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2Q8D
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Crystal structure of JMJ2D2A in ternary complex with histone H3-K36me2 and succinate
Descriptor: HISTONE 3 peptide, JmjC domain-containing histone demethylation protein 3A, NICKEL (II) ION, ...
Authors:Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
2Q8E
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Specificity and Mechanism of JMJD2A, a Trimethyllysine-Specific Histone Demethylase
Descriptor: JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ...
Authors:Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
2Q8F
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BU of 2q8f by Molmil
Structure of pyruvate dehydrogenase kinase isoform 1
Descriptor: POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1
Authors:Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
Deposit date:2007-06-10
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
2Q8G
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Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545
Descriptor: 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1
Authors:Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
Deposit date:2007-06-10
Release date:2007-07-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
2Q8H
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Structure of pyruvate dehydrogenase kinase isoform 1 in complex with dichloroacetate (DCA)
Descriptor: DICHLORO-ACETIC ACID, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1
Authors:Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
Deposit date:2007-06-10
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
2Q8I
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Pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug radicicol
Descriptor: DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, GLYCEROL, ...
Authors:Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
Deposit date:2007-06-10
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
2Q8J
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Crystal Structure of the complex of C-lobe of bovine lactoferrin with Mannitol and Mannose at 2.7 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ...
Authors:Mir, R, Jain, R, Sinha, M, Singh, N, Sharma, S, Kaur, P, Bhushan, A, Singh, T.P.
Deposit date:2007-06-11
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structure of the complex of C-lobe of bovine lactoferrin with Mannitol and Mannose at 2.7 A resolution
To be Published
2Q8K
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The crystal structure of Ebp1
Descriptor: GLYCEROL, Proliferation-associated protein 2G4, SULFATE ION
Authors:Kowalinski, E, Bange, G, Wild, K, Sinning, I.
Deposit date:2007-06-11
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions.
Febs Lett., 581, 2007
2Q8L
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BU of 2q8l by Molmil
Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum
Descriptor: Orotidine-monophosphate-decarboxylase, PHOSPHATE ION
Authors:Liu, Y, Lau, W, Lew, J, Amani, M, Hui, R, Pai, E.F, Structural Genomics Consortium (SGC)
Deposit date:2007-06-11
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum.
To be Published
2Q8M
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BU of 2q8m by Molmil
T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
Authors:Hines, J.K, Kruesel, C.E, Fromm, H.J, Honzatko, R.B.
Deposit date:2007-06-11
Release date:2007-06-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of Inhibited Fructose-1,6-bisphosphatase from Escherichia coli: DISTINCT ALLOSTERIC INHIBITION SITES FOR AMP AND GLUCOSE 6-PHOSPHATE AND THE CHARACTERIZATION OF A GLUCONEOGENIC SWITCH.
J.Biol.Chem., 282, 2007
2Q8N
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BU of 2q8n by Molmil
Crystal structure of Glucose-6-phosphate isomerase (EC 5.3.1.9) (TM1385) from Thermotoga maritima at 1.82 A resolution
Descriptor: CHLORIDE ION, Glucose-6-phosphate isomerase, NONAETHYLENE GLYCOL, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2007-06-11
Release date:2007-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of Glucose-6-phosphate isomerase (EC 5.3.1.9) (TM1385) from Thermotoga maritima at 1.82 A resolution
To be published
2Q8O
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BU of 2q8o by Molmil
crystal structure of mouse GITR ligand dimer
Descriptor: GITR ligand
Authors:Zhaocai, Z, Yukiko, T.
Deposit date:2007-06-11
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for ligand-mediated mouse GITR activation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Q8P
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BU of 2q8p by Molmil
Crystal Structure of selenomethionine labelled S. aureus IsdE complexed with heme
Descriptor: Iron-regulated surface determinant E, PROTOPORPHYRIN IX CONTAINING FE
Authors:Grigg, J.C, Murphy, M.E.
Deposit date:2007-06-11
Release date:2007-07-31
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Heme Coordination by Staphylococcus aureus IsdE.
J.Biol.Chem., 282, 2007
2Q8Q
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BU of 2q8q by Molmil
Crystal Structure of S. aureus IsdE complexed with heme
Descriptor: Iron-regulated surface determinant E, PROTOPORPHYRIN IX CONTAINING FE
Authors:Grigg, J.C, Murphy, M.E.
