PDB: 3581 resultsInfo pagesStatus searchChemie searchBIRD

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6F0B	Cytochrome P450 TxtC employs substrate conformational switching for sequential aliphatic and aromatic thaxtomin hydroxylation Descriptor: (3~{S},6~{S})-1,4-dimethyl-3-[(4-nitro-1~{H}-indol-3-yl)methyl]-6-(phenylmethyl)piperazine-2,5-dione, Cytochrome P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE Authors: Fulop, V. Deposit date: 2017-11-17 Release date: 2018-12-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC. J.Am.Chem.Soc., 141, 2019
6F8C	Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with progesterone Descriptor: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE Authors: Jozwik, I.K, Thunnissen, A.M.W.H. Deposit date: 2017-12-12 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
2BVJ	Ligand-free structure of cytochrome P450 PikC (CYP107L1) Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CYTOCHROME P450 MONOOXYGENASE, ... Authors: Sherman, D.H, Li, S, Yermalitskaya, L.V, Kim, Y, Smith, J.A, Waterman, M.R, Podust, L.M. Deposit date: 2005-06-28 Release date: 2006-07-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281, 2006
6F85	Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with histidine Descriptor: Cytochrome P450 CYP260A1, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE Authors: Jozwik, I.K, Thunnissen, A.M.W.H. Deposit date: 2017-12-12 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
6F8A	Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with histidine Descriptor: Cytochrome P450 CYP260A1, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE Authors: Jozwik, I.K, Thunnissen, A.M.W.H. Deposit date: 2017-12-12 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
6G5Q	The structure of a carbohydrate active P450 Descriptor: 6-O-methyl-beta-D-galactopyranose, Cytochrome P450, GLYCEROL, ... Authors: Robb, C.S, Hehemann, J.H. Deposit date: 2018-03-29 Release date: 2018-11-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases. Biochem. J., 475, 2018
6FSH	Crystal structure of hybrid P450 OxyBtei(BC/FGvan) Descriptor: ACETATE ION, OxyB protein, POTASSIUM ION, ... Authors: Brieke, C, Tarnawski, M, Greule, A, Cryle, M.J. Deposit date: 2018-02-19 Release date: 2018-05-23 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach. J. Inorg. Biochem., 185, 2018
2CP4	CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA Descriptor: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Raag, R, Poulos, T.L. Deposit date: 1991-06-04 Release date: 1993-01-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. Biochemistry, 30, 1991
6EIG	Crystal structure of N24Q/C128T mutant of Channelrhodopsin 2 Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, EICOSANE, ... Authors: Kovalev, K, Borshchevskiy, V, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. Deposit date: 2017-09-19 Release date: 2017-12-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
6FSA	Beta-Cardiac myosin post-rigor Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ... Authors: Robert-Paganin, J, Auguin, D, Houdusse, A. Deposit date: 2018-02-19 Release date: 2018-07-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition. Nat Commun, 9, 2018
6FYJ	Cytochrome P450 peroxygenase CYP152K6 in complex with Myristic Acid Descriptor: DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, MYRISTIC ACID, ... Authors: Girvan, H.M, Poddar, H, Mclean, K.J, Leys, D, Munro, A.W. Deposit date: 2018-03-12 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus. J. Inorg. Biochem., 188, 2018
6G5O	The structure of a carbohydrate active P450 Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE Authors: Robb, C.S, Hehemann, J.H. Deposit date: 2018-03-29 Release date: 2018-11-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases. Biochem. J., 475, 2018
6GK5	Crystal structure of cytochrome P450 CYP267B1 from Sorangium cellulosum So ce56 Descriptor: Cytochrome P450 CYP267B1 protein, PROTOPORPHYRIN IX CONTAINING FE Authors: Jozwik, I.K, Thunnissen, A.M.W.H. Deposit date: 2018-05-18 Release date: 2018-08-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1. Biochem. J., 475, 2018
6G71	Structure of CYP1232A24 from Arthrobacter sp. Descriptor: 1,2-ETHANEDIOL, Cytochrome P450, FE (III) ION, ... Authors: Dubiel, P, Sharma, M, Klenk, J, Hauer, B, Grogan, G. Deposit date: 2018-04-04 Release date: 2019-03-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine. J.Biochem., 166, 2019
6GEO	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 10j Descriptor: 2-chloranyl-3-[4-(imidazol-1-ylmethyl)-1-phenyl-pyrazol-3-yl]-1~{H}-indole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Levy, C.W. Deposit date: 2018-04-27 Release date: 2019-08-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
6GEQ	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 14a Descriptor: 1-phenyl-3-pyridin-4-yl-~{N}-(pyridin-4-ylmethyl)pyrazole-4-carboxamide, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Levy, C.W. Deposit date: 2018-04-27 Release date: 2019-08-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
6FVC	Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants Descriptor: Segmentation polarity homeobox protein engrailed Authors: Trosanova, Z, Zachrdla, M, Jansen, S, Srb, P, Zidek, L, Kozelka, J. Deposit date: 2018-03-02 Release date: 2019-04-03 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants. Phys Chem Chem Phys, 20, 2018
2CPP	HIGH-RESOLUTION CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM Descriptor: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1987-04-06 Release date: 1987-07-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.63 Å) Cite: High-resolution crystal structure of cytochrome P450cam. J.Mol.Biol., 195, 1987
2FER	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX Descriptor: Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN Authors: von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. Deposit date: 2005-12-16 Release date: 2006-03-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FEU	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... Authors: von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. Deposit date: 2005-12-16 Release date: 2006-03-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FE6	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX Descriptor: Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN Authors: von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. Deposit date: 2005-12-15 Release date: 2006-03-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FR7	Crystal Structure of Cytochrome P450 CYP199A2 Descriptor: PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450 Authors: Rao, Z, Wong, L.L, Xu, F, Bell, S.G. Deposit date: 2006-01-19 Release date: 2007-01-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris J.Mol.Biol., 383, 2008
4CQI	Crystal structure of recombinant tubulin-binding cofactor A (TBCA) from Leishmania major Descriptor: GLYCEROL, SULFATE ION, TUBULIN-BINDING COFACTOR A Authors: Barrack, K.L, Fyfe, P.K, Hunter, W.N. Deposit date: 2014-02-17 Release date: 2014-11-26 Last modified: 2015-05-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Structure of Tubulin-Binding Cofactor a from Leishmania Major Infers a Mode of Association During the Early Stages of Microtubule Assembly Acta Crystallogr.,Sect.F, 71, 2015
4CP4	CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA Descriptor: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Raag, R, Poulos, T.L. Deposit date: 1991-06-04 Release date: 1993-01-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. Biochemistry, 30, 1991
7JW5	Crystal structure of WT-CYP199A4 in complex with 4-phenylbenzoic acid Descriptor: CHLORIDE ION, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Lee, J.H.Z, Bruning, J.B, Bell, S.G. Deposit date: 2020-08-24 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.526 Å) Cite: Different Geometric Requirements for Cytochrome P450-Catalyzed Aliphatic Versus Aromatic Hydroxylation Results in Chemoselective Oxidation Acs Catalysis, 12, 2022

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