7G9C
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![BU of 7g9c by Molmil](/molmil-images/mine/7g9c) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102141-001 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, N-[2-(methanesulfonyl)phenyl]acetamide, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Method: | X-RAY DIFFRACTION (2.686 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G8O
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![BU of 7g8o by Molmil](/molmil-images/mine/7g8o) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1267800292 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, N-methyl-1H-indole-7-carboxamide, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.579 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G8Q
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![BU of 7g8q by Molmil](/molmil-images/mine/7g8q) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1269220427 | Descriptor: | 8-(methanesulfonyl)quinoline, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G8W
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![BU of 7g8w by Molmil](/molmil-images/mine/7g8w) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1416193393 | Descriptor: | 4-(5-methyl-1H-pyrazol-4-yl)piperidine, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.939 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G8V
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![BU of 7g8v by Molmil](/molmil-images/mine/7g8v) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z133716556 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, N-[(4R)-3,4-dihydro-2H-1-benzopyran-4-yl]methanesulfonamide, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G8Z
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![BU of 7g8z by Molmil](/molmil-images/mine/7g8z) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1493056027 | Descriptor: | 1-[(2R)-1-(methanesulfonyl)pyrrolidin-2-yl]methanamine, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.509 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G9D
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![BU of 7g9d by Molmil](/molmil-images/mine/7g9d) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102179-001 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, N-[3-(2-oxopyrrolidin-1-yl)phenyl]acetamide, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Method: | X-RAY DIFFRACTION (2.659 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G9G
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![BU of 7g9g by Molmil](/molmil-images/mine/7g9g) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102236-001 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, N-(2-methoxyphenyl)acetamide, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Method: | X-RAY DIFFRACTION (2.079 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G9H
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![BU of 7g9h by Molmil](/molmil-images/mine/7g9h) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102245-001 | Descriptor: | (2S)-4-(chloroacetyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Method: | X-RAY DIFFRACTION (2.746 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G82
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![BU of 7g82 by Molmil](/molmil-images/mine/7g82) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1079512010 | Descriptor: | 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.409 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G83
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![BU of 7g83 by Molmil](/molmil-images/mine/7g83) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z108545814 | Descriptor: | 3-propanamido-1-benzofuran-2-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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7G8Y
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![BU of 7g8y by Molmil](/molmil-images/mine/7g8y) | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1449748885 | Descriptor: | DIMETHYL SULFOXIDE, FORMIC ACID, N-(4-methoxyphenyl)glycinamide, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | ARHGEF2 PanDDA analysis group deposition To Be Published
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3I5Z
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![BU of 3i5z by Molmil](/molmil-images/mine/3i5z) | |
3K3Q
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![BU of 3k3q by Molmil](/molmil-images/mine/3k3q) | Crystal Structure of a Llama Antibody complexed with the C. Botulinum Neurotoxin Serotype A Catalytic Domain | Descriptor: | Botulinum neurotoxin type A, ZINC ION, llama Aa1 VHH domain | Authors: | Thompson, A.A, Dong, J, Marks, J.D, Stevens, R.C. | Deposit date: | 2009-10-04 | Release date: | 2010-02-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic alpha-Exosite Binding Region. J.Mol.Biol., 397, 2010
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3HN8
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![BU of 3hn8 by Molmil](/molmil-images/mine/3hn8) | Crystal structure of synaptotagmin | Descriptor: | CALCIUM ION, Synaptotagmin-3, ZINC ION | Authors: | Strop, P, Vrljic, M, Ernst, J, Brunger, A.T. | Deposit date: | 2009-05-30 | Release date: | 2010-02-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat.Struct.Mol.Biol., 17, 2010
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1DFC
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![BU of 1dfc by Molmil](/molmil-images/mine/1dfc) | CRYSTAL STRUCTURE OF HUMAN FASCIN, AN ACTIN-CROSSLINKING PROTEIN | Descriptor: | FASCIN | Authors: | Fedorov, A.A, Fedorov, E.V, Ono, S, Matsumura, F, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 1999-11-18 | Release date: | 2000-11-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein. J.Mol.Biol., 400, 2010
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4R5D
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![BU of 4r5d by Molmil](/molmil-images/mine/4r5d) | |
4R6G
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![BU of 4r6g by Molmil](/molmil-images/mine/4r6g) | |
1DOA
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![BU of 1doa by Molmil](/molmil-images/mine/1doa) | Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi | Descriptor: | GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Hoffman, G.R, Nassar, N, Cerione, R.C. | Deposit date: | 1999-12-20 | Release date: | 2000-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Cell(Cambridge,Mass.), 100, 2000
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4R0Y
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![BU of 4r0y by Molmil](/molmil-images/mine/4r0y) | |
3HI7
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![BU of 3hi7 by Molmil](/molmil-images/mine/3hi7) | Crystal structure of human diamine oxidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive amine oxidase, CALCIUM ION, ... | Authors: | McGrath, A.P, Guss, J.M. | Deposit date: | 2009-05-19 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Structure and inhibition of human diamine oxidase Biochemistry, 48, 2009
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4R58
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![BU of 4r58 by Molmil](/molmil-images/mine/4r58) | |
4R5C
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![BU of 4r5c by Molmil](/molmil-images/mine/4r5c) | |
7XQV
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![BU of 7xqv by Molmil](/molmil-images/mine/7xqv) | The complex of nanobody Rh57 binding to GTP-bound RhoA active form | Descriptor: | ALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Zhang, Y.R, Liu, R, Ding, Y. | Deposit date: | 2022-05-09 | Release date: | 2022-07-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structural insights into the binding of nanobody Rh57 to active RhoA-GTP. Biochem.Biophys.Res.Commun., 616, 2022
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3KZ1
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![BU of 3kz1 by Molmil](/molmil-images/mine/3kz1) | Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ... | Authors: | Chen, Z, Sternweis, P.C, Sprang, S.R. | Deposit date: | 2009-12-07 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation. J.Biol.Chem., 285, 2010
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