8AXP

Neisseria gonorrhoeae peptidyl-tRNA hydrolase complexed with an XChem hit.

Summary for 8AXP

• Entry DOI: 10.2210/pdb8axp/pdb
• Descriptor: Peptidyl-tRNA hydrolase, N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, hydrolase
• Biological source: Neisseria gonorrhoeae
• Total number of polymer chains: 2
• Total formula weight: 44098.30

Authors

Roe, S.M.,Fearon, D. (deposition date: 2022-08-31, release date: 2022-11-09, Last modification date: 2024-01-31)

• Primary citation: Hassell-Hart, S.,Speranzini, E.,Srikwanjai, S.,Hossack, E.,Roe, S.M.,Fearon, D.,Akinbosede, D.,Hare, S.,Spencer, J.; Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction.; Org.Lett., 24:7924-7927, 2022; PubMed: 36265082; DOI: 10.1021/acs.orglett.2c02996

Experimental method

X-RAY DIFFRACTION (1.83 Å)