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1MHK
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Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn
Descriptor: BROMIDE ION, RNA 12-mer BCh12, RNA 14-mer BCh12
Authors:Szep, S, Wang, J, Moore, P.B.
Deposit date:2002-08-20
Release date:2002-09-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of a 26-nucleotide RNA containing a hook-turn
RNA, 9, 2003
2XZR
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Escherichia coli Immunoglobulin-binding protein EibD 391-438 FUSED TO GCN4 ADAPTORS
Descriptor: CHLORIDE ION, IMMUNOGLOBULIN-BINDING PROTEIN EIBD
Authors:Hartmann, M.D, Hernandez Alvarez, B, Ridderbusch, O, Deiss, S, Lupas, A.N.
Deposit date:2010-11-28
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of E. Coli Igg-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins.
Structure, 19, 2011
4FJG
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RB69 DNA polymerase ternary complex with dATP/dC
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Wang, J, Konigsberg, W.H.
Deposit date:2012-06-11
Release date:2012-12-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase.
J.Am.Chem.Soc., 135, 2013
5VH6
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2.6 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-406) of Elongation Factor G from Bacillus subtilis.
Descriptor: CHLORIDE ION, Elongation factor G
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-04-12
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:2.6 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-406) of Elongation Factor G from Bacillus subtilis.
To Be Published
4FK0
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RB69 DNA polymerase ternary complex with dCTP/dG
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Wang, J, Konigsberg, W.H.
Deposit date:2012-06-12
Release date:2012-12-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase.
J.Am.Chem.Soc., 135, 2013
1MHY
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BU of 1mhy by Molmil
METHANE MONOOXYGENASE HYDROXYLASE
Descriptor: FE (III) ION, METHANE MONOOXYGENASE HYDROXYLASE
Authors:Elango, N, Radhakrishnan, R, Froland, W.A, Waller, B.J, Earhart, C.A, Lipscomb, J.D, Ohlendorf, D.H.
Deposit date:1996-10-21
Release date:1997-05-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b
Protein Sci., 6, 1997
7LNW
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BU of 7lnw by Molmil
I146A mutant of the isopentenyl phosphate kinase from Candidatus methanomethylophilus alvus
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isopentenyl phosphate kinase, [(~{Z})-5-[(azanylidene-$l^{4}-azanylidene)amino]-3-methyl-pent-2-enyl] dihydrogen phosphate
Authors:Thomas, L.M, Singh, S, Johnson, B.P.
Deposit date:2021-02-08
Release date:2021-12-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus .
Acs Chem.Biol., 17, 2022
1MEY
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CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA
Descriptor: CHLORIDE ION, CONSENSUS ZINC FINGER, DNA (5'-D(*AP*TP*GP*AP*GP*GP*CP*AP*GP*AP*AP*CP*T)-3'), ...
Authors:Kim, C.A, Berg, J.M.
Deposit date:1996-09-27
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A 2.2 A Resolution Crystal Structure of a Designed Zinc Finger Protein Bound to DNA
Nat.Struct.Biol., 3, 1996
3UMS
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BU of 3ums by Molmil
Crystal structure of the G202A mutant of human G-alpha-i1
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Lambert, N.A, Johnston, C.A, Cappell, S.D, Kuravi, S, Kimple, A.J, Willard, F.S, Siderovski, D.P.
Deposit date:2011-11-14
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.343 Å)
Cite:Correction for Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity
Proc.Natl.Acad.Sci.USA, 2012
5VOJ
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BU of 5voj by Molmil
Crystal structure of HCV NS3/4A protease in complex with JZ01-15, an analogue of 5172-mcP1P3
Descriptor: NS4A cofactor -- NS3 protein chimera, SULFATE ION, ZINC ION, ...
Authors:Matthew, A.N, Schiffer, C.A.
Deposit date:2017-05-03
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.
J. Med. Chem., 60, 2017
5VHO
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BU of 5vho by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Descriptor: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
Authors:Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
1MFK
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BU of 1mfk by Molmil
Structure of Prokaryotic SECIS mRNA Hairpin
Descriptor: 5'-R(P*GP*GP*CP*GP*GP*UP*UP*GP*CP*AP*GP*GP*UP*CP*UP*GP*CP*AP*CP*CP*GP*CP*C)-3'
Authors:Fourmy, D, Guittet, E, Yoshizawa, S.
Deposit date:2002-08-12
Release date:2002-11-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of Prokaryotic SECIS mRNA Hairpin and its Interaction with Elongation Factor SELB
J.Mol.Biol., 324, 2002
5VOO
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BU of 5voo by Molmil
Methionine synthase folate-binding domain with methyltetrahydrofolate from Thermus thermophilus HB8
Descriptor: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate homocysteine S-methyltransferase, CHLORIDE ION, ...
Authors:Koutmos, M, Yamada, K.
Deposit date:2017-05-03
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The folate-binding module of Thermus thermophilus cobalamin-dependent methionine synthase displays a distinct variation of the classical TIM barrel: a TIM barrel with a `twist'.
