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2A6I
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Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide KLASIPTHTSPL
Descriptor: Dodecapeptide: KLASIPTHTSPL, Germline antibody 36-65 Fab heavy chain, Germline antibody 36-65 Fab light chain
Authors:Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M.
Deposit date:2005-07-02
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
1CBV
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BU of 1cbv by Molmil
AN AUTOANTIBODY TO SINGLE-STRANDED DNA: COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF THE UNLIGANDED FAB AND A DEOXYNUCLEOTIDE-FAB COMPLEX
Descriptor: DNA (5'-D(*TP*TP*T)-3'), PROTEIN (FAB (BV04-01) AUTOANTIBODY-HEAVY CHAIN), PROTEIN (FAB (BV04-01) AUTOANTIBODY-LIGHT CHAIN)
Authors:Herron, J.N, He, X.M, Ballard, D.W, Blier, P.R, Pace, P.E, Bothwell, A.L.M, Voss Junior, E.W, Edmundson, A.B.
Deposit date:1993-03-16
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex.
Proteins, 11, 1991
8EE5
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BU of 8ee5 by Molmil
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, rhMZ119-D antibody heavy chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-06
Release date:2023-08-30
Method:X-RAY DIFFRACTION (3.583 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EF3
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Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D
Descriptor: rhMZ119-D antibody heavy chain, rhMZ119-D antibody light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.672 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EE8
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Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C in complex with ZIKV E glycoprotein
Descriptor: Envelope protein E, rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-06
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EED
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Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B in complex with ZIKV E glycoprotein
Descriptor: Envelope protein E, rhMZ107-B antibody heavy chain, rhMZ107-B antibody light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (3.487 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EF0
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Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-D
Descriptor: PHOSPHATE ION, ZINC ION, rhMZ104-D antibody heavy chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EF1
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Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ103-A
Descriptor: rhMZ103-A antibody heavy chain, rhMZ103-A antibody light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EEE
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BU of 8eee by Molmil
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-d in complex with ZIKV E glycoprotein
Descriptor: Envelope protein E, SULFATE ION, rhMZ104-D antibody heavy chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.819 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EEZ
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BU of 8eez by Molmil
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C
Descriptor: rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EF2
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BU of 8ef2 by Molmil
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B
Descriptor: PHOSPHATE ION, rhMZ107-B antibody heavy chain, rhMZ107-B antibody light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2022-09-07
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
2A6K
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BU of 2a6k by Molmil
Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR
Descriptor: DODECAPEPTIDE: SLGDNLTNHNLR, Germline antibody 36-65 Fab heavy chain, Germline antibody 36-65 Fab light chain
Authors:Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M.
Deposit date:2005-07-03
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
3LEY
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BU of 3ley by Molmil
2F5 Epitope scaffold elicited anti-HIV-1 monoclonal antibody 6a7 in complex with HIV-1 GP41
Descriptor: 6a7 Antibody Heavy Chain, 6a7 Antibody Light Chain, Envelope glycoprotein gp41, ...
Authors:Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
Deposit date:2010-01-15
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
2V7H
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BU of 2v7h by Molmil
Crystal structure of an immunogen specific anti-mannopyranoside monoclonal antibody Fab fragment
Descriptor: MONOCLONAL ANTIBODY
Authors:Krishnan, L, Sahni, G, Kaur, K.J, Salunke, D.M.
Deposit date:2007-07-30
Release date:2008-08-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Role of Antibody Paratope Conformational Flexibility in the Manifestation of Molecular Mimicry.
Biophys.J., 94, 2008
7YC5
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BU of 7yc5 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from K202.B, bispecific antibody, ...
Authors:Yoo, Y, Cho, H.S.
Deposit date:2022-06-30
Release date:2023-07-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants.
Antiviral Res., 212, 2023
7N4J
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BU of 7n4j by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2173.
Descriptor: Spike protein S1, WRAIR-2173 antibody Fab heavy chain, WRAIR-2173 antibody Fab light chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.207 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4I
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BU of 7n4i by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057.
Descriptor: GLYCEROL, Spike protein S1, WRAIR-2057 Antibody Fab Heavy Chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.284 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4M
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BU of 7n4m by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2151.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, WRAIR-2151 antibody Fab heavy chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4L
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BU of 7n4l by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2125.
Descriptor: Spike protein S1, WRAIR-2125 antibody Fab heavy chain, WRAIR-2125 antibody Fab light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.601 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
2A6D
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BU of 2a6d by Molmil
Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide RLLIADPPSPRE
Descriptor: Dodecapeptide, RLLIADPPSPRE, Germline antibody 36-65 Fab Heavy chain, ...
Authors:Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M.
Deposit date:2005-07-02
Release date:2006-06-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
2Z4Q
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BU of 2z4q by Molmil
Crystal structure of a murine antibody FAB 528
Descriptor: CADMIUM ION, CHLORIDE ION, anti egfr antibody fab, ...
Authors:Nakanishi, T, Tsumoto, K, Asano, R, Kondo, H, Kumagai, I.
Deposit date:2007-06-22
Release date:2007-10-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528
J.Biol.Chem., 283, 2008
3MNV
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BU of 3mnv by Molmil
Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment
Descriptor: 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ...
Authors:Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F.
Deposit date:2010-04-22
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.
Nat.Struct.Mol.Biol., 17, 2010
3AB0
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BU of 3ab0 by Molmil
Crystal structure of complex of the Bacillus anthracis major spore surface protein BclA with ScFv antibody fragment
Descriptor: BclA protein, antibody ScFv fragment, heavy chain, ...
Authors:Streltsov, V.A.
Deposit date:2009-11-28
Release date:2010-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Isolation, kinetic analysis, and structural characterization of an antibody targeting the Bacillus anthracis major spore surface protein BclA.
Proteins, 79, 2011
3LEV
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BU of 3lev by Molmil
HIV-1 antibody 2F5 in complex with epitope scaffold ES2
Descriptor: 2F5 ANTIBODY HEAVY CHAIN, 2F5 ANTIBODY LIGHT CHAIN, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
Deposit date:2010-01-15
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
7TB8
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BU of 7tb8 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhou, T, Tsybovsky, T, Kwong, P.D.
Deposit date:2021-12-21
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022

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