PDB: 294 resultsInfo pagesStatus searchChemie searchBIRD

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6UA4	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (3/4 compressed, 1/4 extended) segment reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-10 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.65 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U8R	Human IMPDH2 treated with ATP, IMP, and NAD+. Bent (1/4 compressed, 3/4 extended) segment reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ... Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-05 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.91 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U9O	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Fully compressed filament segment reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-09 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UA5	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free interfacial octamer reconstruction. Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-10 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U8S	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Filament assembly interface reconstruction. Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-05 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
4DQW	Crystal Structure Analysis of PA3770 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Inosine-5'-monophosphate dehydrogenase, ... Authors: Labesse, G, Munier-Lehmann, H. Deposit date: 2012-02-16 Release date: 2013-03-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.51 Å) Cite: MgATP Regulates Allostery and Fiber Formation in IMPDHs. Structure, 21, 2013
6UAJ	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free canonical octamer reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-10 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UC2	Human IMPDH2 treated with ATP and 2 mM GTP. Free canonical octamer reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2 Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.48 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UA2	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-10 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
4FEZ	Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... Authors: Osipiuk, J, Maltseva, N, Makowska-Grzyska, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-05-30 Release date: 2012-06-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant. To be Published
4FXS	Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, MYCOPHENOLIC ACID, ... Authors: Osipiuk, J, Maltseva, N, Makowska-Grzyska, M, Jedrzejczak, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-07-03 Release date: 2012-07-25 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid. To be Published
8PW3	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) apo form Descriptor: Inosine-5'-monophosphate dehydrogenase Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-07-19 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.507 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8Q65	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP-bound form Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-08-10 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8QQR	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, super-compressed Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5',3'-TETRAPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-10-06 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.73 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8QQQ	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+GTP-bound form, compressed Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-10-06 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.43 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8QQX	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+IMP-bound form, half-extended Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-10-06 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8QQP	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+GTP-bound form, super-compressed Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-10-06 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.35 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8S5I	Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE Authors: McCorvie, T.J, Yue, W.W. Deposit date: 2024-02-23 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8S5H	Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, helical reconstruction Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE Authors: McCorvie, T.J, Yue, W.W. Deposit date: 2024-02-23 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8S5J	Full-length human cystathionine beta-synthase, basal state, helical reconstruction Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE Authors: McCorvie, T.J, Yue, W.W. Deposit date: 2024-02-23 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8S5K	Full-length human cystathionine beta-synthase, basal state, single particle reconstruction Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE Authors: McCorvie, T.J, Yue, W.W. Deposit date: 2024-02-23 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8S5L	Full-length human cystathionine beta-synthase, basal state, partially degraded tetramer Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE Authors: McCorvie, T.J, Yue, W.W. Deposit date: 2024-02-23 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8S5M	Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction Descriptor: Cystathionine beta-synthase, S-ADENOSYLMETHIONINE Authors: McCorvie, T.J, Yue, W.W. Deposit date: 2024-02-23 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (4 Å) Cite: Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun, 15, 2024
8QQV	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+IMP-bound form, extended Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-10-06 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024
8QQW	Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP-bound form, compressed Descriptor: Inosine-5'-monophosphate dehydrogenase Authors: Bulvas, O, Kouba, T, Pichova, I. Deposit date: 2023-10-06 Release date: 2024-08-14 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase. Nat Commun, 15, 2024

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