9LE5
 
 | | Focused asymmetric unit of UCC118 Rool RNA | | Descriptor: | UCC118 Rool RNA | | Authors: | Zhang, K, Li, S. | | Deposit date: | 2025-01-07 | | Release date: | 2025-09-10 | | Last modified: | 2025-10-29 | | Method: | ELECTRON MICROSCOPY (2.58 Å) | | Cite: | Structural insights into higher-order natural RNA-only multimers.
Nat.Struct.Mol.Biol., 32, 2025
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9LE3
 | | Consensus map of UCC118 Rool RNA | | Descriptor: | UCC118 Rool RNA | | Authors: | Zhang, K, Li, S. | | Deposit date: | 2025-01-07 | | Release date: | 2025-09-10 | | Last modified: | 2025-10-29 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structural insights into higher-order natural RNA-only multimers.
Nat.Struct.Mol.Biol., 32, 2025
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9LE6
 | | Composite map of UCC118 Rool RNA | | Descriptor: | UCC118 Rool RNA | | Authors: | Zhang, K, Li, S. | | Deposit date: | 2025-01-07 | | Release date: | 2025-09-10 | | Last modified: | 2025-10-29 | | Method: | ELECTRON MICROSCOPY (2.58 Å) | | Cite: | Structural insights into higher-order natural RNA-only multimers.
Nat.Struct.Mol.Biol., 32, 2025
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9M78
 | | Consensus map of UCC118 Rool RNA at 2.26-angstrom resolution | | Descriptor: | UCC118 Rool RNA | | Authors: | Zhang, S, Yi, R, An, L, Li, S, Zhang, K. | | Deposit date: | 2025-03-10 | | Release date: | 2025-09-10 | | Last modified: | 2025-10-29 | | Method: | ELECTRON MICROSCOPY (2.26 Å) | | Cite: | Structural insights into higher-order natural RNA-only multimers.
Nat.Struct.Mol.Biol., 32, 2025
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9HH2
 | | Crystal structure of the family S1_19 carrageenan sulfatase ZgCgsA from Zobellia galactanivorans in complex with hybrid a-i-neocarratetraose | | Descriptor: | 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, BROMIDE ION, CALCIUM ION, ... | | Authors: | Chevenier, A, Czjzek, M, Michel, G, Ficko-Blean, E. | | Deposit date: | 2024-11-20 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structure, function and catalytic mechanism of the carrageenan-sulfatases from the marine bacterium Zobellia galactanivorans Dsij T.
Carbohydr Polym, 358, 2025
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9I0W
 | | Structure of human PD-L1 in complex with clinically evaluated inhibitor | | Descriptor: | (3~{R})-1-[[7-(iminomethyl)-2-[2-methyl-3-[2-methyl-3-[[3-[[(3~{R})-3-oxidanylpyrrolidin-1-yl]methyl]-1,7-naphthyridin-8-yl]amino]phenyl]phenyl]-1,3-benzoxazol-5-yl]methyl]pyrrolidine-3-carboxylic acid, Programmed cell death 1 ligand 1 | | Authors: | Plewka, J, Golebiowska-Mendroch, K, Slota, A, Magiera-Mularz, K. | | Deposit date: | 2025-01-15 | | Release date: | 2025-06-18 | | Last modified: | 2025-07-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of Clinically Evaluated Small-Molecule Inhibitors of PD-L1 for Immunotherapy.
Acs Med.Chem.Lett., 16, 2025
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4V6I
 | | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... | | Authors: | Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | Deposit date: | 2010-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (8.8 Å) | | Cite: | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4WBV
 | | Crystal structure of a prion peptide | | Descriptor: | PrP peptide | | Authors: | Yu, L, Lee, S.-J, Yee, V. | | Deposit date: | 2014-09-03 | | Release date: | 2015-05-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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4WAN
 | | Crystal structure of Msl5 protein in complex with RNA at 1.8 A | | Descriptor: | ACETATE ION, Branchpoint-bridging protein, GLYCEROL, ... | | Authors: | Jacewicz, A, Smith, P, Chico, L, Schwer, B, Shuman, S. | | Deposit date: | 2014-08-29 | | Release date: | 2014-12-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs.