Acta Crystallogr D Struct Biol, 74, 2018
2XGE
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BU of 2xge by Molmil
Crystal structure of a designed heterodimeric variant T-A(A)B of the tetracycline repressor
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
J.Mol.Biol., 403, 2010
2XHN
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BU of 2xhn by Molmil
Rhamnogalacturonan lyase from Aspergillus aculeatus K150A active site mutant
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, RHAMNOGALACTURONASE B, ...
Authors:Jensen, M.H, Otten, H, Christensen, U, Borchert, T.V, Christensen, L.L.H, Larsen, S, Lo Leggio, L.
Deposit date:2010-06-18
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural and Biochemical Studies Elucidate the Mechanism of Rhamnogalacturonan Lyase from Aspergillus Aculeatus.
J.Mol.Biol., 404, 2010
1MK6
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BU of 1mk6 by Molmil
SOLUTION STRUCTURE OF THE 8,9-DIHYDRO-8-(N7-GUANYL)-9-HYDROXY-AFLATOXIN B1 ADDUCT MISPAIRED WITH DEOXYADENOSINE
Descriptor: 5'-D(*AP*CP*AP*TP*CP*GP*AP*TP*CP*T)-3', 5'-D(*AP*GP*AP*TP*AP*GP*AP*TP*GP*T)-3', 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1
Authors:Giri, I, Johnston, D.S, Stone, M.P.
Deposit date:2002-08-28
Release date:2002-10-16
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:MISPAIRING OF THE 8,9-DIHYDRO-8-(N7-GUANYL)-9-HYDROXY-AFLATOXIN B1 ADDUCT WITH DEOXYADENOSINE RESULTS IN EXTRUSION OF THE MISMATCHED DA TOWARD THE MAJOR GROOVE
Biochemistry, 41, 2002
7LUI
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BU of 7lui by Molmil
Crystal structure of Vibrio cholerae DsbA in complex with bile salt taurocholate
Descriptor: GLYCEROL, TAUROCHOLIC ACID, Thiol:disulfide interchange protein DsbA
Authors:Wang, G, Heras, B.
Deposit date:2021-02-22
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.
Chemmedchem, 17, 2022
3UMR
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BU of 3umr by Molmil
Crystal structure of the G202D mutant of human G-alpha-i1
Descriptor: CHLORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Johnston, C.A, Afshar, K, Snyder, J.T, Tall, G.G, Gonczy, P, Siderovski, D.P, Willard, F.S.
Deposit date:2011-11-14
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Determinants Underlying the Temperature-sensitive Nature of a G-alpha Mutant in Asymmetric Cell Division of Caenorhabditis elegans
To be Published
1M53
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CRYSTAL STRUCTURE OF ISOMALTULOSE SYNTHASE (PALI) FROM KLEBSIELLA SP. LX3
Descriptor: Isomaltulose Synthase
Authors:Li, N, Swaminathan, K.
Deposit date:2002-07-08
Release date:2003-07-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Isomaltulose synthase (PalI) of Klebsiella sp. LX3. Crystal structure and implication of mechanism
J.Biol.Chem., 278, 2003
1MMN
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BU of 1mmn by Molmil
X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN
Descriptor: MAGNESIUM ION, MYOSIN, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Gulick, A.M, Bauer, C.B, Thoden, J.B, Rayment, I.
Deposit date:1997-07-18
Release date:1997-12-03
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
Biochemistry, 36, 1997
5VKX
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Coordination Chemistry within a Protein Host: Regulation of the Secondary Coordination Sphere
Descriptor: COPPER (II) ION, GLYCEROL, Streptavidin, ...
Authors:Mann, S.I, Heinisch, T.
Deposit date:2017-04-24
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Coordination chemistry within a protein host: regulation of the secondary coordination sphere.
Chem. Commun. (Camb.), 54, 2018
7LSM
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Crystal structure of E.coli DsbA in complex with bile salt taurocholate
Descriptor: DI(HYDROXYETHYL)ETHER, TAUROCHOLIC ACID, Thiol:disulfide interchange protein DsbA
Authors:Wang, G, Heras, B.
Deposit date:2021-02-18
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.786 Å)
Cite:Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.
Chemmedchem, 17, 2022
5VLB
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BU of 5vlb by Molmil
Crystal Structure of Medicago truncatula L-Histidinol Dehydrogenase in Complex with Imidazole
Descriptor: DI(HYDROXYETHYL)ETHER, Histidinol dehydrogenase, chloroplastic, ...
Authors:Ruszkowski, M, Dauter, Z.
Deposit date:2017-04-25
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structures of Medicago truncatula L-Histidinol Dehydrogenase Show Rearrangements Required for NAD(+) Binding and the Cofactor Positioned to Accept a Hydride.
Sci Rep, 7, 2017
5VM5
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BU of 5vm5 by Molmil
Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser bound
Descriptor: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, SODIUM ION, Tryptophan synthase beta chain 1, ...
Authors:Buller, A.R, van Roye, P.
Deposit date:2017-04-26
Release date:2017-05-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble.
J. Am. Chem. Soc., 140, 2018
7LA9
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Crystal structure of the first bromodomain (BD1) of human BRD4 (BRD4-1) in complex with bivalent inhibitor NC-III-49-1
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, CHLORIDE ION, ...
Authors:Karim, M.R, Schonbrunn, E.
Deposit date:2021-01-06
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity.
J.Med.Chem., 65, 2022

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