2E25
The Crystal Structure of the T109S mutant of E. coli Dihydroorotase complexed with an inhibitor 5-fluoroorotate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydroorotase | polymer | 347 | 38757.1 | 1 | UniProt (P05020) Pfam (PF01979) In PDB | Escherichia coli | DHOase |
| 2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 174.1 | 1 | Chemie (FOT) | |||
| 4 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 1 - 347 (UniProt: P05020)
| PDB | External Database | Details |
|---|---|---|
| Kcx 102 | Lys 102 | modified residue |
| Ser 109 | Thr 109 | engineered mutation |
| Val 119 | Ile 119 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38757.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 304.9 | |
| All* | Total formula weight | 39062.0 |
