1W4Y
| Ferrous horseradish peroxidase C1A in complex with carbon monoxide | Descriptor: | CALCIUM ION, CARBON MONOXIDE, HORSERADISH PEROXIDASE C1A, ... | Authors: | Carlsson, G.H, Nicholls, P, Svistunenko, D, Berglund, G.I, Hajdu, J. | Deposit date: | 2004-08-03 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Complexes of Horseradish Peroxidase with Formate, Acetate, and Carbon Monoxide Biochemistry, 44, 2005
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6FRR
| Structural and immunological properties of the allergen Art v 3 | Descriptor: | Non-specific lipid-transfer protein, SULFATE ION | Authors: | Brandstetter, H, Soh, W.T, Magler, I. | Deposit date: | 2018-02-16 | Release date: | 2019-03-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Boiling down the cysteine-stabilized LTP fold - loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation. Mol.Immunol., 116, 2019
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1W4W
| Ferric horseradish peroxidase C1A in complex with formate | Descriptor: | CALCIUM ION, FORMIC ACID, HORSERADISH PEROXIDASE C1A, ... | Authors: | Carlsson, G.H, Nicholls, P, Svistunenko, D, Berglund, G.I, Hajdu, J. | Deposit date: | 2004-08-03 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Complexes of Horseradish Peroxidase with Formate, Acetate, and Carbon Monoxide Biochemistry, 44, 2005
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1GAB
| STRUCTURE OF AN ALBUMIN-BINDING DOMAIN, NMR, 20 STRUCTURES | Descriptor: | PROTEIN PAB | Authors: | Johansson, M.U, De Chateau, M, Wikstrom, M, Forsen, S, Drakenberg, T, Bjorck, L. | Deposit date: | 1996-12-30 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the albumin-binding GA module: a versatile bacterial protein domain. J.Mol.Biol., 266, 1997
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8V6K
| Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8V6N
| Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, ARACHIDONIC ACID, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8UTK
| IL-23R minibinder - 23R-B04dslf02IB | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 23R-B04dslf02IB, ... | Authors: | Bera, A.K, Berger, S.A, Kang, A, Baker, D. | Deposit date: | 2023-10-31 | Release date: | 2024-07-10 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell, 187, 2024
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7NPD
| Vibiro cholerae ParA2 | Descriptor: | Walker A-type ATPase | Authors: | Parker, A.V, Bergeron, J.R.C. | Deposit date: | 2021-02-26 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding. Nat Commun, 12, 2021
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7AON
| Crystal structure of CI2 double mutant L49I,I57V | Descriptor: | GLYCEROL, SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A | Authors: | Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V. | Deposit date: | 2020-10-14 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Commun Biol, 4, 2021
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7AOK
| Crystal structure of CI2 mutant L49I | Descriptor: | SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A | Authors: | Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V. | Deposit date: | 2020-10-14 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Commun Biol, 4, 2021
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8V6O
| Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, SODIUM ION, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8V6L
| Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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8V6M
| Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Tetrahydrocannabivarin, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2023-12-01 | Release date: | 2024-04-17 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. Sci Adv, 10, 2024
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1I4A
| CRYSTAL STRUCTURE OF PHOSPHORYLATION-MIMICKING MUTANT T6D OF ANNEXIN IV | Descriptor: | ANNEXIN IV, CALCIUM ION, SULFATE ION | Authors: | Kaetzel, M.A, Mo, Y.D, Mealy, T.R, Campos, B, Bergsma-Schutter, W, Brisson, A, Dedman, J.R, Seaton, B.A. | Deposit date: | 2001-02-20 | Release date: | 2001-04-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation. Biochemistry, 40, 2001
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1E4X
| crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment | Descriptor: | CYCLIC PEPTIDE, TAB2 | Authors: | Hahn, M, Winkler, D, Misselwitz, R, Wessner, H, Welfle, K, Zahn, G, Schneider-Mergener, J, Hoehne, W. | Deposit date: | 2000-07-12 | Release date: | 2001-07-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cross-Reactive Binding of Cyclic Peptides to an Anti-Tgf Alpha Antibody Fab Fragment: An X-Ray Structural and Thermodynamic Analysis J.Mol.Biol., 314, 2001
