4C7A

Crystal structure of the Smoothened CRD, selenomethionine-labeled

Summary for 4C7A

• Entry DOI: 10.2210/pdb4c7a/pdb
• Related: 4C79
• Descriptor: SMOOTHENED, ZINC ION, SODIUM ION, ... (4 entities in total)
• Functional Keywords: signaling protein
• Biological source: DANIO RERIO (ZEBRAFISH)
• Total number of polymer chains: 2
• Total formula weight: 44797.89

Authors

Nachtergaele, S.,Whalen, D.M.,Mydock, L.K.,Zhao, Z.,Malinauskas, T.,Krishnan, K.,Ingham, P.W.,Covey, D.F.,Rohatgi, R.,Siebold, C. (deposition date: 2013-09-20, release date: 2013-11-06, Last modification date: 2013-11-13)

• Primary citation: Nachtergaele, S.,Whalen, D.M.,Mydock, L.K.,Zhao, Z.,Malinauskas, T.,Krishnan, K.,Ingham, P.W.,Covey, D.F.,Siebold, C.,Rohatgi, R.; Structure and Function of the Smoothened Extracellular Domain in Vertebrate Hedgehog Signaling; Elife, 2:01340-, 2013; PubMed: 24171105; DOI: 10.7554/ELIFE.01340

Experimental method

X-RAY DIFFRACTION (2.3 Å)