PDB: 237 resultsInfo pagesStatus searchChemie searchBIRD

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4BCI	Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor Descriptor: 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide, CYCLIN-DEPENDENT KINASE 9, CYCLIN-T1 Authors: Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M. Deposit date: 2012-10-02 Release date: 2013-01-09 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity. J.Med.Chem., 56, 2013
4CN2	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*TP*TP*GP*AP*CP*CP*CP*TP*TP*GP*AP*AP*DC *TP*CP*AP)-3', 5'-D(*TP*GP*AP*GP*TP*TP*CP*AP*AP*GP*GP*GP*TP*DC *AP*AP*TP)-3', ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.069 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4EC9	Crystal structure of full-length cdk9 in complex with cyclin t Descriptor: Cyclin-T1, Cyclin-dependent kinase 9 Authors: Baumli, S, Hole, A.J, Endicott, J.A. Deposit date: 2012-03-26 Release date: 2012-09-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.21 Å) Cite: The CDK9 tail determines the reaction pathway of positive transcription elongation factor b. Structure, 20, 2012
1K5K	Homonuclear 1H Nuclear Magnetic Resonance Assignment and Structural Characterization of HIV-1 Tat Mal Protein Descriptor: TAT protein Authors: Gregoire, C, Peloponese, J.M, Esquieu, D, Opi, S, Campbell, G, Solomiac, M, Lebrun, E, Lebreton, J, Loret, E.P. Deposit date: 2001-10-11 Release date: 2002-06-19 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein. Biopolymers, 62, 2001
4IEM	Human apurinic/apyrimidinic endonuclease (APE1) with product DNA and Mg2+ Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*C)-3'), DNA (5'-D(P*(3DR)P*GP*AP*TP*CP*G)-3'), ... Authors: Tsutakawa, S.E, Mol, C.D, Arvai, A.S, Tainer, J.A. Deposit date: 2012-12-13 Release date: 2013-01-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3936 Å) Cite: Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes. J.Biol.Chem., 288, 2013
4IMY	The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat Descriptor: ADENOSINE MONOPHOSPHATE, AF4/FMR2 family member 4, Cyclin-T1, ... Authors: Alber, T, Schulze-Gahmen, U. Deposit date: 2013-01-03 Release date: 2013-03-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.94 Å) Cite: The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. Elife, 2, 2013
4CN3	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Gde1SpA Response Element Descriptor: 5'-D(*CP*TP*AP*GP*TP*TP*CP*AP*AP*AP*GP*TP*TP*CP *AP*CP*A)-3', 5'-D(*TP*GP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*AP*CP *TP*AP*G)-3', RETINOIC ACID RECEPTOR RXR-ALPHA, ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4CN7	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to an idealized DR1 Response Element Descriptor: 5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP *AP*GP)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP *AP*GP)-3', CHLORIDE ION, ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4EC8	Structure of full length CDK9 in complex with cyclinT and DRB Descriptor: Cyclin-T1, Cyclin-dependent kinase 9 Authors: Baumli, S, Hole, A.J, Endicott, J.A. Deposit date: 2012-03-26 Release date: 2012-09-12 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.6 Å) Cite: The CDK9 tail determines the reaction pathway of positive transcription elongation factor b. Structure, 20, 2012
1NFI	I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX Descriptor: I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65 Authors: Jacobs, M.D, Harrison, S.C. Deposit date: 1998-08-25 Release date: 1998-11-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of an IkappaBalpha/NF-kappaB complex. Cell(Cambridge,Mass.), 95, 1998
7U50	APE1 bound to a nucleosome core particle with AP-site at SHL-6 Descriptor: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ... Authors: Weaver, T.M, Freudenthal, B.D. Deposit date: 2022-03-01 Release date: 2022-09-07 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for APE1 processing DNA damage in the nucleosome. Nat Commun, 13, 2022
8HBM	Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA Descriptor: Bile acid receptor, DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*AP*TP*GP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*TP*TP*GP*AP*CP*CP*TP*CP*G)-3'), ... Authors: Jiang, L, Chen, Y. Deposit date: 2022-10-29 Release date: 2023-06-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA. Comput Struct Biotechnol J, 21, 2023

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