2E25
The Crystal Structure of the T109S mutant of E. coli Dihydroorotase complexed with an inhibitor 5-fluoroorotate
Summary for 2E25
| Entry DOI | 10.2210/pdb2e25/pdb |
| Related | 1XGE |
| Descriptor | Dihydroorotase, ZINC ION, 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, ... (4 entities in total) |
| Functional Keywords | tim barrel, hydrolase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 39061.96 |
| Authors | Lee, M.,Maher, M.J.,Guss, J.M. (deposition date: 2006-11-08, release date: 2007-03-13, Last modification date: 2023-11-15) |
| Primary citation | Lee, M.,Maher, M.J.,Guss, J.M. Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form Acta Crystallogr.,Sect.F, 63:154-161, 2007 Cited by PubMed: 17329804DOI: 10.1107/S1744309107004009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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