2HRF

Solution Structure of Cu(I) P174L HSco1

Summary for 2HRF

Entry DOI	10.2210/pdb2hrf/pdb
Related	2GQK 2GQL 2GQM 2GT5 2GT6 2GVP 2HRN
Descriptor	SCO1 protein homolog, mitochondrial, COPPER (I) ION (2 entities in total)
Functional Keywords	chaperone, mitochondrion, metal-binding, disease mutation, structural genomics, structural proteomics in europe, spine, metal transport
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion: O75880
Total number of polymer chains	1
Total formula weight	19791.87
Authors	Banci, L.,Bertini, I.,Ciofi-Baffoni, S.,Leontari, I.,Martinelli, M.,Palumaa, P.,Sillard, R.,Wang, S.,Structural Proteomics in Europe (SPINE) (deposition date: 2006-07-20, release date: 2007-01-16, Last modification date: 2021-10-20)
Primary citation	Banci, L.,Bertini, I.,Ciofi-Baffoni, S.,Leontari, I.,Martinelli, M.,Palumaa, P.,Sillard, R.,Wang, S. Human Sco1 functional studies and pathological implications of the P174L mutant. Proc.Natl.Acad.Sci.Usa, 104:15-20, 2007 Cited by PubMed: 17182746 DOI: 10.1073/pnas.0606189103 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation