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6DN7	SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor Descriptor: CHLORIDE ION, SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor Authors: Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. Deposit date: 2018-06-06 Release date: 2019-04-17 Last modified: 2020-01-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
2IHS	Crystal structure of the B30.2/SPRY domain of GUSTAVUS in complex with a 20-residue VASA peptide Descriptor: 20-mer from ATP-dependent RNA helicase vasa, CG2944-PF, isoform F Authors: Woo, J.S, Park, S.Y, Oh, B.H. Deposit date: 2006-09-27 Release date: 2007-01-16 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Basis for Protein Recognition by B30.2/SPRY Domains Mol.Cell, 24, 2006
2JK9	The structure of splA-ryanodine receptor domain and SOCS box containing 1 in complex with a PAR-4 peptide Descriptor: PRKC APOPTOSIS WT1 REGULATOR PROTEIN, SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 Authors: Filippakopoulos, P, Bullock, A, Keates, T, Savitsky, P, Murray, J.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wickstroem, M, Bountra, C, Knapp, S. Deposit date: 2008-08-22 Release date: 2008-09-16 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4. J.Mol.Biol., 401, 2010
5JI7	The Crystal Structure Of IUS-SPRY Domain From RanBPM/9 Descriptor: Ran-binding protein 9 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5JI9	The Crystal Structure Of IUS-SPRY Domain From RanBPM/9 Descriptor: Ran-binding protein 9 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5JIU	The crystal structure of RanBPM/9 IUS-SPRY domain in complex with DDX-4 peptide Descriptor: CHLORIDE ION, Probable ATP-dependent RNA helicase DDX4, Ran-binding protein 9 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.054 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5JIA	The Crystal Structure Of IUS-SPRY Domain From RanBP10 Descriptor: IMIDAZOLE, Ran-binding protein 10 Authors: Hong, S.K, Kim, K.-H, Kim, E.E. Deposit date: 2016-04-22 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
7QRZ	Crystal structure of B30.2 PRYSPRY domain of MID2 Descriptor: 1,2-ETHANEDIOL, Probable E3 ubiquitin-protein ligase MID2, SULFATE ION Authors: Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-01-12 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Crystal structure of B30.2 PRYSPRY domain of MID2 To Be Published
7QS5	Crystal structure of B30.2 PRYSPRY domain of TRIM67 Descriptor: 1,2-ETHANEDIOL, Tripartite motif-containing protein 67 Authors: Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-01-12 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of B30.2 PRYSPRY domain of TRIM67 To Be Published
7QRY	Crystal structure of B30.2 PRYSPRY domain of MID1 Descriptor: E3 ubiquitin-protein ligase Midline-1 Authors: Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-01-12 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Crystal structure of B30.2 PRYSPRY domain of MID1 To Be Published
6J6L	Crystal structure of mouse Ryanodine Receptor 2 SPRY1 Domain (650-844) disease mutant I784F Descriptor: ISOPROPYL ALCOHOL, Ryanodine receptor 2 Authors: Ma, R, Lin, L, Yuchi, Z. Deposit date: 2019-01-15 Release date: 2020-01-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.452 Å) Cite: A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes. Sci Rep, 11, 2021
6JKJ	Crystal structure of human SPSB2 in the apo-state Descriptor: SPRY domain-containing SOCS box protein 2 Authors: Luo, Y, Kuang, Z. Deposit date: 2019-03-01 Release date: 2019-07-03 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the SPRY domain of human SPSB2 in the apo state. Acta Crystallogr.,Sect.F, 75, 2019
6KEY	Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2) Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 Authors: Li, K, Kuang, Z. Deposit date: 2019-07-05 Release date: 2020-07-01 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase. Nitric Oxide, 113-114, 2021
6LT9	The crystal structure of diamondback moth ryanodine receptor SPRY1 domain Descriptor: GLYCEROL, Ryanodine receptor 1, SODIUM ION Authors: Zhou, Y, Lin, L, Yuchi, Z. Deposit date: 2020-01-22 Release date: 2021-01-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.801 Å) Cite: The crystal structure of diamondback moth ryanodine receptor SPRY1 domain To Be Published
6JWM	Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 Authors: Li, K, Kuang, Z. Deposit date: 2019-04-21 Release date: 2020-04-22 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Crystal structure of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction To Be Published
6JWN	Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2 Authors: Li, K, Kuang, Z. Deposit date: 2019-04-21 Release date: 2020-04-22 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Crystal structure of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction To Be Published
6KIM	Crystal structure of diamondback moth ryanodine receptor SPRY2 domain Descriptor: GLYCEROL, Ryanodine receptor Authors: Zhou, Y, Lin, L, Yuchi, Z. Deposit date: 2019-07-19 Release date: 2020-07-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.057 Å) Cite: Crystal structure of diamondback moth ryanodine receptor SPRY2 domain To Be Published
3KB5	PRY-SPRY domain of human TRIM72 Descriptor: Tripartite motif-containing protein 72 Authors: Park, E.Y, Kwon, O.-B, Jeong, B.-C, Song, H.K. Deposit date: 2009-10-20 Release date: 2009-12-22 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of PRY-SPRY domain of human TRIM72 Proteins, 2009
8HJT	Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP Descriptor: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Butyrophylin 3, ... Authors: Yang, Y.Y, Shen, P.P, Li, X, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. Deposit date: 2022-11-23 Release date: 2023-09-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
4UWE	Structure of the ryanodine receptor at resolution of 8.5 A in partially open state Descriptor: RYANODINE RECEPTOR 1 Authors: Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S. Deposit date: 2014-08-11 Release date: 2014-12-10 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (8.5 Å) Cite: Architecture and Conformational Switch Mechanism of the Ryanodine Receptor. Nature, 517, 2015
8PD6	Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase TRIM58, ... Authors: Renatus, M, Hoegenauer, K, Schroeder, M. Deposit date: 2023-06-11 Release date: 2024-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. Acs Med.Chem.Lett., 14, 2023
8PD4	Crystal structure of TRIM58 PRY-SPRY domain Descriptor: E3 ubiquitin-protein ligase TRIM58 Authors: Renatus, M, Schroeder, M. Deposit date: 2023-06-11 Release date: 2024-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.714 Å) Cite: Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. Acs Med.Chem.Lett., 14, 2023
4V1P	BTN3 Structure Descriptor: BUTYROPHILIN SUBFAMILY 3 MEMBER A1 Authors: James, L.C. Deposit date: 2014-09-30 Release date: 2015-07-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Activation of Human Gammadelta T Cells by Cytosolic Interactions of Btn3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin. J.Immunol., 194, 2015
4WVM	Stonustoxin structure Descriptor: Stonustoxin subunit alpha, Stonustoxin subunit beta Authors: Ellisdon, A.M, Panjikar, S, Whisstock, J.C, McGowan, S. Deposit date: 2014-11-06 Release date: 2015-12-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Stonefish toxin defines an ancient branch of the perforin-like superfamily. Proc.Natl.Acad.Sci.USA, 112, 2015
7OVX	E3 RING ligase binding domain Descriptor: E3 ubiquitin-protein ligase TRIM7, Peptide G Authors: James, L.C. Deposit date: 2021-06-15 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: E3 ligase targeting domain To Be Published

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