5T6P
Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
Summary for 5T6P
Entry DOI | 10.2210/pdb5t6p/pdb |
Descriptor | Fab fragment AR20.5 - Light Chain, Fab Fragment - Heavy Chain, MUC1 Peptide Fragment, ... (4 entities in total) |
Functional Keywords | antibody, fab, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 6 |
Total formula weight | 95801.20 |
Authors | Brooks, C.L.,Movahedin, M. (deposition date: 2016-09-01, release date: 2017-01-11, Last modification date: 2023-10-04) |
Primary citation | Movahedin, M.,Brooks, T.M.,Supekar, N.T.,Gokanapudi, N.,Boons, G.J.,Brooks, C.L. Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen. Glycobiology, 27:677-687, 2017 Cited by PubMed: 28025250DOI: 10.1093/glycob/cww131 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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