PDB: 243083 resultsInfo pagesStatus searchChemie searchBIRD

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4FJP	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Naproxen at 1.68 A Resolution Descriptor: (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Shukla, P.K, Gautam, L, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2012-06-12 Release date: 2012-06-27 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Naproxen at 1.68 A Resolution To be Published
1UC0	Crystal structure of wild-type hen-egg white lysozyme singly labeled with 2',3'-epoxypropyl beta-glycoside of N-acetyllactosamine Descriptor: GLYCEROL, Lysozyme C, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Muraki, M, Harata, K. Deposit date: 2003-04-07 Release date: 2003-04-22 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: X-ray structural analysis of the ligand-recognition mechanism in the dual-affinity labeling of c-type lysozyme with 2',3'-epoxypropyl beta-glycoside of N-acetyllactosamine J.MOL.RECOG., 16, 2003
5RF7	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z316425948_minor Descriptor: 1-(4-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one, 3C-like proteinase, DIMETHYL SULFOXIDE Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-03-15 Release date: 2020-03-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nat Commun, 11, 2020
5VTZ	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225Q/L226A mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-05-18 Release date: 2017-06-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host Microbe, 21, 2017
5RG0	PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with PCM-0102535 Descriptor: 1,1'-(piperazine-1,4-diyl)di(ethan-1-one), 3C-like proteinase, DIMETHYL SULFOXIDE Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-03-15 Release date: 2020-03-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nat Commun, 11, 2020
5RGL	PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with PCM-0102962 (Mpro-x0705) Descriptor: 1-[4-(4-methylbenzene-1-carbonyl)piperazin-1-yl]ethan-1-one, 3C-like proteinase, DIMETHYL SULFOXIDE Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-04-07 Release date: 2020-04-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nat Commun, 11, 2020
1TVP	Endoglucanase cel5G from Pseudoalteromonas haloplanktis in complex with cellobiose Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, cellulase Authors: Violot, S, Haser, R, Aghajari, N. Deposit date: 2004-06-30 Release date: 2005-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of a Full Length Psychrophilic Cellulase from Pseudoalteromonas haloplanktis revealed by X-ray Diffraction and Small Angle X-ray Scattering J.Mol.Biol., 348, 2005
4JXE	Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMSH-like protease sst2, ... Authors: Shrestha, R.K, Das, C. Deposit date: 2013-03-28 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.451 Å) Cite: Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
4BQI	ARABIDOPSIS THALIANA cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with maltotriose Descriptor: ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC, DI(HYDROXYETHYL)ETHER, ... Authors: O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A. Deposit date: 2013-05-30 Release date: 2014-02-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials Chem.Sci., 5, 2014
2A15	X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution Descriptor: HYPOTHETICAL PROTEIN Rv0760c, NICOTINAMIDE Authors: Garen, C.R, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC) Deposit date: 2005-06-17 Release date: 2005-10-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase Biochim.Biophys.Acta, 1784, 2008
2JV9	The Solution Structure of Calponin Homology Domain from Smoothelin-like 1 Descriptor: Smoothelin-like 1 Authors: Ishida, H, Vogel, H.J, MacDonald, J.A. Deposit date: 2007-09-12 Release date: 2008-05-27 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution Structure of the Calponin Homology (CH) Domain from the Smoothelin-like 1 Protein: A UNIQUE APOCALMODULIN-BINDING MODE AND THE POSSIBLE ROLE OF THE C-TERMINAL TYPE-2 CH-DOMAIN IN SMOOTH MUSCLE RELAXATION. J.Biol.Chem., 283, 2008
3EOA	Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I Descriptor: Efalizumab Fab fragment, heavy chain, light chain, ... Authors: Li, S, Ding, J. Deposit date: 2008-09-26 Release date: 2009-04-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc.Natl.Acad.Sci.USA, 106, 2009
