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2DQJ
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BU of 2dqj by Molmil
Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution
Descriptor: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
Authors:Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I.
Deposit date:2006-05-26
Release date:2007-01-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL
J.Biol.Chem., 282, 2007
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Descriptor: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
Authors:Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-07-01
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
6IW5
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BU of 6iw5 by Molmil
Crystal structure of YFV-China sE in prefusion state
Descriptor: Envelope protein
Authors:Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F.
Deposit date:2018-12-04
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
6PZW
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BU of 6pzw by Molmil
CryoEM derived model of NA-22 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-22 fragment antigen binding heavy chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-01
Release date:2019-12-04
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZD
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BU of 6pzd by Molmil
Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2019-07-31
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZE
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BU of 6pze by Molmil
Crystal structure of human NA-45 Fab in complex with neuraminidase Y169aH mutant from A/Shanghai/2/2013 (H7N9)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NA-45 FAB HEAVY CHAIN, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2019-07-31
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZF
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BU of 6pzf by Molmil
Crystal structure of human NA-63 Fab in complex with neuraminidase from A/Hunan/02650/2016(H7N9)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2019-07-31
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Z06
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BU of 6z06 by Molmil
Crystal structure of Puumala virus Gc in complex with Fab 4G2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ...
Authors:Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A.
Deposit date:2020-05-07
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
6W73
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BU of 6w73 by Molmil
Fab Structure of CD4 Binding Site (CD4bs) Huamn Monoclonal Antibody HmAb64
Descriptor: CALCIUM ION, HmAb64 fab heavy chain, HmAb64 fab light chain
Authors:Kong, X, Pan, R.
Deposit date:2020-03-18
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A CD4 Binding Site (CD4bs) Monoclonal Antibody Elicited from A Human Volunteer Immunized by a DNA Prime/Protein Boost gp120 HIV Vaccine
To Be Published
2IHL
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BU of 2ihl by Molmil
LYSOZYME (E.C.3.2.1.17) (JAPANESE QUAIL)
Descriptor: JAPANESE QUAIL EGG WHITE LYSOZYME, SODIUM ION
Authors:Houdusse, A, Bentley, G.A, Poljak, R.J, Souchon, H, Zhang, Z.
Deposit date:1993-06-29
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.
Proc.Natl.Acad.Sci.Usa, 90, 1993
5T78
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BU of 5t78 by Molmil
Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, Fab Fragment - AR20.5 - Heavy chain, Fab fragment AR20.5 - Light Chain, ...
Authors:Brooks, C.L, Movahedin, M.
Deposit date:2016-09-02
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
5T6P
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BU of 5t6p by Molmil
Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
Descriptor: Fab Fragment - Heavy Chain, Fab fragment AR20.5 - Light Chain, MUC1 Peptide Fragment
Authors:Brooks, C.L, Movahedin, M.
Deposit date:2016-09-01
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
7B09
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BU of 7b09 by Molmil
Puumala virus glycoprotein (Gc) in complex with fab fragment P-4G2.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ...
Authors:Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A.
Deposit date:2020-11-19
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (13.4 Å)
Cite:Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
5NBW
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BU of 5nbw by Molmil
Crystal structure of the Fab fragment 22F12 in complex with 3-hydroxybenzo[a]pyrene
Descriptor: Fab 22F12 (A,B), Fab 22F12 (L,H), benzo[a]pyren-3-ol
Authors:Skerra, A, Eichinger, A.
Deposit date:2017-03-02
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tight Molecular Recognition of Benzo[a]pyrene by a High-Affinity Antibody.
Angew. Chem. Int. Ed. Engl., 56, 2017
3A67
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BU of 3a67 by Molmil
Crystal Structure of HyHEL-10 Fv mutant LN31D complexed with hen egg white lysozyme
Descriptor: IG VH, anti-lysozyme, Lysozyme C, ...
Authors:Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I.
Deposit date:2009-08-24
Release date:2009-12-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010
3A6C
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BU of 3a6c by Molmil
Crystal Structure of HyHEL-10 Fv mutant LN92D complexed with hen egg white lysozyme
Descriptor: IG VH, anti-lysozyme, Lysozyme C, ...
Authors:Yokota, A, Tsumoto, K, Shiroishi, M, Nakanishi, T, Kondo, H, Kumagai, I.
Deposit date:2009-08-28
Release date:2009-12-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme
J.Biol.Chem., 285, 2010
5CZV
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BU of 5czv by Molmil
Crystal structure of Notch3 NRR in complex with 20350 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 20350 heavy chain, ...
Authors:Hu, T, Fryer, C, Chopra, R, Clark, K.
Deposit date:2015-08-01
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
2XEJ
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BU of 2xej by Molmil
Human glutamate carboxypeptidase II in complex with ARM-M4, urea- based inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Zhang, A.X, Murelli, R, Barinka, C, Michel, J, Cocleaza, A, Jorgensen, W.L, Lubkowski, J, Spiegel, D.A.
Deposit date:2010-05-14
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules.
J.Am.Chem.Soc., 132, 2010
1BVK
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BU of 1bvk by Molmil
HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME
Descriptor: HULYS11, LYSOZYME
Authors:Holmes, M.A, Buss, T.N, Foote, J.
Deposit date:1998-09-16
Release date:1999-02-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational correction mechanisms aiding antigen recognition by a humanized antibody.
J.Exp.Med., 187, 1998
5KOU
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BU of 5kou by Molmil
Crystal structure of the human astrovirus 2 capsid protein spike domain at 1.87-A resolution
Descriptor: Capsid polyprotein VP25
Authors:Bogdanoff, W.A, DuBois, R.M.
Deposit date:2016-07-01
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.867 Å)
Cite:Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization.
J. Virol., 91, 2017
6W05
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BU of 6w05 by Molmil
Crystal structure of Fab356 in complex with NPNA2 peptide from circumsporozoite protein
Descriptor: Fab356 heavy chain, Fab356 light chain, NPNA2 peptide
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2020-02-29
Release date:2020-07-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.516 Å)
Cite:Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6W00
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BU of 6w00 by Molmil
Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein
Descriptor: Fab239 heavy chain, Fab239 light chain, Immunoglobulin G-binding protein G, ...
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2020-02-28
Release date:2020-07-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.853 Å)
Cite:Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WG1
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BU of 6wg1 by Molmil
Crystal structure of Fab399 in complex with NPNA6 peptide from circumsporozoite protein
Descriptor: Fab399 heavy chain, Fab399 light chain, NPNA6 peptide
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2020-04-04
Release date:2020-07-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.086 Å)
Cite:Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6VLK
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BU of 6vlk by Molmil
A varicella-zoster virus glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, ...
Authors:Xing, Y.
Deposit date:2020-01-24
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4529 Å)
Cite:A glycoprotein B-neutralizing antibody structure at 2.8 angstrom uncovers a critical domain for herpesvirus fusion initiation.
Nat Commun, 11, 2020
7B0A
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BU of 7b0a by Molmil
Puumala virus-like particle glycoprotein spike and lattice contacts model.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ...
Authors:Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A.
Deposit date:2020-11-19
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (13.9 Å)
Cite:Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020

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