8XS4
 
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8XVX
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8XW1
 | | Cryo-EM structure of OSCA1.2-V335W-DDM state | | Descriptor: | Calcium permeable stress-gated cation channel 1 | | Authors: | Zhang, Y, Han, Y. | | Deposit date: | 2024-01-15 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.49 Å) | | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
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8XW4
 | | Cryo-EM structure of TMEM63B-Digitonin state | | Descriptor: | CSC1-like protein 2 | | Authors: | Zhang, Y, Han, Y. | | Deposit date: | 2024-01-15 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
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8XS0
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8XVY
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8XRY
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8XW0
 | | Cryo-EM structure of OSCA3.1-GDN state | | Descriptor: | CSC1-like protein ERD4, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | | Authors: | Zhang, Y, Han, Y. | | Deposit date: | 2024-01-15 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
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8YRV
 | | Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid | | Descriptor: | 3-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]oxypropanoic acid, Aminotransferase class IV, MAGNESIUM ION | | Authors: | Matyuta, I.O, Bakunova, A.K, Nikolaeva, A.Y, Popov, V.O, Boyko, K.M. | | Deposit date: | 2024-03-21 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid
To Be Published
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8XS5
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8XW2
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7T6Y
 | | d((CGA)5TGA) parallel-stranded homo-duplex | | Descriptor: | BARIUM ION, DNA (5'-D(*CP*GP*AP*CP*GP*AP*CP*GP*AP*CP*GP*AP*CP*GP*AP*TP*GP*A)-3') | | Authors: | Luteran, E.M, Paukstelis, P.J. | | Deposit date: | 2021-12-14 | | Release date: | 2021-12-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The parallel-stranded d(CGA) duplex is a highly predictable structural motif with two conformationally distinct strands.
Acta Crystallogr D Struct Biol, 78, 2022
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8XAJ
 | | Cryo-EM structure of OSCA1.2-liposome-inside-in open state | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Calcium permeable stress-gated cation channel 1 | | Authors: | Zhang, Y, Han, Y. | | Deposit date: | 2023-12-04 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
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8XW3
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8YC0
 | | T cell receptor V delta2 V gamma9 in GDN | | Descriptor: | CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | | Authors: | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | Deposit date: | 2024-02-17 | | Release date: | 2024-05-08 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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7T10
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7T11
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7ST9
 | | Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | | Authors: | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | | Deposit date: | 2021-11-12 | | Release date: | 2022-03-23 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
Nat.Struct.Mol.Biol., 29, 2022
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7SSX
 | | Structure of human Kv1.3 | | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | | Authors: | Meyerson, J.R, Selvakumar, P. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSZ
 | | Structure of human Kv1.3 with A0194009G09 nanobodies | | Descriptor: | Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | | Authors: | Meyerson, J.R, Selvakumar, P. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSY
 | | Structure of human Kv1.3 (alternate conformation) | | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | | Authors: | Meyerson, J.R, Selvakumar, P. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSV
 | | Structure of human Kv1.3 with Fab-ShK fusion | | Descriptor: | Fab-ShK fusion, heavy chain, light chain, ... | | Authors: | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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8K8E
 | | Human gamma-secretase in complex with a substrate mimetic | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Shi, Y.G, Zhou, R, Wolfe, M.S. | | Deposit date: | 2023-07-29 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Familial Alzheimer mutations stabilize synaptotoxic gamma-secretase-substrate complexes.
Cell Rep, 43, 2024
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2XH6
 | | Clostridium perfringens enterotoxin | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, HEAT-LABILE ENTEROTOXIN B CHAIN, octyl beta-D-glucopyranoside | | Authors: | Briggs, D.C, Naylor, C.E, Smedley III, J.G, MCClane, B.A, Basak, A.K. | | Deposit date: | 2010-06-09 | | Release date: | 2011-04-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structure of the Food-Poisoning Clostridium Perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
J.Mol.Biol., 413, 2011
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7M2T
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