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2HBO
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Crystal structure of a thioesterase superfamily protein (cc_3309) from caulobacter vibrioides at 1.85 A resolution
Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Hypothetical protein (np_422103.1)
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-06-14
Release date:2006-08-08
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of hypothetical protein (np_422103.1) from Caulobacter crescentus at 1.85 A resolution
To be published
2HBP
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Solution Structure of Sla1 Homology Domain 1
Descriptor: Cytoskeleton assembly control protein SLA1
Authors:Overduin, M, Mahadev, R.K.
Deposit date:2006-06-14
Release date:2007-04-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of Sla1p homology domain 1 and interaction with the NPFxD endocytic internalization motif.
Embo J., 26, 2007
2HBQ
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Crystal structure of wildtype human caspase-1 in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2HBR
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Crystal structure of human caspase-1 (Arg286->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2HBS
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S
Descriptor: HEMOGLOBIN S (DEOXY), ALPHA CHAIN, BETA CHAIN, ...
Authors:Harrington, D.J, Adachi, K, Royer Junior, W.E.
Deposit date:1997-05-06
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The high resolution crystal structure of deoxyhemoglobin S.
J.Mol.Biol., 272, 1997
2HBT
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Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Evdokimov, A.G, Walter, R.L, Mekel, M, Pokross, M.E, Kawamoto, R, Boyer, A.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor
To be Published
2HBU
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Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Evdokimov, A.G, Walter, R.L, Mekel, M, Pokross, M.E, Kawamoto, R, Boyer, A.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor
To be Published
2HBV
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Crystal Structure of alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde-Decarboxylase (ACMSD)
Descriptor: 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, MAGNESIUM ION, ZINC ION
Authors:Martynowski, D, Eyobo, Y, Li, T, Yang, K, Liu, A, Zhang, H.
Deposit date:2006-06-14
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde Decarboxylase: Insight into the Active Site and Catalytic Mechanism of a Novel Decarboxylation Reaction.
Biochemistry, 45, 2006
2HBW
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Crystal structure of a putative endopeptidase (ava_3396) from anabaena variabilis atcc 29413 at 1.05 A resolution
Descriptor: ACETATE ION, NLP/P60 protein, UNKNOWN LIGAND
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-06-14
Release date:2006-08-08
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural Basis of Murein Peptide Specificity of a gamma-D-Glutamyl-L-Diamino Acid Endopeptidase.
Structure, 17, 2009
2HBX
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Crystal Structure of alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde-Decarboxylase (ACMSD)
Descriptor: 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, COBALT (II) ION
Authors:Martynowski, D, Eyobo, Y, Li, T, Yang, K, Liu, A, Zhang, H.
Deposit date:2006-06-14
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde Decarboxylase: Insight into the Active Site and Catalytic Mechanism of a Novel Decarboxylation Reaction.
Biochemistry, 45, 2006
2HBY
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Crystal structure of human caspase-1 (Glu390->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2HBZ
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BU of 2hbz by Molmil
Crystal structure of human caspase-1 (Arg286->Ala, Glu390->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, PHQ-VAD-fluoromethylketone inhibitor
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2HC0
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Structure of HIV protease 6X mutant in complex with AB-2.
Descriptor: BROMIDE ION, Protease, [1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL (1R,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YLCARBAMATE
Authors:Heaslet, H, Brik, A, Lin, Y.-C, Elder, J.H, Stout, C.D.
Deposit date:2006-06-14
Release date:2007-06-26
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of HIV Protease 6X Mutant in complex with AB-2
To be Published
2HC1
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Engineered catalytic domain of protein tyrosine phosphatase HPTPbeta.
Descriptor: ACETATE ION, CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta
Authors:Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
2HC2
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Engineered protein tyrosine phosphatase beta catalytic domain
Descriptor: MAGNESIUM ION, Receptor-type tyrosine-protein phosphatase beta, SODIUM ION
Authors:Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M.
