4DQU
Mycobacterium tuberculosis InhA-D148G mutant in complex with NADH
Summary for 4DQU
Entry DOI | 10.2210/pdb4dqu/pdb |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | enoyl-acp reductase, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 29162.18 |
Authors | Pojer, F.,Hartkoorn, R.C.,Boy, S.,Cole, S.T. (deposition date: 2012-02-16, release date: 2012-10-03, Last modification date: 2024-02-28) |
Primary citation | Hartkoorn, R.C.,Sala, C.,Neres, J.,Pojer, F.,Magnet, S.,Mukherjee, R.,Uplekar, S.,Boy-Rottger, S.,Altmann, K.H.,Cole, S.T. Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4:1032-1042, 2012 Cited by PubMed: 22987724DOI: 10.1002/emmm.201201689 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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