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3PVB
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BU of 3pvb by Molmil
Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S.
Deposit date:2010-12-06
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Structure, 19, 2011
7XUF
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BU of 7xuf by Molmil
Cryo-EM structure of the AKT1-AtKC1 complex from Arabidopsis thaliana
Descriptor: POTASSIUM ION, Potassium channel AKT1, Potassium channel KAT3
Authors:Yang, G.H, Lu, Y.M, Jia, Y.T, Yang, F, Zhang, Y.M, Xu, X, Li, X.M, Lei, J.L.
Deposit date:2022-05-18
Release date:2022-11-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
7NP4
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BU of 7np4 by Molmil
cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A.
Deposit date:2021-02-26
Release date:2021-08-11
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
7NP3
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BU of 7np3 by Molmil
cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Giese, H.M, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A.
Deposit date:2021-02-26
Release date:2021-08-11
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
7RHH
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BU of 7rhh by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openI state
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7RHI
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BU of 7rhi by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openII state
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-17
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
8EV9
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BU of 8ev9 by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVC
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BU of 8evc by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, open state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVA
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BU of 8eva by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8XQ8
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BU of 8xq8 by Molmil
Structure of the sea urchin spSLC9C1 in state-1 w/ cAMP protomer
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger
Authors:Qu, H, Zheng, X.
Deposit date:2024-01-04
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structures of a sperm-specific sodium-hydrogen exchanger.
Cell Insight, 3, 2024
6CJU
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BU of 6cju by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
8PD7
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BU of 8pd7 by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 4
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PD5
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BU of 8pd5 by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 3
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
7O4H
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BU of 7o4h by Molmil
The structure of the native CNGA1/CNGB1 CNG channel from retinal rods
Descriptor: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Barret, D.C.A, Marino, J.
Deposit date:2021-04-06
Release date:2022-01-12
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The structure of the native CNGA1/CNGB1 CNG channel from bovine retinal rods.
Nat.Struct.Mol.Biol., 29, 2022
7WSW
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BU of 7wsw by Molmil
Cryo-EM structure of the Potassium channel AKT1 from Arabidopsis thaliana
Descriptor: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
Authors:Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
Deposit date:2022-02-02
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
6GYO
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BU of 6gyo by Molmil
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-06-30
Release date:2019-05-01
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
6GYN
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BU of 6gyn by Molmil
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-06-30
Release date:2019-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
7YIE
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BU of 7yie by Molmil
Human KCNH5-closed state 2
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YID
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BU of 7yid by Molmil
Human KCNH5 closed state 1
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
Authors:Zhang, M.F.
Deposit date:2022-07-16
Release date:2023-04-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
8J2M
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BU of 8j2m by Molmil
The truncated rice Na+/H+ antiporter SOS1 (1-976) in a constitutively active state
Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Na+/H+ antiporter
Authors:Zhang, X.Y, Tang, L.H, Zhang, C.R, Nie, J.W.
Deposit date:2023-04-14
Release date:2023-11-22
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and activation mechanism of the rice Salt Overly Sensitive 1 (SOS1) Na + /H + antiporter.
Nat.Plants, 9, 2023
8WUI
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BU of 8wui by Molmil
SKOR D312N L271P double mutation
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR
Authors:Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G.
Deposit date:2023-10-20
Release date:2024-04-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel.
Plant Commun., 5, 2024
6VXZ
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BU of 6vxz by Molmil
SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
Authors:Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
Deposit date:2020-02-25
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
6CJQ
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BU of 6cjq by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6CJT
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BU of 6cjt by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cGMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CYCLIC GUANOSINE MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
5H3O
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BU of 5h3o by Molmil
Structure of a eukaryotic cyclic nucleotide-gated channel
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION
Authors:Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J.
Deposit date:2016-10-26
Release date:2017-01-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of a eukaryotic cyclic-nucleotide-gated channel.
Nature, 542, 2017

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