Deposit date:2007-06-11
Release date:2007-07-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Heme Coordination by Staphylococcus aureus IsdE.
J.Biol.Chem., 282, 2007
2Q8R
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BU of 2q8r by Molmil
Structural and Functional Characterization of CC Chemokine CCL14
Descriptor: CCL14
Authors:Blain, K.Y.
Deposit date:2007-06-11
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural and Functional Characterization of CC Chemokine CCL14
Biochemistry, 46, 2007
2Q8S
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BU of 2q8s by Molmil
X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist
Descriptor: (2S)-3-{4-[3-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)PROPYL]PHENYL}-2-(1H-PYRROL-1-YL)PROPANOIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Ohren, J.F.
Deposit date:2007-06-11
Release date:2008-10-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
Bioorg.Med.Chem., 16, 2008
2Q8T
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BU of 2q8t by Molmil
Crystal Structure of the CC chemokine CCL14
Descriptor: CCL14
Authors:Blain, K.Y.
Deposit date:2007-06-11
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural and Functional Characterization of CC Chemokine CCL14
Biochemistry, 46, 2007
2Q8U
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BU of 2q8u by Molmil
CRYSTAL STRUCTURE OF MRE11 FROM THERMOTOGA MARITIMA MSB8 (TM1635) AT 2.20 A RESOLUTION
Descriptor: Exonuclease, putative
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2007-06-11
Release date:2007-06-26
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
J.Mol.Biol., 397, 2010
2Q8V
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BU of 2q8v by Molmil
NblA protein from T. vulcanus crystallized with urea
Descriptor: NblA protein, UREA
Authors:Adir, N, Dines, M.
Deposit date:2007-06-12
Release date:2008-07-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural, Functional, and Mutational Analysis of the NblA Protein Provides Insight into Possible Modes of Interaction with the Phycobilisome
J.Biol.Chem., 283, 2008
2Q8W
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BU of 2q8w by Molmil
Crystal structure of PAP-S1aci, a pokeweed antiviral protein from seeds of Phytolacca acinosa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, POKEWEED ANTIVIRAL PROTEIN
Authors:Hogg, T, Hilgenfeld, R.
Deposit date:2007-06-12
Release date:2008-06-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The complete covalent structure and 1.7 A crystal structure of PAP-S1aci reveals a RIP glycoprotein with multiple Asn-GlcNAc modifications
To be Published
2Q8X
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BU of 2q8x by Molmil
The high-resolution crystal structure of ixt6, a thermophilic, intracellular xylanase from G. stearothermophilus
Descriptor: GLYCEROL, SODIUM ION, intra-cellular xylanase
Authors:Solomon, V, Teplitsky, A, Gilboa, R, Zolotnitsky, G, Golan, G, Reiland, V, Moryles, S, Shoham, Y, Shoham, G.
Deposit date:2007-06-12
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure-specificity relationships of an intracellular xylanase from Geobacillus stearothermophilus
Acta Crystallogr.,Sect.D, 63, 2007
2Q8Y
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BU of 2q8y by Molmil
Structural insight into the enzymatic mechanism of the phophothreonine lyase
Descriptor: 27.5 kDa virulence protein, Mitogen-activated protein kinase 7
Authors:Zhu, Y.-Q, Wang, D.-C, Shao, F.
Deposit date:2007-06-12
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase
Mol.Cell, 28, 2007
2Q8Z
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Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase complexed with 6-amino-UMP
Descriptor: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 6-AMINOURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F.
Deposit date:2007-06-12
Release date:2008-01-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
2Q91
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Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor
Descriptor: CALCIUM ION, S100A4 Metastasis Factor
Authors:Malashkevich, V.N, Knight, D, Ramagopal, U.A, Almo, S.C, Bresnick, A.R.
Deposit date:2007-06-12
Release date:2008-02-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of Ca(2+)-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA.
Biochemistry, 47, 2008
2Q92
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BU of 2q92 by Molmil
E. coli methionine aminopeptidase Mn-form with inhibitor B23
Descriptor: 5-(2-NITROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ...
Authors:Ye, Q.-Z.
Deposit date:2007-06-12
Release date:2008-01-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007

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