4BUL	Novel hydroxyl tricyclics (e.g. GSK966587) as potent inhibitors of bacterial type IIA topoisomerases Descriptor: (S)-4-((4-(((2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methyl)amino)piperidin-1-yl)methyl)-3-fluoro-4-hydroxy-4H-pyrrolo[3,2,1-de][1,5]naphthyridin-7(5H)-one, 5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*AP*CP *CP*GP*CP*AP*C)-3', 5'-D(*TP*GP*TP*GP*CP*GP*GP*TP*GP*TP*AP*CP*CP*TP *AP*CP*GP*GP*CP*T)-3', ... Authors: Miles, T.J, Hennessy, A.J, Bax, B, Brooks, G, Brown, B.S, Brown, P, Cailleau, N, Chen, D, Dabbs, S, Davies, D.T, Esken, J.M, Giordano, I, Hoover, J.L, Huang, J, Jones, G.E, Sukmar, S.K.K, Spitzfaden, C, Markwell, R.E, Minthorn, E.A, Rittenhouse, S, Gwynn, M.N, Pearson, N.D. Deposit date: 2013-06-20 Release date: 2013-08-07 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Novel Hydroxyl Tricyclics (E.G., Gsk966587) as Potent Inhibitors of Bacterial Type Iia Topoisomerases. Bioorg.Med.Chem.Lett., 23, 2013
1A5V	ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3 AND MN CATION Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE, MANGANESE (II) ION Authors: Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A. Deposit date: 1998-02-18 Release date: 1998-05-27 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor. Proc.Natl.Acad.Sci.USA, 95, 1998
257L	AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME) Authors: Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W. Deposit date: 1999-01-05 Release date: 2000-09-11 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site. Protein Eng., 13, 2000
2Z6D	Crystal structure of LOV1 domain of phototropin2 from Arabidopsis thaliana Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2 Authors: Nakasako, M, Matsuoka, D, Tokutomi, S. Deposit date: 2007-07-29 Release date: 2008-07-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis of the LOV1 dimerization of Arabidopsis phototropins 1 and 2 J.Mol.Biol., 381, 2008
2OSS	Crystal structure of the Bromo domain 1 in human Bromodomain Containing Protein 4 (BRD4) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4 Authors: Filippakopoulos, P, Keates, T, Savitsky, P, Burgess, N, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2007-02-06 Release date: 2007-02-20 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3QGJ	1.3A Structure of alpha-Lytic Protease Bound to Ac-AlaAlaPro-Alanal Descriptor: 1,2-ETHANEDIOL, Ac-AlaAlaPro-Alanal peptide, Alpha-lytic protease, ... Authors: Everill, P, Meinke, G, Bohm, A, Bachovchin, W. Deposit date: 2011-01-24 Release date: 2012-02-01 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Substrate Binding Defines Ser195 Position in the Catalytic Triad of Serine Proteases, Not His57 protonation To be Published
2GOL	Xray Structure of Gag278 Descriptor: Capsid protein p24 (CA), Matrix protein p17 (MA), SULFATE ION Authors: Kelly, B.N. Deposit date: 2006-04-13 Release date: 2006-09-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1-278 and CAN 133-278. Biochemistry, 45, 2006
3BOV	Crystal structure of the receptor binding domain of mouse PD-L2 Descriptor: FORMIC ACID, Programmed cell death 1 ligand 2, SODIUM ION Authors: Lazar-Molnar, E, Ramagopal, U, Cao, E, Toro, R, Nathenson, S.G, Almo, S.C. Deposit date: 2007-12-17 Release date: 2008-07-15 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc.Natl.Acad.Sci.USA, 105, 2008
4CA5	Human Angiotensin converting enzyme in complex with a phosphinic tripeptide FI Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... Authors: Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. Deposit date: 2013-10-07 Release date: 2013-12-11 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
1QW8	Crystal structure of a family 51 alpha-L-arabinofuranosidase in complex with Ara-alpha(1,3)-Xyl Descriptor: Alpha-L-arabinofuranosidase, alpha-L-arabinofuranose-(1-3)-beta-D-xylopyranose Authors: Hoevel, K, Shallom, D, Niefind, K, Belakhov, V, Shoham, G, Bassov, T, Shoham, Y, Schomburg, D. Deposit date: 2003-09-01 Release date: 2003-10-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure and snapshots along the reaction pathway of a family 51 alpha-L-arabinofuranosidase Embo J., 22, 2003
3U7U	Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuregulin 1, Receptor tyrosine-protein kinase erbB-4 Authors: Liu, P, Cleveland IV, T.E, Bouyain, S, Longo, P.A, Leahy, D.J. Deposit date: 2011-10-14 Release date: 2012-08-29 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3.03 Å) Cite: A single ligand is sufficient to activate EGFR dimers. Proc.Natl.Acad.Sci.USA, 109, 2012
5VTV	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant in complex with 3'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-05-18 Release date: 2017-06-28 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host Microbe, 21, 2017
1UU9	Structure of human PDK1 kinase domain in complex with BIM-3 Descriptor: 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, GLYCEROL, ... Authors: Komander, D, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Garrido-Franco, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. Deposit date: 2003-12-16 Release date: 2004-03-04 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12, 2004

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