5K1H
 
 | | eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation. | | Descriptor: | Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail | | Authors: | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | | Deposit date: | 2016-05-18 | | Release date: | 2016-07-13 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
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5LSL
 | | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | | Descriptor: | Cold sensitive U2 snRNA suppressor 1, Protein HSH49 | | Authors: | van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K. | | Deposit date: | 2016-09-02 | | Release date: | 2017-04-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
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5LXR
 | | Structure of the minimal RBM7 - ZCCHC8 Complex | | Descriptor: | BROMIDE ION, CHLORIDE ION, RNA-binding protein 7, ... | | Authors: | Falk, S, Finogenova, K, Benda, C, Conti, E. | | Deposit date: | 2016-09-22 | | Release date: | 2016-12-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
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5LXY
 | | Structure of the minimal RBM7 - ZCCHC8 Complex | | Descriptor: | BROMIDE ION, RNA-binding protein 7, Zinc finger CCHC domain-containing protein 8 | | Authors: | Falk, S, Finogenova, K, Benda, C, Conti, E. | | Deposit date: | 2016-09-23 | | Release date: | 2016-12-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
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3FEX
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6M62
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3LQV
 | | Branch Recognition by SF3b14 | | Descriptor: | ADENINE, Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1 | | Authors: | Schellenberg, M.J, MacMillan, A.M. | | Deposit date: | 2010-02-10 | | Release date: | 2011-01-26 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Branch Recognition by SF3b14
Rna, 17, 2011
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3N9U
 | | Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 7, GLYCEROL | | Authors: | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Moche, M, Nielsen, T.N, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | Deposit date: | 2010-05-31 | | Release date: | 2010-07-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im
To be Published
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7C07
 | | Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA. | | Descriptor: | RNA (5'-R(*U*AP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... | | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | | Deposit date: | 2020-04-30 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
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3P5T
 | | CFIm25-CFIm68 complex | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | | Authors: | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | | Deposit date: | 2010-10-11 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
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3Q2S
 | | Crystal Structure of CFIm68 RRM/CFIm25 complex | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | | Authors: | Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. | | Deposit date: | 2010-12-20 | | Release date: | 2011-02-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping.
Structure, 19, 2011
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3Q2T
 | | Crystal Structure of CFIm68 RRM/CFIm25/RNA complex | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6, RNA | | Authors: | Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. | | Deposit date: | 2010-12-20 | | Release date: | 2011-02-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.061 Å) | | Cite: | Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping.
Structure, 19, 2011
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3PGW
 | | Crystal structure of human U1 snRNP | | Descriptor: | DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3', Sm B, Sm G, ... | | Authors: | Weber, G, Trowitzsch, S, Kastner, B, Luehrmann, R, Wahl, M.C. | | Deposit date: | 2010-11-02 | | Release date: | 2010-12-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (4.4 Å) | | Cite: | Functional organization of the Sm core in the crystal structure of human U1 snRNP.
Embo J., 29, 2010
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3P6Y
 | | CF Im25-CF Im68-UGUAA complex | | Descriptor: | 5'-R(*UP*GP*UP*AP*A)-3', Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | | Authors: | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | | Deposit date: | 2010-10-11 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
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7C06
 | | Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | | Descriptor: | RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... | | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | | Deposit date: | 2020-04-30 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
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7C08
 | | Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | | Descriptor: | RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ... | | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | | Deposit date: | 2020-04-30 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
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7BTB
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5YVG
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2XB2
 | | Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery | | Descriptor: | EUKARYOTIC INITIATION FACTOR 4A-III, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Buchwald, G, Ebert, J, Basquin, C, Sauliere, J, Jayachandran, U, Bono, F, Le Hir, H, Conti, E. | | Deposit date: | 2010-04-03 | | Release date: | 2010-05-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1OO0
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1N52
 | | Cap Binding Complex | | Descriptor: | 20 kDa nuclear cap binding protein, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, 80 kDa nuclear cap binding protein, ... | | Authors: | Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R. | | Deposit date: | 2002-11-04 | | Release date: | 2003-02-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
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1N54
 | | Cap Binding Complex m7GpppG free | | Descriptor: | 20 kDa nuclear cap binding protein, 80 kDa nuclear cap binding protein, GLYCEROL | | Authors: | Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R. | | Deposit date: | 2002-11-04 | | Release date: | 2003-02-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
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5Z3G
 | | Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | Authors: | Zhu, X, Zhou, D, Ye, K. | | Deposit date: | 2018-01-06 | | Release date: | 2018-04-11 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate.
Protein Cell, 10, 2019
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6ASO
 | | Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA | | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | | Deposit date: | 2017-08-25 | | Release date: | 2018-05-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
Nat Commun, 9, 2018
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5ZWN
 | | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region) | | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ... | | Authors: | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | | Deposit date: | 2018-05-16 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
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