PDB: 659 resultsInfo pagesStatus searchChemie searchBIRD

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3EGH	Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R Descriptor: GLYCEROL, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ... Authors: Ragusa, M.J, Page, R, Peti, W. Deposit date: 2008-09-10 Release date: 2010-03-23 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Nat.Struct.Mol.Biol., 17, 2010
2KA9	Solution structure of PSD-95 PDZ12 complexed with cypin peptide Descriptor: Disks large homolog 4, cypin peptide Authors: Wang, W.N, Weng, J.W, Zhang, X, Liu, M.L, Zhang, M.J. Deposit date: 2008-11-03 Release date: 2009-06-23 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Creating conformational entropy by increasing interdomain mobility in ligand binding regulation: a revisit to N-terminal tandem PDZ domains of PSD-95 J.Am.Chem.Soc., 131, 2009
2KAW	NMR structure of the mDvl1 PDZ domain in complex with its inhibitor Descriptor: Segment polarity protein dishevelled homolog DVL-1, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid Authors: Lee, H.J, Shao, Y, Wang, N.X, Shi, D.L, Zheng, J.J. Deposit date: 2008-11-17 Release date: 2009-09-15 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled. Angew.Chem.Int.Ed.Engl., 48, 2009
2W4F	CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1 Descriptor: 1,2-ETHANEDIOL, PROTEIN LAP4 Authors: Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U. Deposit date: 2008-11-25 Release date: 2008-12-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal Structure of the First Pdz Domain of Human Scrib1 To be Published
2KBS	Solution structure of harmonin PDZ2 in complex with the carboxyl tail peptide of cadherin23 Descriptor: Harmonin, octameric peptide from Cadherin-23 Authors: Pan, L, Yan, J, Wu, L, Zhang, M. Deposit date: 2008-12-05 Release date: 2009-03-31 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23 Proc.Natl.Acad.Sci.USA, 106, 2009
3FY5	Dishevelled PDZ domain homodimer Descriptor: Segment polarity protein dishevelled homolog DVL-2 Authors: Earnest, T, Friedland, N, Hung, L.-W, Moon, R. Deposit date: 2009-01-21 Release date: 2009-09-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite:
3GCO	Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYQF OMP peptide Descriptor: DNRDGNVYQF peptide, Protease degS Authors: Sohn, J, Grant, R.A, Sauer, R.T. Deposit date: 2009-02-22 Release date: 2009-03-31 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2.798 Å) Cite: OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism. Structure, 17, 2009
3GCN	Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with OMP peptide (YQF) Descriptor: Protease degS, YQF peptide Authors: Sohn, J, Sauer, R.T, Grant, R.A. Deposit date: 2009-02-22 Release date: 2009-03-31 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.002 Å) Cite: Mechanisms of allosteric activation of the DegS protease by OMP-peptide binding and protein-substrate binding To be Published
3GDS	Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYYF peptide Descriptor: DNRDGNVYYF peptide, Protease degS Authors: Sohn, J, Grant, R.A, Sauer, R.T. Deposit date: 2009-02-24 Release date: 2009-03-31 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2.85 Å) Cite: OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism. Structure, 17, 2009
3GDU	Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YRF peptide Descriptor: DegS protease, YRF peptide Authors: Sohn, J, Grant, R.A, Sauer, R.T. Deposit date: 2009-02-24 Release date: 2009-03-31 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3 Å) Cite: OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism. Structure, 17, 2009
3GDV	Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YQF peptide Descriptor: DegS protease, YQF peptide Authors: Sohn, J, Grant, R.A, Sauer, R.T. Deposit date: 2009-02-24 Release date: 2009-03-31 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2.489 Å) Cite: OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism. Structure, 17, 2009
3GGE	Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2 Descriptor: GLYCEROL, PDZ domain-containing protein GIPC2, SULFATE ION Authors: Chaikuad, A, Hozjan, V, Yue, W, Cooper, C, Elkins, J, Pike, A.C.W, Roos, A.K, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) Deposit date: 2009-02-27 Release date: 2009-03-24 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2 To be Published