Rna, 21, 2015
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8ODZ
 | | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1). | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ... | | Authors: | Felix, J, Bloch, Y, Savvides, S.N. | | Deposit date: | 2023-03-10 | | Release date: | 2024-02-07 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
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9HZL
 | | High resolution cryo-EM structure of human complex III in mitochondria | | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | Authors: | Nguyen, M.D, Khajawa, A, Rorbach, J. | | Deposit date: | 2025-01-14 | | Release date: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Structural basis for late maturation steps of mitochondrial respiratory chain complex IV within the human respirasome
To Be Published
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4WHK
 | | A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1 | | Descriptor: | C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1 | | Authors: | Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S. | | Deposit date: | 2014-09-23 | | Release date: | 2014-12-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
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4WXB
 | | Crystal Structure of Serine Hydroxymethyltransferase from Streptococcus thermophilus | | Descriptor: | CACODYLATE ION, CITRIC ACID, GLYCEROL, ... | | Authors: | Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. | | Deposit date: | 2014-11-13 | | Release date: | 2015-02-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4WJ2
 | | Mycobacterial protein | | Descriptor: | Antigen MTB48 | | Authors: | Solomonson, M, Strynadka, N.C.J. | | Deposit date: | 2014-09-29 | | Release date: | 2015-02-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of EspB from the ESX-1 type VII secretion system and insights into its export mechanism.
Structure, 23, 2015
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8JYX
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9JPI
 | | The complex structure of DHAD with aspterric acid (AA). | | Descriptor: | Aspterric Acid, Dihydroxy-acid dehydratase, chloroplastic, ... | | Authors: | Zhou, J, Zang, X, Tang, Y, Yan, Y. | | Deposit date: | 2024-09-26 | | Release date: | 2024-12-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Bases of Dihydroxy Acid Dehydratase Inhibition and Biodesign for Self-Resistance.
Biodes Res, 6, 2024
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4WVC
 | | Crystal structure of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8 in complex with Tris and D-glycerate | | Descriptor: | (2R)-2,3-DIHYDROXYPROPANOIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | Authors: | Miyazaki, T, Ichikawa, M, Nishikawa, A, Tonozuka, T. | | Deposit date: | 2014-11-05 | | Release date: | 2015-03-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure and substrate-binding mode of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8.
J.Struct.Biol., 190, 2015
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4WKW
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4X2L
 | | Crystal structure of human BACE-1 bound to Compound 6 | | Descriptor: | (4S)-4-(2,4-difluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... | | Authors: | Vajdos, F.F, Parris, K. | | Deposit date: | 2014-11-26 | | Release date: | 2015-03-04 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design.
J.Med.Chem., 58, 2015
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4X0C
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9J1M
 | | KU13-bond Mycobacterium tuberculosis 70S ribosome | | Descriptor: | (2~{R},3~{R},4~{R},5~{R},8~{R},10~{R},11~{R},12~{S},13~{S},14~{R})-11-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-4-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4-bis(oxidanyl)-5-[[4-(4-pyridin-4-yl-1,2,3-triazol-1-yl)phenyl]methoxy]oxan-2-yl]oxy-13-[(2~{R},4~{R},5~{S},6~{S})-4-methoxy-4,6-dimethyl-5-oxidanyl-oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-3,10-bis(oxidanyl)-1-oxa-6-azacyclopentadecan-15-one, 16S rRNA, 23S rRNA, ... | | Authors: | Nishihara, D, Fujino, M, Tanaka, Y, Yokoyama, T. | | Deposit date: | 2024-08-05 | | Release date: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (2.33 Å) | | Cite: | Creation of a macrolide antibiotic against non-tuberculous Mycobacterium using late-stage boron-mediated aglycon delivery.
Sci Adv, 11, 2025
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4X91
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4WIQ
 | | The structure of Murine alpha-Dystroglycan T190M mutant N-terminal domain. | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Dystroglycan | | Authors: | Brancaccio, A, Lamba, D, Cassetta, A, Bozzi, M, Covaceuszach, S, Sciandra, F, Bigotti, M.G. | | Deposit date: | 2014-09-26 | | Release date: | 2015-05-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | The Structure of the T190M Mutant of Murine alpha-Dystroglycan at High Resolution: Insight into the Molecular Basis of a Primary Dystroglycanopathy.
Plos One, 10, 2015
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4X55
 | | Structure of the class D Beta-Lactamase OXA-225 K82D in Acyl-Enzyme Complex with Ceftazidime | | Descriptor: | 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, Beta-lactamase OXA-225 | | Authors: | Clasman, J.R, June, C.M, Powers, R.A, Leonard, D.A. | | Deposit date: | 2014-12-04 | | Release date: | 2015-03-11 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.941 Å) | | Cite: | Structural Basis of Activity against Aztreonam and Extended Spectrum Cephalosporins for Two Carbapenem-Hydrolyzing Class D beta-Lactamases from Acinetobacter baumannii.
Biochemistry, 54, 2015
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8EDA
 | | An alternating AT dodecamer benzimidazole (DB1476) complex | | Descriptor: | 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | Authors: | Ogbonna, E.N, Wilson, W.D. | | Deposit date: | 2022-09-03 | | Release date: | 2023-02-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
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