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1TPK
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BU of 1tpk by Molmil
CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION
Descriptor: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR
Authors:De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A.
Deposit date:1991-09-24
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.
Biochemistry, 31, 1992
1URK
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BU of 1urk by Molmil
SOLUTION STRUCTURE OF THE AMINO TERMINAL FRAGMENT OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR
Descriptor: PLASMINOGEN ACTIVATOR, alpha-L-fucopyranose
Authors:Hansen, A.P, Petros, A.M, Meadows, R.P, Nettesheim, D.G, Mazar, A.P, Olejniczak, E.T, Xu, R.X, Pederson, T.M, Henkin, J, Fesik, S.W.
Deposit date:1994-01-10
Release date:1995-05-08
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator.
Biochemistry, 33, 1994
2DOH
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BU of 2doh by Molmil
The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group A streptococcal surface protein PAM
Descriptor: 1,4-DIETHYLENE DIOXIDE, Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H.
Deposit date:2006-04-29
Release date:2006-12-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2DOI
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BU of 2doi by Molmil
The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM
Descriptor: Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H.
Deposit date:2006-04-29
Release date:2006-12-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2FD6
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BU of 2fd6 by Molmil
Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ...
Authors:Huang, M, Huai, Q, Li, Y.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human urokinase plasminogen activator in complex with its receptor
Science, 311, 2006
2FEB
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BU of 2feb by Molmil
NMR Solution Structure, Dynamics and Binding Properties of the Kringle IV Type 8 module of apolipoprotein(a)
Descriptor: Apolipoprotein(a)
Authors:Chitayat, S, Kanelis, V, Koschinsky, M.L, Smith, S.P.
Deposit date:2005-12-15
Release date:2006-12-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a).
Biochemistry, 46, 2007
2HPP
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BU of 2hpp by Molmil
Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
Descriptor: ALPHA-THROMBIN HEAVY CHAIN, ALPHA-THROMBIN LIGHT CHAIN, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1993-04-28
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Biochemistry, 32, 1993
2HPQ
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BU of 2hpq by Molmil
Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1993-04-28
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Biochemistry, 32, 1993
2I9A
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BU of 2i9a by Molmil
Crystal structure of the free aminoterminal fragment of urokinase type plasminogen activator (ATF)
Descriptor: PHOSPHATE ION, Urokinase-type plasminogen activator
Authors:Lubkowski, J, Barinka, C.
Deposit date:2006-09-05
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol., 363, 2006
2I9B
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BU of 2i9b by Molmil
Crystal structure of ATF-urokinase receptor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Urokinase plasminogen activator surface receptor, ...
Authors:Lubkowski, J, Barinka, C.
Deposit date:2006-09-05
Release date:2007-01-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol., 363, 2006
2KNF
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BU of 2knf by Molmil
Solution structure and functional characterization of human plasminogen kringle 5
Descriptor: Plasminogen
Authors:Battistel, M.D, Grishaev, A, An, S.A, Castellino, F.J, Llinas, M.
Deposit date:2009-08-21
Release date:2009-10-27
Last modified:2021-10-13
Method:SOLUTION NMR
Cite:Solution structure and functional characterization of human plasminogen kringle 5.
Biochemistry, 48, 2009
2L0S
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BU of 2l0s by Molmil
Solution Structure of Human Plasminogen Kringle 3
Descriptor: Plasminogen
Authors:Christen, M.T, Frank, P, Schaller, J, Llinas, M.
Deposit date:2010-07-15
Release date:2010-08-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Human plasminogen kringle 3: solution structure, functional insights, phylogenetic landscape.
Biochemistry, 49, 2010
2PF1
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BU of 2pf1 by Molmil
STRUCTURE OF BOVINE PROTHROMBIN FRAGMENT 1 REFINED AT 2.25 ANGSTROMS RESOLUTION
Descriptor: PROTHROMBIN FRAGMENT 1
Authors:Seshadri, T.P, Tulinsky, A, Skrzypczak-Jankun, E, Park, C.H.
Deposit date:1992-09-17
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of bovine prothrombin fragment 1 refined at 2.25 A resolution.