2KG2	Solution structure of a PDZ protein Descriptor: Tax1-binding protein 3 Authors: Durney, M.A, Birrane, G, Anklin, C, Soni, A, Ladias, J.A.A. Deposit date: 2009-03-02 Release date: 2010-01-19 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the human Tax-interacting protein-1. J.Biomol.Nmr, 45, 2009
3GJ9	crystal structure of TIP-1 in complex with c-terminal of Kir2.3 Descriptor: C-terminal peptide from Inward rectifier potassium channel 4, CHLORIDE ION, Tax1-binding protein 3, ... Authors: Shen, Y. Deposit date: 2009-03-08 Release date: 2009-12-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Molecular mechanism of inward rectifier potassium channel 2.3 regulation by tax-interacting protein-1 J.Mol.Biol., 392, 2009
3GSL	Crystal structure of PSD-95 tandem PDZ domains 1 and 2 Descriptor: Disks large homolog 4 Authors: Sainlos, M, Olivier, N.B, Imperiali, B. Deposit date: 2009-03-27 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization. Nat.Chem.Biol., 7, 2011
2KJD	Solution structure of extended PDZ2 domain from NHERF1 (150-270) Descriptor: Sodium/hydrogen exchange regulatory cofactor NHE-RF1 Authors: Bhattacharya, S, Cowburn, D, Bu, Z. Deposit date: 2009-05-27 Release date: 2009-12-29 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: A dynamic intramolecular conformational switch autoregulates the scaffolding protein NHERF1 To be Published
3HPM	Oxidized dimeric PICK1 PDZ C46G mutant in complex with the carboxyl tail peptide of GluR2 Descriptor: PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT Authors: Yu, J, Shi, Y, Zhang, M. Deposit date: 2009-06-04 Release date: 2010-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain. Biochemistry, 49, 2010
3HPK	Oxidized dimeric PICK1 PDZ in complex with the carboxyl tail peptide of GluR2 Descriptor: GLYCEROL, PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT Authors: Yu, J, Shi, Y, Zhang, M. Deposit date: 2009-06-04 Release date: 2010-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain. Biochemistry, 49, 2010
3HVQ	Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Neurabin Descriptor: GLYCEROL, MANGANESE (II) ION, Neurabin-1, ... Authors: Critton, D.A, Ragusa, M.J, Page, R, Peti, W. Deposit date: 2009-06-16 Release date: 2010-03-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Nat.Struct.Mol.Biol., 17, 2010
2WL7	Crystal structure of the PSD93 PDZ1 domain Descriptor: CHLORIDE ION, DISKS LARGE HOMOLOG 2, SULFATE ION Authors: Fiorentini, M, Kallehauge, A, Kristensen, O, Kastrup, J.S, Gajhede, M. Deposit date: 2009-06-22 Release date: 2010-01-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.028 Å) Cite: Structure of the First Pdz Domain of Human Psd-93. Acta Crystallogr.,Sect.F, 65, 2009
3I4W	Crystal Structure of the third PDZ domain of PSD-95 Descriptor: ACETATE ION, Disks large homolog 4 Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2009-07-03 Release date: 2010-04-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures J.Struct.Biol., 170, 2010
3ID2	Crystal Structure of RseP PDZ2 domain Descriptor: IODIDE ION, Regulator of sigma E protease Authors: Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. Deposit date: 2009-07-20 Release date: 2009-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.089 Å) Cite: Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
3ID4	Crystal Structure of RseP PDZ2 domain fused GKASPV peptide Descriptor: Regulator of sigma E protease Authors: Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. Deposit date: 2009-07-20 Release date: 2009-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.604 Å) Cite: Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
3ID3	Crystal Structure of RseP PDZ2 I304A domain Descriptor: Regulator of sigma E protease Authors: Li, X, Wang, B, Feng, L, Wang, J, Shi, Y. Deposit date: 2009-07-20 Release date: 2009-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage Proc.Natl.Acad.Sci.USA, 106, 2009
3JXT	Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand Descriptor: ACETATE ION, Disks large homolog 3, Voltage-dependent calcium channel gamma-2 subunit Authors: Sainlos, M, Olivier, N.B, Imperiali, B. Deposit date: 2009-09-21 Release date: 2010-09-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Caged mono- and divalent ligands for light-assisted disruption of PDZ domain-mediated interactions. J.Am.Chem.Soc., 135, 2013

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