4C7A
Crystal structure of the Smoothened CRD, selenomethionine-labeled
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SMOOTHENED | polymer | 193 | 22331.8 | 2 | UniProt (Q90X26) Pfam (PF01392) UniProt (by SIFTS) (Q5RH73) | DANIO RERIO (ZEBRAFISH) | |
| 2 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | D, E, F (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 210 (UniProt: Q90X26)
| PDB | External Database | Details |
|---|---|---|
| Mse 27 | - | expression tag |
| Lys 211 | - | expression tag |
| Leu 212 | - | expression tag |
| Glu 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44663.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 134.4 | |
| All* | Total formula weight | 44797.9 |
