PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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4TXD	Crystal structure of Thermofilum pendens Csc2 Descriptor: Csc2, ZINC ION Authors: Hrle, A, Conti, E. Deposit date: 2014-07-03 Release date: 2014-08-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.818 Å) Cite: Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. Rna Biol., 11, 2014
4KZZ	Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A Descriptor: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ... Authors: Lomakin, I.B, Steitz, T.A. Deposit date: 2013-05-30 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (7.0305 Å) Cite: The initiation of mammalian protein synthesis and mRNA scanning mechanism. Nature, 500, 2013
1BYX	CHIMERIC HYBRID DUPLEX R(GCAGUGGC).R(GCCA)D(CTGC) COMPRISING THE TRNA-DNA JUNCTION FORMED DURING INITIATION OF HIV-1 REVERSE TRANSCRIPTION Descriptor: DNA/RNA (5'-R(*GP*CP*CP*A)-D(P*CP*TP*GP*C)-3'), RNA (5'-R(*GP*CP*AP*GP*UP*GP*GP*C)-3') Authors: Szyperski, T, Goette, M, Billeter, M, Perola, E, Cellai, L. Deposit date: 1998-10-20 Release date: 1999-10-20 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: NMR structure of the chimeric hybrid duplex r(gcaguggc).r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription. J.Biomol.NMR, 13, 1999
8C8H	Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme Descriptor: Core protein E11, DNA-directed RNA polymerase 133 kDa polypeptide, DNA-directed RNA polymerase 147 kDa polypeptide, ... Authors: Grimm, G, Bartuli, J, Fischer, U. Deposit date: 2023-01-20 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme To Be Published
7B0Y	Structure of a transcribing RNA polymerase II-U1 snRNP complex Descriptor: 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... Authors: Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. Deposit date: 2020-11-23 Release date: 2021-01-13 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure of a transcribing RNA polymerase II-U1 snRNP complex. Science, 371, 2021
6WDR	Subunit joining exposes nascent pre-40S rRNA for processing and quality control Descriptor: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S10-A, ... Authors: Rai, J, Parker, M.D, Huang, H, Choy, S, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E. Deposit date: 2020-04-01 Release date: 2020-09-30 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7. Rna, 27, 2021
4L8R	Structure of mrna stem-loop, human stem-loop binding protein and 3'hexo ternary complex Descriptor: 3'-5' exoribonuclease 1, HISTONE MRNA STEM-LOOP, Histone RNA hairpin-binding protein Authors: Tan, D, Tong, L. Deposit date: 2013-06-17 Release date: 2013-07-10 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of Histone Mrna Stem-Loop, Human Stem-Loop Binding Protein, and 3'Hexo Ternary Complex. Science, 339, 2013
6H57	Crystal structure of S. cerevisiae DEAH-box RNA helicase Dhr1, essential for small ribosomal subunit biogenesis Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... Authors: Roychowdhury, A, Graille, M. Deposit date: 2018-07-24 Release date: 2019-06-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis. Nucleic Acids Res., 47, 2019
5C0Y	Crystal structure of the Rrp6 catalytic domain bound to poly(U) RNA Descriptor: Exosome complex exonuclease RRP6, MAGNESIUM ION, poly U RNA Authors: Schuch, B, Conti, E. Deposit date: 2015-06-12 Release date: 2015-08-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
4GCW	Crystal structure of RNase Z in complex with precursor tRNA(Thr) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ribonuclease Z, TRNA(THR), ... Authors: Pellegrini, O, Li de la Sierra-Gallay, I, Piton, J, Gilet, L, Condon, C. Deposit date: 2012-07-31 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Activation of tRNA Maturation by Downstream Uracil Residues in B. subtilis Structure, 20, 2012
7Y18	Crystal structure of ribosomal ITS2 pre-rRNA processing complex from Saccharomyces cerevisiae Descriptor: Polynucleotide 5'-hydroxyl-kinase GRC3, Protein LAS1 Authors: Chen, J, Liu, L. Deposit date: 2022-06-07 Release date: 2023-06-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.69 Å) Cite: Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
8SSF	Minimal protein-only/RNA-free Ribonuclease P from Hydrogenobacter thermophilus Descriptor: RNA-free ribonuclease P, SULFATE ION Authors: Mendoza, J, Mallik, L, Wilhelm, C.A, Koutmos, M. Deposit date: 2023-05-08 Release date: 2023-10-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P. J.Biol.Chem., 299, 2023
6KUJ	Structure of influenza D virus polymerase bound to cRNA promoter in class 1 Descriptor: 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ... Authors: Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. Deposit date: 2019-09-02 Release date: 2019-10-02 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation NAT NANOTECHNOL, 2019
4YOE	Structure of UP1 bound to RNA 5'-AGU-3' Descriptor: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ... Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2015-03-11 Release date: 2015-06-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.92 Å) Cite: The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein. J.Mol.Biol., 427, 2015
8SSG	Minimal protein-only/RNA-free Ribonuclease P from Hydrogenobacter thermophilus Descriptor: RNA-free ribonuclease P Authors: Mendoza, J, Wilhelm, C.A, Mallik, L, Koutmos, M. Deposit date: 2023-05-08 Release date: 2023-10-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P. J.Biol.Chem., 299, 2023
5LSO	Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor Descriptor: LYS-SER-ARG-TRP-ASP-GLU, Splicing factor 45 Authors: Jagtap, P.K.A, Garg, D, Sattler, M. Deposit date: 2016-09-05 Release date: 2016-10-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing. J. Med. Chem., 59, 2016
3J7A	Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... Authors: Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. Deposit date: 2014-06-03 Release date: 2014-07-16 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
6JVX	Crystal structure of RBM38 in complex with RNA Descriptor: RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION Authors: Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. Deposit date: 2019-04-17 Release date: 2020-01-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.301 Å) Cite: Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
7Y17	Crystal structure of ribosomal ITS2 pre-rRNA processing complex from Cyberlindnera jadinii Descriptor: LAS1 protein, Polynucleotide 5'-hydroxyl-kinase GRC3 Authors: Chen, J, Liu, L. Deposit date: 2022-06-07 Release date: 2023-06-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.39 Å) Cite: Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
3HOV	Complete RNA polymerase II elongation complex II Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*A*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*T*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', ... Authors: Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. Deposit date: 2009-06-03 Release date: 2009-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOW	Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine Descriptor: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... Authors: Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. Deposit date: 2009-06-03 Release date: 2009-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOY	Complete RNA polymerase II elongation complex VI Descriptor: 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ... Authors: Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. Deposit date: 2009-06-03 Release date: 2009-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOX	Complete RNA polymerase II elongation complex V Descriptor: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*AP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... Authors: Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. Deposit date: 2009-06-03 Release date: 2009-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOU	Complete RNA polymerase II elongation complex I with a T-U mismatch Descriptor: 5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*U*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*U)-3', ... Authors: Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. Deposit date: 2009-06-03 Release date: 2009-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
3HOZ	Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine Descriptor: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*G)-3', ... Authors: Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. Deposit date: 2009-06-03 Release date: 2009-07-28 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009

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