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8G6G
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BU of 8g6g by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 5
Descriptor: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Hicks, C.W, Wolberger, C.
Deposit date:2023-02-15
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
8G6Q
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BU of 8g6q by Molmil
H2AK119ub-modified nucleosome ubiquitin position 1
Descriptor: 601 DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Hicks, C.W, Wolberger, C.
Deposit date:2023-02-15
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
8HE5
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BU of 8he5 by Molmil
RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome
Descriptor: DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ...
Authors:Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H.
Deposit date:2022-11-07
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (6.95 Å)
Cite:Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
8H1T
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BU of 8h1t by Molmil
Cryo-EM structure of BAP1-ASXL1 bound to chromatosome
Descriptor: DNA (187-MER), Histone H1.4, Histone H2A type 1-D, ...
Authors:Ge, W, Yu, C, Xu, R.M.
Deposit date:2022-10-04
Release date:2023-02-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
Nature, 616, 2023
8HAM
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BU of 8ham by Molmil
Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2
Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAK
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BU of 8hak by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 4 (4.5 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAI
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BU of 8hai by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAJ
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BU of 8haj by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (4.8 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAG
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BU of 8hag by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAL
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BU of 8hal by Molmil
Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1
Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAN
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BU of 8han by Molmil
Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3
Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAH
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BU of 8hah by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HR1
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BU of 8hr1 by Molmil
Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L.
Deposit date:2022-12-14
Release date:2023-09-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
8HXX
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BU of 8hxx by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S
Descriptor: Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HXY
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BU of 8hxy by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HY0
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BU of 8hy0 by Molmil
Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HQY
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BU of 8hqy by Molmil
Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom
Descriptor: DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ...
Authors:Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L.
Deposit date:2022-12-14
Release date:2023-09-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
8HXZ
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BU of 8hxz by Molmil
Cryo-EM structure of Eaf3 CHD in complex with nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
6INQ
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BU of 6inq by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position)
Descriptor: DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-10-26
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6IQ4
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BU of 6iq4 by Molmil
Nucleosome core particle cross-linked with a hetero-binuclear molecule possessing RAPTA and gold(I) 4-(diphenylphosphino)benzoic acid groups.
Descriptor: 4-diphenylphosphanylbenzoic acid, DNA (145-MER), GOLD ION, ...
Authors:DeFalco, L, Batchelor, L.K, Adhireksan, Z, Dyson, P.J, Davey, C.A.
Deposit date:2018-11-06
Release date:2019-10-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crosslinking Allosteric Sites on the Nucleosome.
Angew.Chem.Int.Ed.Engl., 58, 2019
6IPU
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BU of 6ipu by Molmil
Human nucleosome core particle containing 145 bp of DNA
Descriptor: CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ...
Authors:DeFalco, L, Davey, C.A.
Deposit date:2018-11-04
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
6IRO
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BU of 6iro by Molmil
the crosslinked complex of ISWI-nucleosome in the ADP-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ...
Authors:Yan, L.J, Wu, H, Li, X.M, Gao, N, Chen, Z.C.
Deposit date:2018-11-13
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling.
Nat. Struct. Mol. Biol., 26, 2019
6J50
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BU of 6j50 by Molmil
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation)
Descriptor: DNA (198-MER), DNA (41-MER), DNA-directed RNA polymerase subunit, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6IY3
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BU of 6iy3 by Molmil
Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), Histone H2A, ...
Authors:Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
Deposit date:2018-12-12
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6J4W
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BU of 6j4w by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019

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