J.Mol.Biol., 220, 1991
2PF2
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BU of 2pf2 by Molmil
THE CA+2 ION AND MEMBRANE BINDING STRUCTURE OF THE GLA DOMAIN OF CA-PROTHROMBIN FRAGMENT 1
Descriptor: CALCIUM ION, PROTHROMBIN FRAGMENT 1
Authors:Soriano-Garcia, M, Padmanabhan, K, De vos, A.M, Tulinsky, A.
Deposit date:1991-12-08
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1.
Biochemistry, 31, 1992
2PK4
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BU of 2pk4 by Molmil
THE REFINED STRUCTURE OF THE EPSILON-AMINOCAPROIC ACID COMPLEX OF HUMAN PLASMINOGEN KRINGLE
Descriptor: 6-AMINOHEXANOIC ACID, HUMAN PLASMINOGEN KRINGLE 4
Authors:Tulinsky, A, Wu, T.-P.
Deposit date:1991-07-18
Release date:1993-10-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4.
Biochemistry, 30, 1991
2QJ2
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BU of 2qj2 by Molmil
A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
Descriptor: Hepatocyte growth factor, SULFATE ION
Authors:Tolbert, W.D, Daugherty, J, Gao, C.-F, Xe, Q, Miranti, C, Gherardi, E, Vande Woude, G, Xu, H.E.
Deposit date:2007-07-06
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QJ4
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BU of 2qj4 by Molmil
A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
Descriptor: Hepatocyte growth factor, SULFATE ION
Authors:Tolbert, W.D, Daugherty, J, Gao, C.-F, Xe, Q, Miranti, C, Gherardi, E, Vande Woude, G, Xu, H.E.
Deposit date:2007-07-06
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist
Proc.Natl.Acad.Sci.Usa, 104, 2007
2SPT
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BU of 2spt by Molmil
DIFFERENCES IN THE METAL ION STRUCTURE BETWEEN SR-AND CA-PROTHROMBIN FRAGMENT 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTHROMBIN, STRONTIUM ION
Authors:Tulinsky, A.
Deposit date:1994-02-01
Release date:1994-05-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1.
Biochemistry, 33, 1994
3BT1
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BU of 3bt1 by Molmil
Structure of urokinase receptor, urokinase and vitronectin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
Authors:Huang, M.
Deposit date:2007-12-27
Release date:2008-03-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3BT2
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BU of 3bt2 by Molmil
Structure of urokinase receptor, urokinase and vitronectin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ...
Authors:Huang, M.
Deposit date:2007-12-27
Release date:2008-03-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3E6P
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BU of 3e6p by Molmil
Crystal structure of human meizothrombin desF1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-PHENYLALANYL-N-[(1S)-4-{[(Z)-AMINO(IMINO)METHYL]AMINO}-1-(CHLOROACETYL)BUTYL]-L-PROLINAMIDE, Prothrombin, ...
Authors:Papaconstantinou, M.E, Gandhi, P, Chen, Z, Bah, A, Di Cera, E.
Deposit date:2008-08-15
Release date:2008-11-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Na(+) binding to meizothrombin desF1.
Cell.Mol.Life Sci., 65, 2008
3HN4
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Crystal structure of the NK2 fragment (28-289) of human hepatocyte growth factor/scatter factor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hepatocyte growth factor, ...
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
3K65
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Crystal Structure of Prethombin-2/Fragment-2 Complex
Descriptor: 1,4-BUTANEDIOL, Prothrombin
Authors:Adams, T.E, Huntington, J.A.
Deposit date:2009-10-08
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural transitions during prothrombin activation: On the importance of fragment 2.
Biochimie, 122, 2016
3KIV
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BU of 3kiv by Molmil
RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)
Descriptor: 6-AMINOHEXANOIC ACID, APOLIPOPROTEIN
Authors:Mochalkin, I, Tulinsky, A, Scanu, A.
Deposit date:1998-09-08
Release date:1999-05-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.
Biochemistry, 38, 1999
3LAQ
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BU of 3laq by Molmil
Structure-based engineering of species selectivity in the uPA-uPAR interaction
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator
Authors:Huang, M.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy.
J.Biol.Chem., 285, 2010

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