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7SBB
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BU of 7sbb by Molmil
Structure of type I-D Cascade bound to a ssRNA target
Descriptor: Cas10d, Cas11d, Cas5d, ...
Authors:Schwartz, E.A, Taylor, D.W.
Deposit date:2021-09-24
Release date:2022-06-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural rearrangements allow nucleic acid discrimination by type I-D Cascade.
Nat Commun, 13, 2022
4N3W
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BU of 4n3w by Molmil
Crystal Structure of the Bromodomain-PHD Finger Module of Human Transcriptional Co-Activator CBP in complex with Acetylated Histone 4 Peptide (H4K20ac).
Descriptor: CREB-binding protein, Histone H4 peptide, ZINC ION
Authors:Plotnikov, A.N, Yang, S, Zhou, M.-M.
Deposit date:2013-10-07
Release date:2014-01-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP.
Structure, 22, 2014
1V1K
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BU of 1v1k by Molmil
CDK2 IN COMPLEX WITH A DISUBSTITUTED 4, 6-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR
Descriptor: (2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2
Authors:Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E.
Deposit date:2004-04-16
Release date:2004-05-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines
Bioorg.Med.Chem.Lett., 13, 2003
3F6V
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BU of 3f6v by Molmil
Crystal structure of Possible transcriptional regulator for arsenical resistance
Descriptor: MAGNESIUM ION, Possible transcriptional regulator, ArsR family protein
Authors:Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-11-06
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of Possible transcriptional regulator for arsenical resistance from Rhodococcus sp.
To be Published
1V06
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BU of 1v06 by Molmil
AXH domain of the transcription factor HBP1 from M.musculus
Descriptor: HMG BOX-CONTAINING PROTEIN 1
Authors:De Chiara, C, Kelly, G, Pastore, A.
Deposit date:2004-03-24
Release date:2005-04-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Axh Domain Adopts Alternative Folds the Solution Structure of Hbp1 Axh.
Structure, 13, 2005
6W6D
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BU of 6w6d by Molmil
Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with SGC6870 inhibitor
Descriptor: (5R)-4-(5-bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one, Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Halabelian, L, Zeng, H, Dong, A, Jin, J, Shen, Y, Kaniskan, H.U, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2020-03-16
Release date:2020-04-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.
J.Med.Chem., 64, 2021
8C96
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BU of 8c96 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C93
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BU of 8c93 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C99
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BU of 8c99 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ...
Authors:Nikolay, R, Qin, B, Lauer, S.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C9B
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BU of 8c9b by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L22, 50S ribosomal protein L24, ...
Authors:Nikolay, R, Qin, B, Lauer, S.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C8Z
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BU of 8c8z by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C92
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BU of 8c92 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C94
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BU of 8c94 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C98
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BU of 8c98 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C9A
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BU of 8c9a by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L22, 50S ribosomal protein L23, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.86 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C97
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BU of 8c97 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L17, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C90
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BU of 8c90 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C95
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BU of 8c95 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.92 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
6HL1
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BU of 6hl1 by Molmil
Crystal Structure of Farnesoid X receptor (FXR) with bound NCoA-2 peptide and CDCA
Descriptor: Bile acid receptor, CHENODEOXYCHOLIC ACID, NCoA-2 peptide (Nuclear receptor coactivator 2), ...
Authors:Kudlinzki, D, Merk, D, Linhard, V.L, Saxena, K, Schubert-Zsilavecz, M, Schwalbe, H.
Deposit date:2018-09-10
Release date:2019-05-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Molecular tuning of farnesoid X receptor partial agonism.
Nat Commun, 10, 2019
3BJ6
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BU of 3bj6 by Molmil
Crystal structure of MarR family transcription regulator SP03579
Descriptor: ETHANOL, Transcriptional regulator, MarR family
Authors:Kim, Y, Volkart, L, Keigher, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-12-03
Release date:2007-12-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Structure of MarR family Transcription Regulator SP03579.
To be Published
7MDZ
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BU of 7mdz by Molmil
80S rabbit ribosome stalled with benzamide-CHX
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ...
Authors:Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B.
Deposit date:2021-04-06
Release date:2021-09-01
Last modified:2021-09-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.
J.Am.Chem.Soc., 143, 2021
7KI6
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BU of 7ki6 by Molmil
Structure of the HeV F glycoprotein in complex with the 1F5 neutralizing antibody
Descriptor: 1F5 Fab light chain, 1F5 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dang, H.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2020-10-23
Release date:2021-05-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins.
Nat.Struct.Mol.Biol., 28, 2021
7KI4
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BU of 7ki4 by Molmil
Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody
Descriptor: 12B2 Fab light chain, 12B2 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dang, H.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2020-10-23
Release date:2021-05-05
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins.
Nat.Struct.Mol.Biol., 28, 2021
7NWH
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BU of 7nwh by Molmil
Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S.
Descriptor: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C.
Deposit date:2021-03-16
Release date:2021-07-07
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
3G1C
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BU of 3g1c by Molmil
The crystal structure of a TrpR like protein from Eubacterium eligens ATCC 27750
Descriptor: MAGNESIUM ION, The TrpR like protein from Eubacterium eligens ATCC 27750
Authors:Zhang, R, Hendricks, R, Freeman, L, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-01-29
Release date:2009-02-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of a TrpR like protein from Eubacterium eligens ATCC 27750
To be Published

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