4DTI

Mycobacterium tuberculosis InhA-S94A mutant in complex with NADH

Summary for 4DTI

• Entry DOI: 10.2210/pdb4dti/pdb
• Related: 4DQU 4DRE
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE (3 entities in total)
• Functional Keywords: enoyl-acp reductase, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 29204.22

Authors

Pojer, F.,Hartkoorn, R.C.,Boy, S.,Cole, S.T. (deposition date: 2012-02-21, release date: 2012-10-03, Last modification date: 2023-09-13)

• Primary citation: Hartkoorn, R.C.,Sala, C.,Neres, J.,Pojer, F.,Magnet, S.,Mukherjee, R.,Uplekar, S.,Boy-Rottger, S.,Altmann, K.H.,Cole, S.T.; Towards a new tuberculosis drug: pyridomycin - nature's isoniazid.; EMBO Mol Med, 4:1032-1042, 2012; PubMed: 22987724; DOI: 10.1002/emmm.201201689

Experimental method

X-RAY DIFFRACTION (1.9 Å)