PDB: 737 resultsInfo pagesStatus searchChemie searchBIRD

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6Y7W	Fragment KCL_1337 in complex with MAP kinase p38-alpha Descriptor: (2~{R})-~{N}-[(2-azanyl-2-adamantyl)methyl]-4-[6-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]pyridin-3-yl]sulfonyl-2-methyl-morpholine-2-carboxamide, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, CALCIUM ION, ... Authors: De Nicola, G.F, Nichols, C.E. Deposit date: 2020-03-02 Release date: 2020-03-11 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
5ER8	Crystal structure of cyclization domain of Phomopsis amygdali fusicoccadiene synthase complexed with manganese ions and neridronate Descriptor: (6-azanyl-1-oxidanyl-1-phosphono-hexyl)phosphonic acid, CHLORIDE ION, Fusicoccadiene synthase, ... Authors: Chen, M, Christianson, D.W. Deposit date: 2015-11-13 Release date: 2016-01-20 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase. Acs Chem.Biol., 11, 2016
8OV5	PERIDININ-CHLOROPHYLL-PROTEIN OF AMPHIDINIUM CARTERAE, 100K Descriptor: CHLOROPHYLL A, PERIDININ, Peridinin-chlorophyll a-binding protein 1, ... Authors: Hofmann, E, Johanning, S. Deposit date: 2023-04-25 Release date: 2024-05-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Structural and spectroscopic characterization of the peridinin-chlorophyll a-protein (PCP) complex from Heterocapsa pygmaea (HPPCP). Biochim Biophys Acta Bioenerg, 1866, 2024
6XXF	1.7 Angstrom crystal structure of Ca/CaM:RyR2 peptide complex Descriptor: CALCIUM ION, Calmodulin-2, RyR2 Peptide Authors: Antonyuk, S, Helassa, N. Deposit date: 2020-01-27 Release date: 2021-02-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: CPVT-associated calmodulin variants N53I and A102V dysregulate Ca2+ signalling via different mechanisms. J.Cell.Sci., 135, 2022
8RQE	Composite map of bacteriophage JBD30 capsid - neck complex Descriptor: Bacteriophage Mu GpT domain-containing protein, DUF1320 domain-containing protein, Mu-like prophage FluMu N-terminal domain-containing protein, ... Authors: Valentova, L, Fuzik, T, Plevka, P. Deposit date: 2024-01-18 Release date: 2024-08-14 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (8 Å) Cite: Structure and replication of Pseudomonas aeruginosa phage JBD30. Embo J., 43, 2024
4V99	The Crystallographic Structure of Panicum Mosaic Virus Descriptor: 5'-R(P*UP*UP*AP*AP*UP*AP*UP*UP*UP*UP*UP*AP*UP*UP*UP*UP*U)-3', CALCIUM ION, Capsid protein Authors: Makino, D.L, Larson, S.B, McPherson, A. Deposit date: 2012-07-04 Release date: 2014-07-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The crystallographic structure of Panicum Mosaic Virus (PMV). J.Struct.Biol., 181, 2013
4U53	Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome Descriptor: (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, 18S ribosomal RNA, 25S ribosomal RNA, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
9MJN	Near complete virion structure of bacteriophage PhiTE Descriptor: Cyanophage baseplate Pam3 plug gp18 domain-containing protein, Dit-like phage tail protein N-terminal domain-containing protein, Head stabilization/decoration protein, ... Authors: Hodgkinson-Bean, J, Ayala, R. Deposit date: 2024-12-16 Release date: 2025-04-16 Method: ELECTRON MICROSCOPY (12.7 Å) Cite: Global structural survey of the flagellotropic myophage phi TE infecting agricultural pathogen Pectobacterium atrosepticum. Nat Commun, 16, 2025
4U4N	Crystal structure of Edeine bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U3M	Crystal structure of Anisomycin bound to the yeast 80S ribosome Descriptor: 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-22 Release date: 2014-10-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U52	Crystal structure of Nagilactone C bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4V9A	Crystal Structure of the 70S ribosome with tetracycline. Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... Authors: Jenner, L, Yusupov, M, Yusupova, G. Deposit date: 2012-07-18 Release date: 2014-07-09 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.2999 Å) Cite: Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
7RQD	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MTI-tripeptidyl-tRNA analog ACCA-ITM, and chloramphenicol at 2.50A resolution Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... Authors: Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. Deposit date: 2021-08-06 Release date: 2022-01-26 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
7EZX	Structure of the phycobilisome from the red alga Porphyridium purpureum in Middle Light Descriptor: Allophycocyanin alpha subunit, Allophycocyanin beta 18 subunit, Allophycocyanin beta subunit, ... Authors: Ma, J.F, Sui, S.-F. Deposit date: 2021-06-02 Release date: 2022-09-28 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (3 Å) Cite: The structural basis for light acclimation in phycobilisome light harvesting systems systems in Porphyridium purpureum Commun Biol, 6, 2023
6Q3G	Structure of native bacteriophage P68 Descriptor: Arstotzka protein, Head fiber protein, Inner core protein, ... Authors: Dominik, H, Karel, S, Fuzik, T, Plevka, P. Deposit date: 2018-12-04 Release date: 2019-11-06 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure and genome ejection mechanism ofStaphylococcus aureusphage P68. Sci Adv, 5, 2019
4V8I	Crystal structure of YfiA bound to the 70S ribosome. Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Polikanov, Y.S, Blaha, G.M, Steitz, T.A. Deposit date: 2011-12-12 Release date: 2014-07-09 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science, 336, 2012
4V9R	Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. Deposit date: 2013-12-05 Release date: 2014-07-09 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (3 Å) Cite: The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
4V8H	Crystal structure of HPF bound to the 70S ribosome. Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Polikanov, Y.S, Blaha, G.M, Steitz, T.A. Deposit date: 2011-12-11 Release date: 2014-07-09 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis. Science, 336, 2012
4V9S	Crystal structure of antibiotic GE82832 bound to 70S ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. Deposit date: 2013-12-05 Release date: 2014-07-09 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
4V95	Crystal structure of YAEJ bound to the 70S ribosome Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A. Deposit date: 2012-01-27 Release date: 2014-07-09 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science, 335, 2012
4V97	Crystal structure of the bacterial ribosome ram mutation G299A. Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M. Deposit date: 2012-04-06 Release date: 2014-07-09 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.516 Å) Cite: Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc.Natl.Acad.Sci.USA, 110, 2013
4W4G	Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M. Deposit date: 2014-08-14 Release date: 2015-10-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
4V8J	Crystal structure of the bacterial ribosome ram mutation G347U. Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M. Deposit date: 2011-12-20 Release date: 2014-07-09 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc.Natl.Acad.Sci.USA, 110, 2013
4W2F	Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V. Deposit date: 2014-09-12 Release date: 2014-10-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol.Cell, 56, 2014
4V7M	The structures of Capreomycin bound to the 70S ribosome. Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Stanley, R.E, Blaha, G. Deposit date: 2009-11-12 Release date: 2014-07-09 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (3.45 Å) Cite: The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat.Struct.Mol.Biol., 17, 2010

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