3J78
 
 | | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | Authors: | Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2014-05-29 | | Release date: | 2014-08-06 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.3 Å) | | Cite: | Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
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7B9V
 | | Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound | | Descriptor: | 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... | | Authors: | Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. | | Deposit date: | 2020-12-14 | | Release date: | 2021-03-10 | | Last modified: | 2021-04-14 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
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3J6Y
 | | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | Authors: | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2014-04-16 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2WH0
 | | Recognition of an intrachain tandem 14-3-3 binding site within protein kinase C epsilon | | Descriptor: | 14-3-3 PROTEIN ZETA/DELTA, CALCIUM ION, PROTEIN KINASE C EPSILON TYPE, ... | | Authors: | Kostelecky, B, Saurin, A.T, Purkiss, A, Parker, P.J, McDonald, N.Q. | | Deposit date: | 2009-04-28 | | Release date: | 2009-08-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon.
Embo Rep., 10, 2009
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4NNJ
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4I2W
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5L4K
 | | The human 26S proteasome lid | | Descriptor: | 26S proteasome complex subunit DSS1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | | Authors: | Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F. | | Deposit date: | 2016-05-25 | | Release date: | 2016-09-07 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8U39
 | | Structure of Human Mitochondrial Chaperonin V72I mutant | | Descriptor: | 60 kDa heat shock protein, mitochondrial | | Authors: | Chen, L, Wang, J. | | Deposit date: | 2023-09-07 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure and molecular dynamic simulations explain the enhanced stability and ATP activity of the pathological chaperonin mutant.
Structure, 32, 2024
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5M32
 | | Human 26S proteasome in complex with Oprozomib | | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | | Authors: | Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H. | | Deposit date: | 2016-10-14 | | Release date: | 2017-07-05 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
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5GMK
 | | Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution | | Descriptor: | 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y. | | Deposit date: | 2016-07-14 | | Release date: | 2016-08-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution
Science, 353, 2016
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8G7M
 | | ATP-bound mtHsp60 V72I focus | | Descriptor: | 60 kDa heat shock protein, mitochondrial, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G7L
 | | ATP-bound mtHsp60 V72I | | Descriptor: | 60 kDa heat shock protein, mitochondrial, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G7O
 | | ATP- and mtHsp10-bound mtHsp60 V72I focus | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G7N
 | | ATP- and mtHsp10-bound mtHsp60 V72I | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G7K
 | | mtHsp60 V72I apo focus | | Descriptor: | 60 kDa heat shock protein, mitochondrial | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G7J
 | | mtHsp60 V72I apo | | Descriptor: | 60 kDa heat shock protein, mitochondrial | | Authors: | Braxton, J.R, Shao, H, Tse, E, Gestwicki, J.E, Southworth, D.R. | | Deposit date: | 2023-02-16 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.
Biorxiv, 2023
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8G1P
 | | Co-crystal structure of Compound 11 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | | Descriptor: | (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | Authors: | Ghimire Rijal, S, Wurz, R.P, Vaish, A. | | Deposit date: | 2023-02-02 | | Release date: | 2023-07-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation.
Nat Commun, 14, 2023
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7L7S
 | | Human mitochondrial chaperonin mHsp60 | | Descriptor: | 60 kDa heat shock protein, mitochondrial | | Authors: | Chen, L, Wang, J.C.Y. | | Deposit date: | 2020-12-30 | | Release date: | 2021-08-25 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.
Sci Rep, 11, 2021
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8OTZ
 | | 48-nm repeat of the native axonemal doublet microtubule from bovine sperm | | Descriptor: | ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ... | | Authors: | Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T. | | Deposit date: | 2023-04-21 | | Release date: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural specializations of the sperm tail.
Cell, 186, 2023
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6HT7
 | | Crystal structure of the WT human mitochondrial chaperonin (ADP:BeF3)14 complex | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Jebara, F, Patra, M, Azem, A, Hirsch, J. | | Deposit date: | 2018-10-03 | | Release date: | 2020-04-29 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Crystal structure of the WT human mitochondrial football Hsp60-Hsp10(ADPBeFx)14 complex
Nat Commun, 2020
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5XY9
 | | Structure of the MST4 and 14-3-3 complex | | Descriptor: | 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... | | Authors: | Shi, Z.B, Zhou, Z.C. | | Deposit date: | 2017-07-06 | | Release date: | 2018-07-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | Structure of the MST4 and 14-3-3 complex
To Be Published
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4PJ1
 | | Crystal structure of the human mitochondrial chaperonin symmetrical 'football' complex | | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | | Authors: | Frolow, F, Azem, A, Nisemblat, S. | | Deposit date: | 2014-05-10 | | Release date: | 2015-04-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Crystal structure of the human mitochondrial chaperonin symmetrical football complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3OGL
 | | Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron | | Descriptor: | Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, N-({(1R,2S)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetyl)-L-isoleucine, ... | | Authors: | Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N. | | Deposit date: | 2010-08-17 | | Release date: | 2010-10-13 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
Nature, 468, 2010
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3OGK
 | | Structure of COI1-ASK1 in complex with coronatine and an incomplete JAZ1 degron | | Descriptor: | (1S,2S)-2-ethyl-1-({[(3aS,4S,6R,7aS)-6-ethyl-1-oxooctahydro-1H-inden-4-yl]carbonyl}amino)cyclopropanecarboxylic acid, Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, ... | | Authors: | Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N. | | Deposit date: | 2010-08-16 | | Release date: | 2010-10-13 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
Nature, 468, 2010
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5Y53
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