2FUG
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2FZS
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2FZJ
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![BU of 2fzj by Molmil](/molmil-images/mine/2fzj) | New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives | Descriptor: | 2,4-DIAMINO-5-[3',4'-DIMETHOXY-5'-(5-CARBOXYL-1-PENTYNYL)]BENZYL PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cody, V, Pace, J, Chisum, K, Rosowsky, A. | Deposit date: | 2006-02-09 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins, 65, 2006
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2FVN
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2FNC
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![BU of 2fnc by Molmil](/molmil-images/mine/2fnc) | Thermotoga maritima maltotriose binding protein bound with maltotriose. | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose ABC transporter, periplasmic maltose-binding protein | Authors: | Cuneo, M.J, Changela, A. | Deposit date: | 2006-01-10 | Release date: | 2007-01-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The
crystal structure of redundant maltotriose binding proteins from the
thermophile Thermotoga maritima To be Published
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2HEO
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![BU of 2heo by Molmil](/molmil-images/mine/2heo) | General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers. | Descriptor: | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1 | Authors: | Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P. | Deposit date: | 2006-06-21 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers. J.Am.Chem.Soc., 128, 2006
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2H7T
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2GPL
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![BU of 2gpl by Molmil](/molmil-images/mine/2gpl) | TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors | Descriptor: | BENZYL [12-(2-AMINO-2-OXOETHYL)-4-NITRO-10,13-DIOXO-15-[(PROPYLAMINO)CARBONYL]-2-OXA-11,14-DIAZATRICYCLO[15 .2.2.1~3,7~]DOCOSA-1(19),3(22),4,6,17,20-HEXAEN-9-YL]CARBAMATE, Proteasome component C1, Proteasome component C11, ... | Authors: | Groll, M, Goetz, M, Kaiser, M, Weyher, E, Moroder, M. | Deposit date: | 2006-04-18 | Release date: | 2006-07-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome. Chem.Biol., 13, 2006
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2GT6
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![BU of 2gt6 by Molmil](/molmil-images/mine/2gt6) | Solution structure of Human Cu(I) Sco1 | Descriptor: | COPPER (I) ION, SCO1 protein homolog, mitochondrial | Authors: | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-04-27 | Release date: | 2006-06-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GXA
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2H35
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![BU of 2h35 by Molmil](/molmil-images/mine/2h35) | Solution structure of Human normal adult hemoglobin | Descriptor: | Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fan, J.S, Yang, D. | Deposit date: | 2006-05-22 | Release date: | 2006-11-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A new strategy for structure determination of large proteins in solution without deuteration Nat.Methods, 3, 2006
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1D3B
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![BU of 1d3b by Molmil](/molmil-images/mine/1d3b) | CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION | Descriptor: | CITRIC ACID, GLYCEROL, PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEIN B), ... | Authors: | Kambach, C, Walke, S, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | Deposit date: | 1998-12-22 | Release date: | 1999-12-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell(Cambridge,Mass.), 96, 1999
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2HC7
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![BU of 2hc7 by Molmil](/molmil-images/mine/2hc7) | 2'-selenium-T A-DNA [G(TSe)GTACAC] | Descriptor: | 5'-D(*GP*(2ST)P*GP*TP*AP*CP*AP*C)-3' | Authors: | Jiang, J, Sheng, J, Huang, Z. | Deposit date: | 2006-06-15 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of 2'-Selenium modified T A-DNA G(TSe)GTACAC TO BE PUBLISHED
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2H1L
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2HRQ
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![BU of 2hrq by Molmil](/molmil-images/mine/2hrq) | Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Soman (GD) | Descriptor: | (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, ... | Authors: | Fleming, C.D, Redinbo, M.R. | Deposit date: | 2006-07-20 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun. Biochemistry, 46, 2007
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2HIL
