2Z28
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![BU of 2z28 by Molmil](/molmil-images/mine/2z28) | Thr109Val dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2Z2B
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2Z25
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![BU of 2z25 by Molmil](/molmil-images/mine/2z25) | Thr110Val dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2Z27
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![BU of 2z27 by Molmil](/molmil-images/mine/2z27) | Thr109Ser dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2Z2A
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![BU of 2z2a by Molmil](/molmil-images/mine/2z2a) | Thr109Gly dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2Z29
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![BU of 2z29 by Molmil](/molmil-images/mine/2z29) | Thr109Ala dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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2QS8
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![BU of 2qs8 by Molmil](/molmil-images/mine/2qs8) | Crystal structure of a Xaa-Pro dipeptidase with bound methionine in the active site | Descriptor: | MAGNESIUM ION, METHIONINE, Xaa-Pro Dipeptidase | Authors: | Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-07-30 | Release date: | 2007-08-21 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes. Biochemistry, 48, 2009
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2P53
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![BU of 2p53 by Molmil](/molmil-images/mine/2p53) | Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D273N mutant complexed with N-acetyl phosphonamidate-d-glucosamine-6-phosphate | Descriptor: | 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION | Authors: | Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C. | Deposit date: | 2007-03-14 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase. Biochemistry, 46, 2007
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2P50
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![BU of 2p50 by Molmil](/molmil-images/mine/2p50) | Crystal structure of N-acetyl-D-Glucosamine-6-Phosphate deacetylase liganded with Zn | Descriptor: | N-acetylglucosamine-6-phosphate deacetylase, ZINC ION | Authors: | Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C. | Deposit date: | 2007-03-14 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase. Biochemistry, 46, 2007
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2PLM
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![BU of 2plm by Molmil](/molmil-images/mine/2plm) | Crystal structure of the protein TM0936 from Thermotoga maritima complexed with ZN and S-inosylhomocysteine | Descriptor: | (2S)-2-AMINO-4-({[(2S,3S,4R,5R)-3,4-DIHYDROXY-5-(6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)TETRAHYDROFURAN-2-YL]METHYL}THIO)BUTANOIC ACID, Uncharacterized protein, ZINC ION | Authors: | Fedorov, A.A, Fedorov, E.V, Hermann, J.C, Marti-Arbona, R, Shoichet, B.K, Raushel, F.M, Almo, S.C. | Deposit date: | 2007-04-20 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-based activity prediction for an enzyme of unknown function Nature, 448, 2007
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2EG6
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2EG8
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![BU of 2eg8 by Molmil](/molmil-images/mine/2eg8) | The crystal structure of E. coli dihydroorotase complexed with 5-fluoroorotic acid | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-02-28 | Release date: | 2007-07-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design J.Mol.Biol., 370, 2007
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2EG7
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![BU of 2eg7 by Molmil](/molmil-images/mine/2eg7) | The crystal structure of E. coli dihydroorotase complexed with HDDP | Descriptor: | 2-OXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4,6-DICARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-02-28 | Release date: | 2007-07-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design J.Mol.Biol., 370, 2007
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2Q09
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![BU of 2q09 by Molmil](/molmil-images/mine/2q09) | Crystal structure of Imidazolonepropionase from environmental sample with bound inhibitor 3-(2,5-Dioxo-imidazolidin-4-yl)-propionic acid | Descriptor: | 3-[(4S)-2,5-DIOXOIMIDAZOLIDIN-4-YL]PROPANOIC ACID, FE (III) ION, Imidazolonepropionase | Authors: | Tyagi, R, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-05-21 | Release date: | 2007-06-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | A common catalytic mechanism for proteins of the HutI family. Biochemistry, 47, 2008
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2PUZ
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![BU of 2puz by Molmil](/molmil-images/mine/2puz) | Crystal structure of Imidazolonepropionase from Agrobacterium tumefaciens with bound product N-formimino-L-Glutamate | Descriptor: | CHLORIDE ION, FE (III) ION, Imidazolonepropionase, ... | Authors: | Tyagi, R, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-05-09 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | X-ray structure of imidazolonepropionase from Agrobacterium tumefaciens at 1.87 A resolution. Proteins, 69, 2007
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2UZ9
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![BU of 2uz9 by Molmil](/molmil-images/mine/2uz9) | Human guanine deaminase (guaD) in complex with zinc and its product Xanthine. | Descriptor: | GUANINE DEAMINASE, XANTHINE, ZINC ION | Authors: | Moche, M, Welin, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-04-26 | Release date: | 2007-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Human Guanine Deaminase (Guad) in Complex with Zinc and its Product Xhantine To be Published
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2P9B
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2E25
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![BU of 2e25 by Molmil](/molmil-images/mine/2e25) | The Crystal Structure of the T109S mutant of E. coli Dihydroorotase complexed with an inhibitor 5-fluoroorotate | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2006-11-08 | Release date: | 2007-03-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form Acta Crystallogr.,Sect.F, 63, 2007
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2OOF
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2OOD
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2OGJ
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![BU of 2ogj by Molmil](/molmil-images/mine/2ogj) | Crystal structure of a dihydroorotase | Descriptor: | Dihydroorotase, IMIDAZOLE, ZINC ION | Authors: | Sugadev, R, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-01-05 | Release date: | 2007-02-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Crystal structure of a dihydroorotase To be Published
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2IMR
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2G3F
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![BU of 2g3f by Molmil](/molmil-images/mine/2g3f) | Crystal Structure of imidazolonepropionase complexed with imidazole-4-acetic acid sodium salt, a substrate homologue | Descriptor: | 2H-IMIDAZOL-4-YLACETIC ACID, Imidazolonepropionase, ZINC ION | Authors: | Yu, Y, Liang, Y.H, Su, X.D. | Deposit date: | 2006-02-19 | Release date: | 2006-09-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis J.Biol.Chem., 281, 2006
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2BB0
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![BU of 2bb0 by Molmil](/molmil-images/mine/2bb0) | |
2I9U
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![BU of 2i9u by Molmil](/molmil-images/mine/2i9u) | |