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2L3R
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BU of 2l3r by Molmil
NMR structure of UHRF1 Tandem Tudor Domains in a complex with Histone H3 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3
Authors:Nady, N, Lemak, A, Fares, C, Gutmanas, A, Avvakumov, G, Xue, S, Arrowsmith, C, Structural Genomics Consortium (SGC)
Deposit date:2010-09-21
Release date:2011-04-13
Last modified:2025-03-26
Method:SOLUTION NMR
Cite:Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein.
J.Biol.Chem., 286, 2011
6XGC
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BU of 6xgc by Molmil
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
Descriptor: 1C4 Fab heavy chain, 1C4 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Qiu, Y, Zhou, Y.
Deposit date:2020-06-17
Release date:2021-03-10
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021
2RVM
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BU of 2rvm by Molmil
Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail
Descriptor: Chromobox protein homolog 5
Authors:Kawaguchi, A, Nishimura, Y.
Deposit date:2015-12-18
Release date:2016-03-16
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2NDG
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BU of 2ndg by Molmil
Solution NMR structures of AF9 yeats domain in complex with histone H3 crotonylation at K18
Descriptor: Histone H3 peptide, Protein AF-9
Authors:Zeng, L, Zhou, M.
Deposit date:2016-05-19
Release date:2016-09-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
2RVL
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BU of 2rvl by Molmil
Solution structure of the chromodomain of HP1alpha with the N-terminal tail
Descriptor: Chromobox protein homolog 5
Authors:Kawaguchi, A, Nishimura, Y.
Deposit date:2015-12-18
Release date:2016-03-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
5JJ0
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BU of 5jj0 by Molmil
Structure of G9a SET-domain with Histone H3K9M peptide and excess SAH
Descriptor: Histone H3K9M mutant peptide, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
Authors:Jayaram, H, Bellon, S.F, Poy, F.
Deposit date:2016-04-22
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proc.Natl.Acad.Sci.USA, 113, 2016
3U5N
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BU of 3u5n by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-20)K9me3K14ac histone peptide
Descriptor: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2011-10-11
Release date:2012-01-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Poised Chromatin Platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
3U5P
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BU of 3u5p by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone peptide
Descriptor: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2011-10-11
Release date:2012-01-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
2L5U
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BU of 2l5u by Molmil
Structure of the first PHD finger (PHD1) from CHD4 (Mi2b)
Descriptor: Chromodomain-helicase-DNA-binding protein 4, ZINC ION
Authors:Mansfield, R.E, Kwan, A.H, Mackay, J.P.
Deposit date:2010-11-08
Release date:2011-01-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9
J.Biol.Chem., 286, 2011
4XZQ
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BU of 4xzq by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
Deposit date:2015-02-04
Release date:2015-10-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
3IV2
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BU of 3iv2 by Molmil
Crystal structure of mature apo-Cathepsin L C25A mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin L1, GLYCEROL, ...
Authors:Adams-Cioaba, M.A, Krupa, J.C, Mort, J.S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J.
Deposit date:2009-08-31
Release date:2010-03-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the recognition and cleavage of histone H3 by cathepsin L.
Nat Commun, 2, 2011
4Z2M
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BU of 4z2m by Molmil
Crystal structure of human SPT16 Mid-AID/H3-H4 tetramer FACT Histone complex
Descriptor: FACT complex subunit SPT16, Histone H3.1, Histone H4
Authors:Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K.
Deposit date:2015-03-30
Release date:2016-03-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.981 Å)
Cite:Integrated molecular mechanism directing nucleosome reorganization by human FACT.
Genes Dev., 30, 2016
8TXU
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BU of 8txu by Molmil
Fab 3864-10 in complex with influenza HA H3-SING16
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 3864-10 Heavy Chain, Fab 3864-10 Light Chain, ...
Authors:Morano, N.C, Shapiro, L.
Deposit date:2023-08-24
Release date:2024-09-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Fab 3864-6 in complex with influenza HA H3-VIC11
To Be Published
5DX0
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BU of 5dx0 by Molmil
Crystal structure of CARM1, sinefungin, and H3 peptide (R17)
Descriptor: GLYCEROL, H3 peptide, Histone-arginine methyltransferase CARM1, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-23
Release date:2015-11-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
5XM2
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BU of 5xm2 by Molmil
Human N-terminal domain of FACT complex subunit SPT16
Descriptor: DI(HYDROXYETHYL)ETHER, FACT complex subunit SPT16, GLYCEROL
Authors:Xu, S, Li, H, Dou, Y, Chen, Y, Jiang, H, Lu, D, Wang, M, Su, D.
Deposit date:2017-05-12
Release date:2018-05-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:The structural basis of human Spt16 N-terminal domain interaction with histone (H3-H4)2tetramer.
Biochem.Biophys.Res.Commun., 508, 2019
4YS3
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BU of 4ys3 by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
Deposit date:2015-03-16
Release date:2015-10-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
4Z66
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BU of 4z66 by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
Deposit date:2015-04-03
Release date:2015-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
6OI3
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BU of 6oi3 by Molmil
Crystal structure of human WDR5 in complex with monomethyl H3R2 peptide
Descriptor: GLYCEROL, Monomethyl H3R2 peptide, SULFATE ION, ...
Authors:Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
Deposit date:2019-04-08
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
2VXP
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BU of 2vxp by Molmil
The fourth FAS1 domain structure of human Bigh3
Descriptor: TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3
Authors:Yoo, J.-H, Cho, H.-S.
Deposit date:2008-07-08
Release date:2009-07-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structural Analysis of the Fas1 Domain 4 of Big-H3 for Relationship with Corneal Dystrophy
To be Published
3DB3
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BU of 3db3 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-05-30
Release date:2008-09-16
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
7EIF
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BU of 7eif by Molmil
Crystal structure of GAS41 YEATS domain
Descriptor: GLYCEROL, YEATS domain-containing protein 4
Authors:Kikuchi, M, Umehara, T.
Deposit date:2021-03-30
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
2XL3
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BU of 2xl3 by Molmil
WDR5 IN COMPLEX WITH AN RBBP5 PEPTIDE AND HISTONE H3 PEPTIDE
Descriptor: GLYCEROL, HISTONE H3.1, RETINOBLASTOMA-BINDING PROTEIN 5, ...
Authors:Odho, Z, Southall, S.M, Wilson, J.R.
Deposit date:2010-07-19
Release date:2010-08-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Characterisation of a Novel Wdr5 Binding Site that Recruits Rbbp5 Through a Conserved Motif and Enhances Methylation of H3K4 by Mll1.
J.Biol.Chem., 285, 2010
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
Descriptor: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
Authors:Chen, S, Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
5SZC
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BU of 5szc by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with monomethylated K4 and acetylated K14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.193 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
2XYI
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BU of 2xyi by Molmil
Crystal Structure of Nurf55 in complex with a H4 peptide
Descriptor: DI(HYDROXYETHYL)ETHER, HISTONE H4, PROBABLE HISTONE-BINDING PROTEIN CAF1, ...
Authors:Stirnimann, C.U, Nowak, A.J, Mueller, C.W.
Deposit date:2010-11-17
Release date:2011-05-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Chromatin-Modifying Complex Component Nurf55/P55 Associates with Histones H3, H4 and Polycomb Repressive Complex 2 Subunit Su(Z)12 Through Partially Overlapping Binding Sites.
J.Biol.Chem., 286, 2011

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