1W3B
| The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | Descriptor: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | Authors: | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | Deposit date: | 2004-07-14 | Release date: | 2004-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha Nat.Struct.Mol.Biol., 11, 2004
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6EOU
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3LCA
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2NC9
| Apo solution structure of Hop TPR2A | Descriptor: | Stress-induced-phosphoprotein 1 | Authors: | Darby, J.F, Vidler, L.R, Simpson, P.J, Matthews, S.J, Sharp, S.Y, Pearl, L.H, Hoelder, S, Workman, P. | Deposit date: | 2016-03-23 | Release date: | 2017-03-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches. Sci Rep, 10, 2020
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3NF1
| Crystal structure of the TPR domain of kinesin light chain 1 | Descriptor: | Kinesin light chain 1 | Authors: | Tong, Y, Tempel, W, Shen, L, Shen, Y, Nedyalkova, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-06-09 | Release date: | 2011-05-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the TPR domain of kinesin light chain 1 to be published
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3ZFW
| Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide | Descriptor: | KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 | Authors: | Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P. | Deposit date: | 2012-12-12 | Release date: | 2013-04-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Kinesin-1:Cargo Recognition. Science, 340, 2013
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6FO1
| Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... | Authors: | Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. | Deposit date: | 2018-02-05 | Release date: | 2018-04-04 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nat Commun, 9, 2018
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6FUZ
| Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 | Descriptor: | GLYCEROL, Kinesin light chain 1,Kinesin light chain 1,C-Jun-amino-terminal kinase-interacting protein 1, nanobody | Authors: | Pernigo, S, Dodding, M.P, Steiner, R.A. | Deposit date: | 2018-02-28 | Release date: | 2018-05-02 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, 2018
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7Y4I
| Crystal structure of SPINDLY in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY | Authors: | Xu, S.T, Wan, L.H. | Deposit date: | 2022-06-14 | Release date: | 2022-12-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural insights into mechanism and specificity of the plant protein O-fucosyltransferase SPINDLY. Nat Commun, 13, 2022
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5OJ8
| Crystal structure of the KLC1-TPR domain ([A1-B5] fragment) | Descriptor: | Kinesin light chain 1, PHOSPHATE ION | Authors: | Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J. | Deposit date: | 2017-07-20 | Release date: | 2017-10-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.247 Å) | Cite: | Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain. PLoS ONE, 12, 2017
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5G05
| Cryo-EM structure of combined apo phosphorylated APC | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | Authors: | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | Deposit date: | 2016-03-16 | Release date: | 2016-05-25 | Last modified: | 2019-09-11 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation. Nature, 533, 2016
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5FJY
| Crystal structure of mouse kinesin light chain 2 (residues 161-480) | Descriptor: | KINESIN LIGHT CHAIN 2, UNKNOWN PEPTIDE | Authors: | Pernigo, S, Yip, Y.Y, Sanger, A, Xu, M, Dodding, M.P, Steiner, R.A. | Deposit date: | 2015-10-14 | Release date: | 2016-02-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | The Light Chains of Kinesin-1 are Autoinhibited. Proc.Natl.Acad.Sci.USA, 113, 2016
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6TNT
| SUMOylated apoAPC/C with repositioned APC2 WHB domain | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Barford, D, Yatskevich, S. | Deposit date: | 2019-12-10 | Release date: | 2021-01-13 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation. Cell Rep, 34, 2021
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7YEH
| Cryo-EM structure of human OGT-OGA complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | Authors: | Lu, P, Liu, Y, Yu, H, Gao, H. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14, 2023
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7YEA
| Human O-GlcNAc transferase Dimer | Descriptor: | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | Authors: | Gao, H, Lu, P, Liu, Y. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14, 2023
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8PKP
| Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. | Deposit date: | 2023-06-27 | Release date: | 2023-07-19 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1 To Be Published
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4RG7
| Crystal structure of APC3 | Descriptor: | Cell division cycle protein 27 homolog | Authors: | Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A. | Deposit date: | 2014-09-29 | Release date: | 2014-12-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome. J.Mol.Biol., 427, 2015
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4RG6
| Crystal structure of APC3-APC16 complex | Descriptor: | Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog | Authors: | Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A. | Deposit date: | 2014-09-29 | Release date: | 2014-12-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome. J.Mol.Biol., 427, 2015
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4RG9
| Crystal structure of APC3-APC16 complex (Selenomethionine Derivative) | Descriptor: | Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog | Authors: | Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A. | Deposit date: | 2014-09-29 | Release date: | 2014-12-24 | Last modified: | 2017-08-02 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome. J.Mol.Biol., 427, 2015
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3VTY
| Crystal structure of MamA | Descriptor: | CHLORIDE ION, MamA | Authors: | Zeytuni, N, Baran, D, Davidov, G, Zarivach, R. | Deposit date: | 2012-06-08 | Release date: | 2012-10-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA J.Struct.Biol., 180, 2012
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3UQ3
| TPR2AB-domain:pHSP90-complex of yeast Sti1 | Descriptor: | Heat shock protein, Heat shock protein STI1 | Authors: | Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J. | Deposit date: | 2011-11-19 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Embo J., 31, 2012
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3VTX
| Crystal structure of MamA protein | Descriptor: | GLYCEROL, MamA | Authors: | Zeytuni, N, Baran, D, Davidov, G, Zarivach, R. | Deposit date: | 2012-06-08 | Release date: | 2012-10-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA J.Struct.Biol., 180, 2012
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3FP2
| Crystal structure of Tom71 complexed with Hsp82 C-terminal fragment | Descriptor: | ATP-dependent molecular chaperone HSP82, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Li, J, Qian, X, Hu, J, Sha, B. | Deposit date: | 2009-01-03 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading. J.Biol.Chem., 284, 2009
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8A5Y
| S. cerevisiae apo unphosphorylated APC/C. | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... | Authors: | Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. | Deposit date: | 2022-06-16 | Release date: | 2022-08-31 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states To Be Published
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3FP3
| Crystal structure of Tom71 | Descriptor: | CHLORIDE ION, SULFATE ION, TPR repeat-containing protein YHR117W | Authors: | Li, J, Qian, X, Hu, J, Sha, B. | Deposit date: | 2009-01-03 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading. J.Biol.Chem., 284, 2009
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