4DQU
| Mycobacterium tuberculosis InhA-D148G mutant in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Pojer, F, Hartkoorn, R.C, Boy, S, Cole, S.T. | Deposit date: | 2012-02-16 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4, 2012
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4C7A
| Crystal structure of the Smoothened CRD, selenomethionine-labeled | Descriptor: | SMOOTHENED, SODIUM ION, ZINC ION | Authors: | Nachtergaele, S, Whalen, D.M, Mydock, L.K, Zhao, Z, Malinauskas, T, Krishnan, K, Ingham, P.W, Covey, D.F, Rohatgi, R, Siebold, C. | Deposit date: | 2013-09-20 | Release date: | 2013-11-06 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Function of the Smoothened Extracellular Domain in Vertebrate Hedgehog Signaling Elife, 2, 2013
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4BXQ
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4D2Q
| Negative-stain electron microscopy of E. coli ClpB mutant E432A (BAP form bound to ClpP) | Descriptor: | CLPB | Authors: | Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R. | Deposit date: | 2014-05-12 | Release date: | 2014-06-04 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (18 Å) | Cite: | Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation. Elife, 3, 2014
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4D2X
| Negative-stain electron microscopy of E. coli ClpB of Y503D hyperactive mutant (BAP form bound to ClpP) | Descriptor: | CHAPERONE PROTEIN CLPB | Authors: | Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R. | Deposit date: | 2014-05-13 | Release date: | 2014-06-04 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation. Elife, 3, 2014
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4B08
| Yeast DNA polymerase alpha, Selenomethionine protein | Descriptor: | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A | Authors: | Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. | Deposit date: | 2012-06-29 | Release date: | 2013-02-27 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha Elife, 2, 2013
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4BL0
| Crystal structure of yeast Bub3-Bub1 bound to phospho-Spc105 | Descriptor: | CELL CYCLE ARREST PROTEIN BUB3, CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, MAGNESIUM ION, ... | Authors: | Primorac, I, Weir, J.R, Musacchio, A. | Deposit date: | 2013-04-30 | Release date: | 2013-09-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Bub3 Reads Phosphorylated Melt Repeats to Promote Spindle Assembly Checkpoint Signaling Elife, 2, 2013
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4BZI
| The structure of the COPII coat assembled on membranes | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SAR1P, ... | Authors: | Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G. | Deposit date: | 2013-07-26 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes Elife, 2, 2013
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4CI0
| Electron cryo-microscopy of F420-reducing NiFe hydrogenase Frh | Descriptor: | F420-REDUCING HYDROGENASE, SUBUNIT ALPHA, SUBUNIT BETA, ... | Authors: | Allegretti, M, Mills, D.J, McMullan, G, Kuehlbrandt, W, Vonck, J. | Deposit date: | 2013-12-05 | Release date: | 2014-02-26 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Atomic Model of the F420-Reducing [Nife] Hydrogenase by Electron Cryo-Electron Microscopy Using a Direct Electron Detector. Elife, 3, 2014
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4D2U
| Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP) | Descriptor: | CHAPERONE PROTEIN CLPB | Authors: | Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R. | Deposit date: | 2014-05-13 | Release date: | 2014-06-04 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation. Elife, 3, 2014
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4BNQ
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4CS8
| Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 2 | Descriptor: | M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4CKM
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4CS7
| Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 1 | Descriptor: | M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4CS9
| Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to adenosine monophosphate | Descriptor: | ADENOSINE MONOPHOSPHATE, M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4BXP
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4BZJ
| The structure of the COPII coat assembled on membranes | Descriptor: | Protein transport protein SEC13, Protein transport protein SEC31 | Authors: | Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G. | Deposit date: | 2013-07-26 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (40 Å) | Cite: | The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes Elife, 2, 2013
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4CZE
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4CZJ
| C. crescentus MreB, double filament, AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ROD SHAPE-DETERMINING PROTEIN MREB | Authors: | Lowe, J, van den Ent, F. | Deposit date: | 2014-04-19 | Release date: | 2014-06-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments. Elife, 3, 2014
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4CZF
| C. crescentus MreB, single filament, ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ROD SHAPE-DETERMINING PROTEIN MREB | Authors: | Lowe, J, vandenEnt, F. | Deposit date: | 2014-04-19 | Release date: | 2014-06-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments. Elife, 3, 2014
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4BZK
| The structure of the COPII coat assembled on membranes | Descriptor: | Protein transport protein SEC13, Protein transport protein SEC31 | Authors: | Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G. | Deposit date: | 2013-07-26 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (40 Å) | Cite: | The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes Elife, 2, 2013
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4DTI
| Mycobacterium tuberculosis InhA-S94A mutant in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Pojer, F, Hartkoorn, R.C, Boy, S, Cole, S.T. | Deposit date: | 2012-02-21 | Release date: | 2012-10-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4, 2012
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4DRE
| Mycobacterium tuberculosis InhA in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Pojer, F, Hartkoorn, R.C, Boy, S, Cole, S.T. | Deposit date: | 2012-02-17 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4, 2012
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4C3P
| Structure of dephosphorylated Aurora A (122-403) bound to TPX2 and AMPPCP | Descriptor: | AURORA KINASE A, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION, ... | Authors: | Zorba, A, Kutter, S, Kern, D. | Deposit date: | 2013-08-26 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Molecular Mechanism of Aurora a Kinase Autophosphorylation and its Allosteric Activation by Tpx2. Elife, 3, 2014
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4BXR
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