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1EC0
| HIV-1 protease in complex with the inhibitor bea403 | Descriptor: | HIV-1 PROTEASE, N,N-[2,5-O-DI-2-FLUORO-BENZYL-GLUCARYL]-DI-[1-AMINO-INDAN-2-OL] | Authors: | Unge, T. | Deposit date: | 2000-01-25 | Release date: | 2002-06-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy Eur.J.Biochem., 271, 2004
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6AMC
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6YQ7
| Taka-amylase | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... | Authors: | Armstrong, Z, Chen, Y, Artola, M, Overkleeft, H, Davies, G. | Deposit date: | 2020-04-16 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Activity-Based Protein Profiling of Retaining alpha-Amylases in Complex Biological Samples. J.Am.Chem.Soc., 143, 2021
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6YQC
| Taka-amylase in complex with alpha-glucosyl epi-cyclophellitol epoxide inhibitor | Descriptor: | (1~{R},2~{S},4~{R},5~{S},6~{R})-6-[(2~{S},3~{R},4~{R},5~{S},6~{R})-5-heptoxy-6-(hydroxymethyl)-3,4-bis(oxidanyl)oxan-2-yl]oxy-5-(hydroxymethyl)cyclohexane-1,2,4-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Armstrong, Z, Chen, Y, Artola, M, Overkleeft, H, Davies, G. | Deposit date: | 2020-04-16 | Release date: | 2021-02-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Activity-Based Protein Profiling of Retaining alpha-Amylases in Complex Biological Samples. J.Am.Chem.Soc., 143, 2021
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6YQ9
| Taka-amylase in complex with alpha-glucosyl epi-cyclophellitol epoxide inhibitor | Descriptor: | (1R,2R,3S,5R,6S)-2,3,5-trihydroxy-6-(hydroxymethyl)cyclohexyl alpha-D-glucopyranoside, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Armstrong, Z, Chen, Y, Artola, M, Overkleeft, H, Davies, G. | Deposit date: | 2020-04-16 | Release date: | 2021-02-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Activity-Based Protein Profiling of Retaining alpha-Amylases in Complex Biological Samples. J.Am.Chem.Soc., 143, 2021
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6YQB
| Taka-amylase in complex with alpha-glucosyl epi-cyclophellitol cyclosulfate inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... | Authors: | Armstrong, Z, Chen, Y, Artola, M, Overkleeft, H, Davies, G. | Deposit date: | 2020-04-16 | Release date: | 2021-02-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Activity-Based Protein Profiling of Retaining alpha-Amylases in Complex Biological Samples. J.Am.Chem.Soc., 143, 2021
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1EEH
| UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE | Descriptor: | UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE, URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE | Authors: | Bertrand, J.A, Fanchon, E, Martin, L, Chantalat, L, Auger, G, Blanot, D, van Heijenoort, J, Dideberg, O. | Deposit date: | 2000-01-31 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | "Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase. J.Mol.Biol., 301, 2000
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6YQA
| Taka-amylase in complex with alpha-glucosyl epi-cyclophellitol aziridine inhibitor | Descriptor: | (1~{S},2~{R},3~{R},4~{R},5~{R})-5-(8-azanyloctylamino)-4-(hydroxymethyl)cyclohexane-1,2,3-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Armstrong, Z, Chen, Y, Artola, M, Overkleeft, H, Davies, G. | Deposit date: | 2020-04-16 | Release date: | 2021-02-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Activity-Based Protein Profiling of Retaining alpha-Amylases in Complex Biological Samples. J.Am.Chem.Soc., 143, 2021
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6R5H
| Major aspartyl peptidase 1 from C. neoformans | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | Authors: | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | Deposit date: | 2019-03-25 | Release date: | 2021-04-07 | Last modified: | 2021-06-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. J.Med.Chem., 64, 2021
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6R6A
| Major aspartyl peptidase 1 from C. neoformans | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Endopeptidase, ... | Authors: | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | Deposit date: | 2019-03-26 | Release date: | 2021-04-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. J.Med.Chem., 64, 2021
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