5M5X
 
 | | RNA Polymerase I elongation complex 1 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-23 | | Release date: | 2016-12-21 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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5M5Y
 | | RNA Polymerase I elongation complex 2 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | | Deposit date: | 2016-10-23 | | Release date: | 2016-12-21 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular Structures of Transcribing RNA Polymerase I.
Mol. Cell, 64, 2016
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3DLL
 | | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning | | Descriptor: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Wilson, D.N, Schluenzen, F, Harms, J.M, Starosta, A.L, Connell, S.R, Fucini, P. | | Deposit date: | 2008-06-27 | | Release date: | 2008-09-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
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6LT7
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7A5F
 | | Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs | | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | | Deposit date: | 2020-08-21 | | Release date: | 2020-12-23 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
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7ACJ
 | | Structure of translocated trans-translation complex on E. coli stalled ribosome. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | | Deposit date: | 2020-09-11 | | Release date: | 2021-08-18 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structures of tmRNA and SmpB as they transit through the ribosome.
Nat Commun, 12, 2021
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5MQ0
 | | Structure of a spliceosome remodeled for exon ligation | | Descriptor: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | | Authors: | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | | Deposit date: | 2016-12-19 | | Release date: | 2017-01-18 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (4.17 Å) | | Cite: | Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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6WDR
 | | Subunit joining exposes nascent pre-40S rRNA for processing and quality control | | Descriptor: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S10-A, ... | | Authors: | Rai, J, Parker, M.D, Huang, H, Choy, S, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E. | | Deposit date: | 2020-04-01 | | Release date: | 2020-09-30 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7.
Rna, 27, 2021
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5JS1
 | | Human Argonaute2 Bound to an siRNA | | Descriptor: | MAGNESIUM ION, PHENOL, Protein argonaute-2, ... | | Authors: | Schirle, N.T, MacRae, I.J. | | Deposit date: | 2016-05-07 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.499 Å) | | Cite: | Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide.
J.Am.Chem.Soc., 138, 2016
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7ACR
 | | Structure of post-translocated trans-translation complex on E. coli stalled ribosome. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | | Deposit date: | 2020-09-11 | | Release date: | 2021-08-18 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Structures of tmRNA and SmpB as they transit through the ribosome.
Nat Commun, 12, 2021
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5JS2
 | | Human Argonaute-2 Bound to a Modified siRNA | | Descriptor: | MAGNESIUM ION, PHENOL, PHOSPHATE ION, ... | | Authors: | Schirle, N.T, MacRae, I.J. | | Deposit date: | 2016-05-07 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.954 Å) | | Cite: | Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide.
J.Am.Chem.Soc., 138, 2016
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7DU2
 | | RNA polymerase III EC complex in post-translocation state | | Descriptor: | DNA (5'-D(P*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*T)-3'), DNA-directed RNA polymerase III subunit RPC1, ... | | Authors: | Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. | | Deposit date: | 2021-01-07 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structure of human RNA polymerase III elongation complex.
Cell Res., 31, 2021
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7A5J
 | | Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs | | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | | Deposit date: | 2020-08-21 | | Release date: | 2020-12-23 | | Last modified: | 2023-03-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
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8WIB
 | | Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, E- tRNA and RafH. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | | Deposit date: | 2023-09-24 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Nat Commun, 15, 2024
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5YD0
 | | Crystal structure of Schlafen 13 (SLFN13) N'-domain | | Descriptor: | Schlafen 8, ZINC ION | | Authors: | Yang, J.-Y, Gao, S. | | Deposit date: | 2017-09-09 | | Release date: | 2018-03-28 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.182 Å) | | Cite: | Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control
Nat Commun, 9, 2018
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5C0Y
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5MPS
 | | Structure of a spliceosome remodeled for exon ligation | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | | Deposit date: | 2016-12-18 | | Release date: | 2017-01-18 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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7XW2
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4V9E
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6H57
 | | Crystal structure of S. cerevisiae DEAH-box RNA helicase Dhr1, essential for small ribosomal subunit biogenesis | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Roychowdhury, A, Graille, M. | | Deposit date: | 2018-07-24 | | Release date: | 2019-06-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis.
Nucleic Acids Res., 47, 2019
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6RFL
 | | Structure of the complete Vaccinia DNA-dependent RNA polymerase complex | | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | | Authors: | Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U. | | Deposit date: | 2019-04-15 | | Release date: | 2019-12-11 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Cell, 179, 2019
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5TGM
 | | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | | Authors: | Melnikov, S, Mailliot, J, Yusupov, M. | | Deposit date: | 2016-09-28 | | Release date: | 2017-01-18 | | Last modified: | 2022-12-07 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
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5D0B
 | | Crystal structure of epoxyqueuosine reductase with a tRNA-TYR epoxyqueuosine-modified tRNA stem loop | | Descriptor: | COBALAMIN, Epoxyqueuosine reductase, GLYCEROL, ... | | Authors: | Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. | | Deposit date: | 2015-08-03 | | Release date: | 2016-09-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.645 Å) | | Cite: | Molecular basis of cobalamin-dependent RNA modification.
Nucleic Acids Res., 44, 2016
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7V6C
 | | Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | | Descriptor: | Dicer-2, isoform A, R2D2, ... | | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | | Deposit date: | 2021-08-20 | | Release date: | 2022-03-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
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5K77
 | | Dbr1 in complex with 7-mer branched RNA | | Descriptor: | FE (II) ION, HYDROXIDE ION, RNA lariat debranching enzyme, ... | | Authors: | Clark, N.E, Taylor, A.B, Hart, P.J. | | Deposit date: | 2016-05-25 | | Release date: | 2016-12-07 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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