1DXF
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1DY0
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8OQ7
| CryoEM structure of human rho1 GABAA receptor in complex with inhibitor TPMPA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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1E0B
| Chromo shadow domain from fission yeast swi6 protein. | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, SWI6 PROTEIN | Authors: | Cowieson, N.P, Partridge, J.F, Allshire, R.C, Mclaughlin, P.J. | Deposit date: | 2000-03-16 | Release date: | 2000-05-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Dimerisation of Chromo Shadow Domain and Distinctions from the Chromodomain as Revealed by Structural Analysis Curr.Biol., 10, 2000
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1DWG
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1E1A
| Crystal structure of DFPase from Loligo vulgaris | Descriptor: | CALCIUM ION, DIISOPROPYLFLUOROPHOSPHATASE | Authors: | Koepke, J, Scharff, E.I, Fritzsch, G, Luecke, C, Rueterjans, H. | Deposit date: | 2000-04-28 | Release date: | 2001-06-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Diisopropylfluorophosphatase from Loligo Vulgaris Structure, 9, 2001
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6UVF
| Crystal structure of BCL-XL bound to compound 12: (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-((cyclohexylmethyl)sulfonyl)propanoic acid | Descriptor: | (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-((cyclohexylmethyl)sulfonyl)propanoic acid, 1,2-ETHANEDIOL, Bcl-2-like protein 1, ... | Authors: | Roy, M.J, Lessene, G, Czabotar, P.E. | Deposit date: | 2019-11-02 | Release date: | 2021-05-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2. J.Med.Chem., 64, 2021
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1DWT
| Photorelaxed horse heart MYOGLOBIN CO complex | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Chu, K, Vojtechovsky, J, McMahon, B.H, Sweet, R.M, Berendzen, J, Schlichting, I. | Deposit date: | 1999-12-12 | Release date: | 2000-03-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of a New Ligand Binding Intermediate in Wildtype Carbonmonoxy Myoglobin Nature, 403, 2000
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8HC2
| SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 1 YB9-258 Fab (1 RBD up) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of YB9-258 Fab, ... | Authors: | Liu, B, Gao, X, Chen, Q, Li, Z, Su, M, He, J, Xiong, X. | Deposit date: | 2022-11-01 | Release date: | 2023-01-25 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (6.21 Å) | Cite: | Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants. Nat Commun, 14, 2023
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1E2Y
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6UVG
| Crystal structure of BCL-XL bound to compound 13: (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid | Descriptor: | (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid, 1,2-ETHANEDIOL, Bcl-2-like protein 1, ... | Authors: | Roy, M.J, Lessene, G, Czabotar, P.E. | Deposit date: | 2019-11-02 | Release date: | 2021-05-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2. J.Med.Chem., 64, 2021
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8OQA
| CryoEM structure of human rho1 GABAA receptor in complex with GABA and picrotoxin | Descriptor: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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1E15
| Chitinase B from Serratia Marcescens | Descriptor: | CHITINASE B | Authors: | Van Aalten, D.M.F, Synstad, B, Brurberg, M.B, Hough, E, Riise, B.W, Eijsink, V.G.H, Wierenga, R.K. | Deposit date: | 2000-04-18 | Release date: | 2000-08-18 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a Two-Domain Chitotriosidase from Serratia Marcescens at 1.9 Angstrom Resoltuion Proc.Natl.Acad.Sci.USA, 97, 2000
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8OQ8
| CryoEM structure of human rho1 GABAA receptor in complex with pore blocker picrotoxin | Descriptor: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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1E22
| LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM complexed with lysine and the non-hydrolysable atp analogue amp-pcp | Descriptor: | GLYCEROL, LYSINE, LYSYL-TRNA SYNTHETASE, ... | Authors: | Desogus, G, Todone, F, Brick, P, Onesti, S. | Deposit date: | 2000-05-15 | Release date: | 2000-07-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction Biochemistry, 39, 2000
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1E0D
| UDP-N-Acetylmuramoyl-L-Alanine:D-Glutamate Ligase | Descriptor: | SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE | Authors: | Fanchon, E, Bertrand, J, Chantalat, L, Dideberg, O. | Deposit date: | 2000-03-24 | Release date: | 2000-06-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | "Open" Structures of Murd: Domain Movements and Structural Similarities with Folylpolyglutamate Synthetase. J.Mol.Biol., 301, 2000
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1E0O
| CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, FIBROBLAST GROWTH FACTOR 1, FIBROBLAST GROWTH FACTOR RECEPTOR 2, ... | Authors: | Pellegrini, L, Burke, D.F, von Delft, F, Mulloy, B, Blundell, T.L. | Deposit date: | 2000-04-03 | Release date: | 2000-10-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Ligand and Heparin Nature, 407, 2000
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8OP9
| CryoEM structure of human rho1 GABAA receptor in complex with GABA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-06 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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1E2R
| CYTOCHROME CD1 NITRITE REDUCTASE, REDUCED AND CYANIDE BOUND | Descriptor: | CYANIDE ION, GLYCEROL, HEME C, ... | Authors: | Fulop, V. | Deposit date: | 2000-05-24 | Release date: | 2000-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | X-Ray Crystallographic Study of Cyanide Binding Provides Insights Into the Structure-Function Relationship for Cytochrome Cd1 Nitrite Reductase from Paracoccus Pantotrophus. J.Biol.Chem., 275, 2000
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1E4O
| Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question | Descriptor: | MALTODEXTRIN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Watson, K.A, McCleverty, C, Geremia, S, Cottaz, S, Driguez, H, Johnson, L.N. | Deposit date: | 2000-07-11 | Release date: | 2000-08-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Phosphorylase Recognition and Phosphorylysis of its Oligosaccharide Substrate: Answers to a Long Outstanding Question Embo J., 18, 1999
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1DWJ
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8GYY
| Bifunctional xylosidase/glucosidase LXYL with intermediate substrate xylose, 120 seconds | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, L.Y. | Deposit date: | 2022-09-24 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Bifunctional xylosidase/glucosidase LXYL with intermediate substrate xylose To Be Published
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1DWA
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1DWV
| MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-hydroxyarginine and 4-amino tetrahydrobiopterin | Descriptor: | 2,4-DIAMINO-6-[2,3-DIHYDROXY-PROP-3-YL]-5,6,7,8-TETRAHYDROPTERIDINE, N-OMEGA-HYDROXY-L-ARGININE, NITRIC OXIDE SYNTHASE, ... | Authors: | Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. | Deposit date: | 1999-12-14 | Release date: | 2000-02-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins Biochemistry, 39, 2000
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6VIM
| P. putida mandelate racemase co-crystallized with phenylboronic acid | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Mandelate racemase, ... | Authors: | Grandinetti, L, Sharma, A.N, Bearne, S.L, St Maurice, M. | Deposit date: | 2020-01-13 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center. Biochemistry, 59, 2020
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