2CSW
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6AR0
| Structure of human SLMAP FHA domain | Descriptor: | Sarcolemmal membrane-associated protein | Authors: | Ni, L, Luo, X. | Deposit date: | 2017-08-21 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK. Elife, 6, 2017
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6AR2
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1FHR
| SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE | Descriptor: | DNA REPAIR PROTEIN RAD9, PROTEIN KINASE SPK1 | Authors: | Byeon, I.-J.L, Liao, H, Yongkiettrakul, S, Tsai, M.-D. | Deposit date: | 2000-08-02 | Release date: | 2000-10-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. J.Mol.Biol., 302, 2000
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1FHQ
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6C4U
| Engineered FHA with Myc-pTBD peptide | Descriptor: | Forkhead-associated 1, GLYCEROL, Myc-pTBD peptide | Authors: | Kall, S.L, Lavie, A. | Deposit date: | 2018-01-12 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc. N Biotechnol, 45, 2018
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1G6G
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6CAH
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1G3G
| NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53 | Descriptor: | PROTEIN KINASE SPK1 | Authors: | Yuan, C, Liao, H, Su, M, Yongkiettrakul, S, Byeon, I.-J.L, Tsai, M.-D. | Deposit date: | 2000-10-24 | Release date: | 2001-01-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9 J.Mol.Biol., 304, 2000
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1GXC
| FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide | Descriptor: | SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE | Authors: | Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | Deposit date: | 2002-04-02 | Release date: | 2002-06-13 | Last modified: | 2016-12-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2 Mol.Cell, 9, 2002
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6CCD
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3UN0
| Crystal Structure of MDC1 FHA Domain | Descriptor: | Mediator of DNA damage checkpoint protein 1, SULFATE ION | Authors: | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | Deposit date: | 2011-11-15 | Release date: | 2011-12-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
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3UMZ
| Crystal Structure of the human MDC1 FHA Domain | Descriptor: | Mediator of DNA damage checkpoint protein 1 | Authors: | Luo, S, Ye, K. | Deposit date: | 2011-11-15 | Release date: | 2012-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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3UOT
| Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus | Descriptor: | Mediator of DNA damage checkpoint protein 1 | Authors: | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | Deposit date: | 2011-11-17 | Release date: | 2011-12-28 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
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3UNM
| Crystal Structure of The Human MDC1 FHA Domain | Descriptor: | Mediator of DNA damage checkpoint protein 1 | Authors: | Luo, S, Ye, K. | Deposit date: | 2011-11-16 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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3UNN
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3VA4
| Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide | Descriptor: | Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2 | Authors: | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | Deposit date: | 2011-12-28 | Release date: | 2012-02-01 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry, 2012
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3I0N
| Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | Descriptor: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | Authors: | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | Deposit date: | 2009-06-25 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage Cell(Cambridge,Mass.), 139, 2009
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3HX1
| Crystal structure of the Slr1951 protein from Synechocystis sp. Northeast Structural Genomics Consortium Target SgR167A | Descriptor: | Slr1951 protein | Authors: | Vorobiev, S, Chen, Y, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-19 | Release date: | 2009-06-30 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the Slr1951 protein from Synechocystis sp. To be Published
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3HUF
| Structure of the S. pombe Nbs1-Ctp1 complex | Descriptor: | DNA repair and telomere maintenance protein nbs1, Double-strand break repair protein ctp1, THIOCYANATE ION | Authors: | Williams, R.S, Guenther, G, Tainer, J.A. | Deposit date: | 2009-06-13 | Release date: | 2009-10-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell(Cambridge,Mass.), 139, 2009
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3I0M
| Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | Descriptor: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | Authors: | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | Deposit date: | 2009-06-25 | Release date: | 2009-10-13 | Last modified: | 2012-05-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage Cell(Cambridge,Mass.), 139, 2009
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3HUE
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2JQJ
| NMR structure of yeast Dun1 FHA domain | Descriptor: | DNA damage response protein kinase DUN1 | Authors: | Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M. | Deposit date: | 2007-06-02 | Release date: | 2008-06-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Mol.Cell, 30, 2008
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2JQL
| NMR structure of the yeast Dun1 FHA domain in complex with a doubly phosphorylated (pT) peptide derived from Rad53 SCD1 | Descriptor: | DNA damage response protein kinase DUN1, Serine/threonine-protein kinase RAD53 | Authors: | Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M. | Deposit date: | 2007-06-02 | Release date: | 2008-06-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Mol.Cell, 30, 2008
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5YYZ
| Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. | Descriptor: | Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1 | Authors: | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-12-11 | Release date: | 2018-10-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
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