5ME8
| N-terminal domain of the human tumor suppressor ING5 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5 | Authors: | Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R. | Deposit date: | 2016-11-14 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark. J.Mol.Biol., 431, 2019
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5MTO
| N-terminal domain of the human tumor suppressor ING5 C19S mutant | Descriptor: | Inhibitor of growth protein 5, SODIUM ION, SULFATE ION | Authors: | Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J. | Deposit date: | 2017-01-10 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark. J.Mol.Biol., 431, 2019
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3O7A
| Crystal structure of PHF13 in complex with H3K4me3 | Descriptor: | GLYCEROL, H3K4ME3 HISTONE 11MER-PEPTIDE, PHD finger protein 13 variant, ... | Authors: | Bian, C.B, Lam, R, Xu, C, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2010-07-30 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. Elife, 5, 2016
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5A3N
| Crystal structure of human PLU-1 (JARID1B) in complex with KDOAM25a | Descriptor: | 1,2-ETHANEDIOL, 2-[[[2-[2-(dimethylamino)ethyl-ethyl-amino]-2-oxidanylidene-ethyl]amino]methyl]pyridine-4-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Srikannathasan, V, Johansson, C, Gileadi, C, Nuzzi, A, Ruda, G.F, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Brennan, P, Oppermann, U. | Deposit date: | 2015-06-02 | Release date: | 2015-07-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol, 24, 2017
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7CFQ
| Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ... | Authors: | Zhao, J, Zhang, X, Zang, J. | Deposit date: | 2020-06-27 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights into the recognition of histone H3Q5 serotonylation by WDR5. Sci Adv, 7, 2021
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5XMY
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5SVX
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9C0O
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4YHZ
| Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide | Descriptor: | Fab Heavy Chain, Fab Light Chain, GLYCEROL, ... | Authors: | Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S. | Deposit date: | 2015-02-27 | Release date: | 2016-02-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. Proc.Natl.Acad.Sci.USA, 113, 2016
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2V83
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2V89
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3MEA
| Crystal structure of the SGF29 in complex with H3K4me3 | Descriptor: | Histone H3, SAGA-associated factor 29 homolog | Authors: | Bian, C, Xu, C, Tempel, W, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2010-03-31 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
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4L58
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3ME9
| Crystal structure of SGF29 in complex with H3K4me3 peptide | Descriptor: | GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ... | Authors: | Bian, C, Tempel, W, Xu, C, Guo, Y, Dong, A, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2010-03-31 | Release date: | 2010-04-28 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. Embo J., 30, 2011
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5TDW
| Set3 PHD finger in complex with histone H3K4me3 | Descriptor: | SET domain-containing protein 3, SODIUM ION, ZINC ION, ... | Authors: | Andrews, F.H, Ali, M, Kutateladze, T.G. | Deposit date: | 2016-09-19 | Release date: | 2016-10-19 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Insight into Recognition of Methylated Histone H3K4 by Set3. J. Mol. Biol., 429, 2017
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4L7X
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4MZG
| Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | Authors: | Su, X, Ding, X, Li, H. | Deposit date: | 2013-09-30 | Release date: | 2014-03-26 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
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3N9L
| ceKDM7A from C.elegans, complex with H3K4me3 peptide and NOG | Descriptor: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | Authors: | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | Deposit date: | 2010-05-31 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Cell Res., 20, 2010
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3N9O
| ceKDM7A from C.elegans, complex with H3K4me3 peptide, H3K9me2 peptide and NOG | Descriptor: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | Authors: | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | Deposit date: | 2010-05-31 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.309 Å) | Cite: | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Cell Res., 20, 2010
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3N9Q
| ceKDM7A from C.elegans, complex with H3K4me3 peptide, H3K27me2 peptide and NOG | Descriptor: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | Authors: | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | Deposit date: | 2010-05-31 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Cell Res., 20, 2010
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3MP1
| Complex structure of Sgf29 and trimethylated H3K4 | Descriptor: | ACETATE ION, H3K4me3 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, ... | Authors: | Li, J, Ruan, J, Wu, M, Xue, X, Zang, J. | Deposit date: | 2010-04-24 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
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5YC4
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3N9N
| ceKDM7A from C.elegans, complex with H3K4me3K9me2 peptide and NOG | Descriptor: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | Authors: | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | Deposit date: | 2010-05-31 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Cell Res., 20, 2010
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3N9P
| ceKDM7A from C.elegans, complex with H3K4me3K27me2 peptide and NOG | Descriptor: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | Authors: | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | Deposit date: | 2010-05-31 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.388 Å) | Cite: | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Cell Res., 20, 2010
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3KQI
| crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | Descriptor: | CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ... | Authors: | Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2019-02-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation. J.Biol.Chem., 285, 2010
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