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![BU of 2hil by Molmil](/molmil-images/mine/2hil) | Structure of the Neisseria gonorrhoeae Type IV pilus filament from x-ray crystallography and electron cryomicroscopy | Descriptor: | Fimbrial protein, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, alpha-D-galactopyranose-(1-3)-2,4-bisacetamido-2,4-dideoxy-beta-D-glucopyranose | Authors: | Craig, L, Volkmann, N, Egelman, E.H, Tainer, J.A. | Deposit date: | 2006-06-29 | Release date: | 2006-09-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (12.5 Å) | Cite: | Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions. Mol.Cell, 23, 2006
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2HNB
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![BU of 2hnb by Molmil](/molmil-images/mine/2hnb) | Solution Structure of a bacterial holo-flavodoxin | Descriptor: | Protein mioC | Authors: | Hu, Y, Jin, C. | Deposit date: | 2006-07-12 | Release date: | 2006-09-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures and backbone dynamics of a flavodoxin MioC from Escherichia coli in both Apo- and Holo-forms: implications for cofactor binding and electron transfer J.Biol.Chem., 281, 2006
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2HLN
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![BU of 2hln by Molmil](/molmil-images/mine/2hln) | L-asparaginase from Erwinia carotovora in complex with glutamic acid | Descriptor: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, L-asparaginase | Authors: | Kravchenko, O.V, Kislitsin, Y.A, Popov, A.N, Nikonov, S.V, Kuranova, I.P. | Deposit date: | 2006-07-08 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-dimensional structures of L-asparaginase from Erwinia carotovora complexed with aspartate and glutamate. Acta Crystallogr.,Sect.D, 64, 2008
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2HLZ
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![BU of 2hlz by Molmil](/molmil-images/mine/2hlz) | Crystal Structure of human ketohexokinase | Descriptor: | Ketohexokinase, UNKNOWN ATOM OR ION | Authors: | Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-07-10 | Release date: | 2006-08-08 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of human ketohexokinase (CASP Target) To be Published
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2GBV
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![BU of 2gbv by Molmil](/molmil-images/mine/2gbv) | C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase | Descriptor: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M. | Deposit date: | 2006-03-11 | Release date: | 2007-01-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase J.Mol.Biol., 365, 2007
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2GSM
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![BU of 2gsm by Molmil](/molmil-images/mine/2gsm) | Catalytic Core (Subunits I and II) of Cytochrome c oxidase from Rhodobacter sphaeroides | Descriptor: | CADMIUM ION, CALCIUM ION, COPPER (II) ION, ... | Authors: | Qin, L, Hiser, C, Mulichak, A, Garavito, R.M, Ferguson-Miller, S. | Deposit date: | 2006-04-26 | Release date: | 2006-10-10 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GWE
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2H16
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![BU of 2h16 by Molmil](/molmil-images/mine/2h16) | Structure of human ADP-ribosylation factor-like 5 (ARL5) | Descriptor: | ADP-ribosylation factor-like protein 5A, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION | Authors: | Rabeh, W.M, Tempel, W, Yaniw, D, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-05-16 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human ADP-ribosylation factor-like 5 (ARL5) To be Published
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2HRA
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![BU of 2hra by Molmil](/molmil-images/mine/2hra) | Crystal structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA aminoacylation and nuclear export cofactor Arc1p reveal a novel function for an old fold | Descriptor: | Glutamyl-tRNA synthetase, cytoplasmic, IODIDE ION | Authors: | Simader, H, Hothorn, M, Suck, D. | Deposit date: | 2006-07-20 | Release date: | 2006-09-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA-aminoacylation and nuclear-export cofactor Arc1p reveal a novel function for an old fold. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2HRF
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![BU of 2hrf by Molmil](/molmil-images/mine/2hrf) | Solution Structure of Cu(I) P174L HSco1 | Descriptor: | COPPER (I) ION, SCO1 protein homolog, mitochondrial | Authors: | Banci, L, Bertini, I, Ciofi-Baffoni, S, Leontari, I, Martinelli, M, Palumaa, P, Sillard, R, Wang, S, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-07-20 | Release date: | 2007-01-16 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Human Sco1 functional studies and pathological implications of the P174L mutant. Proc.Natl.Acad.Sci.Usa, 104, 2007
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