolog pacifastin | Descriptor: | COBALT (II) ION, Pacifastin | Authors: | Gewe, M.M, Strong, R.K. | Deposit date: | 2021-09-23 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
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7SND
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![BU of 7snd by Molmil](/molmil-images/mine/7snd) | Pacifastin related protease inhibitors | Descriptor: | GLYCEROL, PHOSPHATE ION, Pacifastin-related peptide | Authors: | Gewe, M.M, Strong, R.K. | Deposit date: | 2021-10-27 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
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7SNC
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![BU of 7snc by Molmil](/molmil-images/mine/7snc) | Pacifastin related protease inhibitors | Descriptor: | Protease inhibitor | Authors: | Gewe, M.M, Strong, R.K. | Deposit date: | 2021-10-27 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
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7UE9
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![BU of 7ue9 by Molmil](/molmil-images/mine/7ue9) | Structure of anti-C3d Fab(3d8b) in complex with C3d | Descriptor: | Complement C3dg fragment, Fab heavy chain, Fab light chain, ... | Authors: | Olland, A.M, White, A, Suto, R.K. | Deposit date: | 2022-03-21 | Release date: | 2022-06-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue. Front Immunol, 13, 2022
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6DGK
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6DWZ
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![BU of 6dwz by Molmil](/molmil-images/mine/6dwz) | Hermes transposase deletion dimer complex with (C/G) DNA | Descriptor: | DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ... | Authors: | Dyda, F, Hickman, A.B. | Deposit date: | 2018-06-28 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. Nucleic Acids Res., 46, 2018
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6DSI
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7Q1Z
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![BU of 7q1z by Molmil](/molmil-images/mine/7q1z) | Structure of formaldehyde cross-linked SARS-CoV-2 S glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Sulbaran, G, Effantin, G, Schoehn, G, Weissenhorn, W. | Deposit date: | 2021-10-22 | Release date: | 2022-03-09 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects macaques from infection. Cell Rep Med, 3, 2022
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6DKB
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![BU of 6dkb by Molmil](/molmil-images/mine/6dkb) | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10b. | Descriptor: | 2-{[(3R,4S)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1H-imidazol-4-yl)pyridine-3-carboxamide, High affinity nerve growth factor receptor | Authors: | Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. | Deposit date: | 2018-05-29 | Release date: | 2018-07-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. J. Med. Chem., 61, 2018
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6DKI
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![BU of 6dki by Molmil](/molmil-images/mine/6dki) | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 19. | Descriptor: | 5-phenylthieno[2,3-d]pyrimidin-4(3H)-one, 6-amino-5-{[(3S)-4,4-difluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}pyrrolidin-3-yl]oxy}-N-methylpyridine-3-carboxamide, High affinity nerve growth factor receptor | Authors: | Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. | Deposit date: | 2018-05-29 | Release date: | 2018-07-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. J. Med. Chem., 61, 2018
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6DWW
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![BU of 6dww by Molmil](/molmil-images/mine/6dww) | Hermes transposase deletion dimer complex with (A/T) DNA and Mn2+ | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ... | Authors: | Dyda, F, Voth, A.R, Hickman, A.B. | Deposit date: | 2018-06-28 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.851 Å) | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. Nucleic Acids Res., 46, 2018
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6DKG
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![BU of 6dkg by Molmil](/molmil-images/mine/6dkg) | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 13b. | Descriptor: | 2-{[(3R,4S)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-4-(2-hydroxy-2-methylpropoxy)benzamide, 5-phenylthieno[2,3-d]pyrimidin-4(3H)-one, High affinity nerve growth factor receptor | Authors: | Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. | Deposit date: | 2018-05-29 | Release date: | 2018-07-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. J. Med. Chem., 61, 2018
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6DX0
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![BU of 6dx0 by Molmil](/molmil-images/mine/6dx0) | Hermes transposase deletion dimer complex with (A/T) DNA | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ... | Authors: | Dyda, F, Voth, A.R, Hickman, A.B. | Deposit date: | 2018-06-28 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. Nucleic Acids Res., 46, 2018
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6DKW
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6DWY
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![BU of 6dwy by Molmil](/molmil-images/mine/6dwy) | Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+ | Descriptor: | CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ... | Authors: | Dyda, F, Hickman, A.B. | Deposit date: | 2018-06-28 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. Nucleic Acids Res., 46, 2018
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2JRV
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![BU of 2jrv by Molmil](/molmil-images/mine/2jrv) | The third dimensional structure of mab198-bound pep.1 for autoimmune myasthenia gravis | Descriptor: | PEPTIDE PEP.1 | Authors: | Jung, H.H, Yi, H.J, Lee, S.K, Lee, J.Y, Jung, H.J, Yang, S.T, Eu, Y.-J, Im, S.-H, Kim, J.I. | Deposit date: | 2007-06-29 | Release date: | 2008-07-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis Biochemistry, 46, 2007
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6DYX
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6E18
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![BU of 6e18 by Molmil](/molmil-images/mine/6e18) | Crystal structure of Chlamydomonas reinhardtii HAP2 ectodomain provides structural insights of functional loops in green algae. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Baquero, E, Legrand, P, Rey, F.A. | Deposit date: | 2018-07-09 | Release date: | 2018-11-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies. Structure, 27, 2019
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2JRW
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![BU of 2jrw by Molmil](/molmil-images/mine/2jrw) | Solution structure of Cyclic extended Pep1(Cyc.ext.Pep.1) for autoimmune myasthenia gravis | Descriptor: | Cyclic extended Pep.1 | Authors: | Jung, H.H, Yi, H.J, Lee, S.K, Lee, J.Y, Jung, H.J, Yang, S.T, Eu, Y.-J, Im, S.-H, Kim, J.I. | Deposit date: | 2007-06-29 | Release date: | 2008-07-01 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis Biochemistry, 46, 2007
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7PGF
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7PGG
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![BU of 7pgg by Molmil](/molmil-images/mine/7pgg) | NaVAb1p detergent (DM) | Descriptor: | 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-13 | Release date: | 2022-06-15 | Last modified: | 2022-06-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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6ZDX
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![BU of 6zdx by Molmil](/molmil-images/mine/6zdx) | RIFIN variable region bound to LILRB1 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... | Authors: | Harrison, T.E, Higgins, M.K. | Deposit date: | 2020-06-15 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for RIFIN-mediated activation of LILRB1 in malaria. Nature, 587, 2020
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