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PDB: 392 results

5NBD
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PglK flippase in complex with inhibitory nanobody
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Nanobody, WlaB protein
Authors:Perez, C, Pardon, E, Steyaert, J, Locher, K.P.
Deposit date:2017-03-01
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.
Sci Rep, 7, 2017
5OCH
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BU of 5och by Molmil
The crystal structure of human ABCB8 in an outward-facing state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 8, mitochondrial, ...
Authors:Faust, B, Pike, A.C.W, Shintre, C.A, Quiqley, A.M, Chu, A, Barr, A, Shrestha, L, Mukhopadhyay, S, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2017-06-30
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The crystal structure of human ABCB8 in an outward-facing state
To Be Published
5OFP
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BU of 5ofp by Molmil
Structure of the antibacterial peptide ABC transporter McjD in an apo inward occluded conformation
Descriptor: Microcin-J25 export ATP-binding/permease protein McjD
Authors:Beis, K, Choudhury, H.G.
Deposit date:2017-07-11
Release date:2017-09-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.71 Å)
Cite:Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
4AYT
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BU of 4ayt by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
7A65
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Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
Descriptor: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
4A82
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BU of 4a82 by Molmil
Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966.
Descriptor: CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
Authors:Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C.
Deposit date:2011-11-18
Release date:2012-01-11
Last modified:2024-05-08
Method:ELECTRON CRYSTALLOGRAPHY (9 Å)
Cite:The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate.
J.Biol.Chem., 286, 2011
5MKK
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BU of 5mkk by Molmil
Crystal structure of the heterodimeric ABC transporter TmrAB, a homolog of the antigen translocation complex TAP
Descriptor: Multidrug resistance ABC transporter ATP-binding and permease protein, SULFATE ION
Authors:Noell, A, Thomas, C, Tomasiak, T.M, Olieric, V, Wang, M, Diederichs, K, Stroud, R.M, Pos, K.M, Tampe, R.
Deposit date:2016-12-05
Release date:2017-01-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OFR
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BU of 5ofr by Molmil
Structure of the antibacterial peptide ABC transporter McjD in a high energy outward occluded intermediate state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
Authors:Beis, K, Bountra, K.
Deposit date:2017-07-11
Release date:2017-09-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
4KSD
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BU of 4ksd by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A, R2 protein
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.1001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSC
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BU of 4ksc by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSB
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BU of 4ksb by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZDQ
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BU of 3zdq by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL, CARDIOLIPIN, ...
Authors:Pike, A.C.W, Shintre, C.A, Krojer, T, von Delft, F, Vollmar, M, Mukhopadhyay, S, Burgess-Brown, N, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-11-30
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYX
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BU of 4ayx by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
3B5X
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BU of 3b5x by Molmil
Crystal Structure of MsbA from Vibrio cholerae
Descriptor: Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B5Z
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BU of 3b5z by Molmil
Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lipid A export ATP-binding/permease protein msbA, VANADATE ION
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4M2S
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BU of 4m2s by Molmil
Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR
Descriptor: (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A
Authors:Li, J, Jaimes, K.F, Aller, S.G.
Deposit date:2013-08-05
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Refined structures of mouse P-glycoprotein.
Protein Sci., 23, 2014
4AYW
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BU of 4ayw by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4M1M
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BU of 4m1m by Molmil
Corrected Structure of Mouse P-glycoprotein
Descriptor: MERCURY (II) ION, Multidrug resistance protein 1A
Authors:Li, J, Jaimes, K.F, Aller, S.G.
Deposit date:2013-08-03
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Refined structures of mouse P-glycoprotein.
Protein Sci., 23, 2014
3B5W
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BU of 3b5w by Molmil
Crystal Structure of Eschericia coli MsbA
Descriptor: Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.3 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B60
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BU of 3b60 by Molmil
Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form
Descriptor: Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B5Y
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BU of 3b5y by Molmil
Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP
Descriptor: Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007

223532

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