4WIQ
The structure of Murine alpha-Dystroglycan T190M mutant N-terminal domain.
Summary for 4WIQ
Entry DOI | 10.2210/pdb4wiq/pdb |
Related | 1U2C |
Descriptor | Dystroglycan, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | mutant, dystroglycanopathy, structural protein |
Biological source | Mus musculus (Mouse) |
Cellular location | Alpha-dystroglycan: Secreted, extracellular space . Beta-dystroglycan: Cell membrane ; Single-pass type I membrane protein : Q62165 |
Total number of polymer chains | 1 |
Total formula weight | 28669.06 |
Authors | Brancaccio, A.,Lamba, D.,Cassetta, A.,Bozzi, M.,Covaceuszach, S.,Sciandra, F.,Bigotti, M.G. (deposition date: 2014-09-26, release date: 2015-05-13, Last modification date: 2024-01-10) |
Primary citation | Bozzi, M.,Cassetta, A.,Covaceuszach, S.,Bigotti, M.G.,Bannister, S.,Hubner, W.,Sciandra, F.,Lamba, D.,Brancaccio, A. The Structure of the T190M Mutant of Murine alpha-Dystroglycan at High Resolution: Insight into the Molecular Basis of a Primary Dystroglycanopathy. Plos One, 10:e0124277-e0124277, 2015 Cited by PubMed: 25932631DOI: 10.1371/journal.pone.0124277 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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