Deposit date:2006-06-15
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
2HC4
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Crystal structure of the LBD of VDR of Danio rerio in complex with calcitriol
Descriptor: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, SRC-1 from Nuclear receptor coactivator 1, Vitamin D receptor
Authors:Ciesielski, F, Rochel, N, Moras, D.
Deposit date:2006-06-15
Release date:2007-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation
J.Steroid Biochem.Mol.Biol., 103, 2007
2HC5
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Solution NMR Structure of Protein yvyC from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR482.
Descriptor: Hypothetical protein yvyC
Authors:Eletsky, A, Liu, G, Atreya, H.S, Sukumaran, D.K, Wang, D, Cunningham, K, Janjua, H, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-06-15
Release date:2006-08-15
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:NMR structure of protein YvyC from Bacillus subtilis reveals unexpected structural similarity between two PFAM families.
Proteins, 76, 2009
2HC7
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2'-selenium-T A-DNA [G(TSe)GTACAC]
Descriptor: 5'-D(*GP*(2ST)P*GP*TP*AP*CP*AP*C)-3'
Authors:Jiang, J, Sheng, J, Huang, Z.
Deposit date:2006-06-15
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of 2'-Selenium modified T A-DNA G(TSe)GTACAC
TO BE PUBLISHED
2HC8
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BU of 2hc8 by Molmil
Structure of the A. fulgidus CopA A-domain
Descriptor: Cation-transporting ATPase, P-type
Authors:Sazinsky, M.H, Agawal, S, Arguello, J.M, Rosenzweig, A.C.
Deposit date:2006-06-15
Release date:2006-09-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of the Actuator Domain from the Archaeoglobus fulgidus Cu(+)-ATPase(,).
Biochemistry, 45, 2006
2HC9
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Structure of Caenorhabditis elegans leucine aminopeptidase-zinc complex (LAP1)
Descriptor: BICARBONATE ION, GLYCEROL, Leucine aminopeptidase 1, ...
Authors:Zhan, C, Patskovsky, Y, Wengerter, B.C, Ramagopal, U, Milstein, S, Vidal, M, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-15
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure and Function of Caenorhabditis Elegans Leucine Aminopeptidase
To be Published
2HCA
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Crystal structure of bovine lactoferrin C-lobe liganded with Glucose at 2.8 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Mir, R, Prem Kumar, R, Ethayathulla, A.S, Singh, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2006-06-15
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of bovine lactoferrin C-lobe liganded with Glucose at 2.8 A resolution
To be Published
2HCB
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Structure of AMPPCP-bound DnaA from Aquifex aeolicus
Descriptor: Chromosomal replication initiator protein dnaA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Erzberger, J.P, Mott, M.L, Berger, J.M.
Deposit date:2006-06-15
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling.
Nat.Struct.Mol.Biol., 13, 2006
2HCC
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SOLUTION STRUCTURE OF THE HUMAN CHEMOKINE HCC-2, NMR, 30 STRUCTURES
Descriptor: HUMAN CHEMOKINE HCC-2
Authors:Sticht, H, Escher, S.E, Schweimer, K, Forssmann, W.G, Roesch, P, Adermann, K.
Deposit date:1998-07-03
Release date:1999-07-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype.
Biochemistry, 38, 1999
2HCD
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Crystal structure of the ligand binding domain of the Vitamin D nuclear receptor in complex with Gemini and a coactivator peptide
Descriptor: 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ...
Authors:Ciesielski, F, Rochel, N, Moras, D.
Deposit date:2006-06-16
Release date:2007-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation
J.Steroid Biochem.Mol.Biol., 103, 2007
2HCF
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Crystal structure of hydrolase haloacid dehalogenase-like family (np_662590.1) from Chlorobium tepidum TLS at 1.80 A resolution
Descriptor: CHLORIDE ION, Hydrolase, haloacid dehalogenase-like family, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-06-16
Release date:2006-08-15
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of hydrolase haloacid dehalogenase-like family (np_662590.1) from Chlorobium tepidum TLS at 1.80 A resolution
To be published

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