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PDB: 1361 results

4V8D
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Structure analysis of ribosomal decoding (cognate tRNA-tyr complex).
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V47
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Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the EF-G.GTP state of E. coli 70S ribosome
Descriptor: 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J.
Deposit date:2003-05-06
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (12.3 Å)
Cite:Study of the structural dynamics of the E. coli 70S ribosome using real space refinement
Cell(Cambridge,Mass.), 113, 2003
4V4I
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Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements.
Descriptor: 16S SMALL SUBUNIT RIBOSOMAL RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
Authors:Korostelev, A, Trakhanov, S, Laurberg, M, Noller, H.F.
Deposit date:2007-02-15
Release date:2014-07-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
Cell(Cambridge,Mass.), 126, 2006
4V4W
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Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4V5F
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The structure of the ribosome with elongation factor G trapped in the post-translocational state
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Gao, Y.-G, Selmer, M, Dunham, C.M, Weixlbaumer, A, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-09-01
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science, 326, 2009
4V5Y
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF).
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
Deposit date:2007-06-19
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.45 Å)
Cite:Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V6M
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Structure of the ribosome-SecYE complex in the membrane environment
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 16S RIBOSOMAL RNA, ...
Authors:Frauenfeld, J, Gumbart, J, van der Sluis, E.O, Funes, S, Gartmann, M, Beatrix, B, Mielke, T, Berninghausen, O, Becker, T, Schulten, K, Beckmann, R.
Deposit date:2011-02-08
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Cryo-EM structure of the ribosome-SecYE complex in the membrane environment.
Nat.Struct.Mol.Biol., 18, 2011
4V6X
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Structure of the human 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
Deposit date:2013-02-27
Release date:2014-07-09
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
4V7S
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Crystal structure of the E. coli ribosome bound to telithromycin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
Deposit date:2010-08-05
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2547 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V8A
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The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Bulkley, D, Johnson, F.A, Steitz, T.A.
Deposit date:2011-12-05
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
J.Mol.Biol., 416, 2012
4V95
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Crystal structure of YAEJ bound to the 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A.
Deposit date:2012-01-27
Release date:2014-07-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science, 335, 2012
4V8Y
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Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex
Descriptor: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ...
Authors:Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
4V9K
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70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
Deposit date:2013-04-24
Release date:2014-07-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
4W4G
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Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M.
Deposit date:2014-08-14
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V9S
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Crystal structure of antibiotic GE82832 bound to 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
Deposit date:2013-12-05
Release date:2014-07-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V4R
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Crystal structure of the whole ribosomal complex.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-09-30
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.9 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V53
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin.
Descriptor: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
Authors:Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
Deposit date:2007-06-16
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V5L
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The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V.
Deposit date:2010-09-02
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Mechanism for Activation of GTP Hydrolysis on the Ribosome.
Science, 330, 2010
4V6D
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Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zhang, W, Dunkle, J.A, Cate, J.H.D.
Deposit date:2009-06-27
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.814 Å)
Cite:Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4V6Y
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BU of 4v6y by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V7C
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BU of 4v7c by Molmil
Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA structure)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N.
Deposit date:2013-11-20
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V7R
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Yeast 80S ribosome.
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Ben-Shem, A, Jenner, L, Yusupova, G, Yusupov, M.
Deposit date:2010-07-23
Release date:2014-07-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of the eukaryotic ribosome.
Science, 330, 2010
4V3P
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The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes
Descriptor: 18S ribosomal RNA, 26S ribosomal RNA, 40S WHEAT GERM RIBOSOME protein 4, ...
Authors:Myasnikov, A.G, Afonina, Z.A, Menetret, J.F, Shirokov, V.A, Spirin, A.S, Klaholz, B.P.
Deposit date:2014-10-20
Release date:2015-04-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (34 Å)
Cite:The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes.
Nat Commun, 5, 2014
4V8J
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Crystal structure of the bacterial ribosome ram mutation G347U.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
Deposit date:2011-12-20
Release date:2014-07-09
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V4V
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Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006

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