7DSK
| Overall structure of the LAT1-4F2hc bound with JX-075 | Descriptor: | (2~{S})-2-azanyl-7-(naphthalen-1-ylmethoxy)-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q. | Deposit date: | 2020-12-31 | Release date: | 2021-03-10 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7, 2021
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7DSN
| Overall structure of the LAT1-4F2hc bound with JX-119 | Descriptor: | (2~{S})-2-azanyl-7-[[2-(1,3-benzoxazol-2-yl)phenyl]methoxy]-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q. | Deposit date: | 2020-12-31 | Release date: | 2021-03-10 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7, 2021
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1HX0
| Structure of pig pancreatic alpha-amylase complexed with the "truncate" acarbose molecule (pseudotrisaccharide) | Descriptor: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ALPHA AMYLASE (PPA), ... | Authors: | Qian, M, Payan, F. | Deposit date: | 2001-01-11 | Release date: | 2001-08-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High-resolution structural analysis of an enzyme-inhibitor complex Biochemistry, 40, 2001
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7DF1
| Crystal structure of human CD98 heavy chain extracellular domain in complex with S1-F4 scFv | Descriptor: | 4F2 cell-surface antigen heavy chain, IGL c2062_light_IGKV4-1_IGKJ5, S1-F4 VH | Authors: | Liu, X, Ding, J, Sui, J, Tian, X. | Deposit date: | 2020-11-06 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | An anti-CD98 antibody displaying pH-dependent Fc-mediated tumour-specific activity against multiple cancers in CD98-humanized mice. Nat Biomed Eng, 2022
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7EPZ
| Overall structure of Erastin-bound xCT-4F2hc complex | Descriptor: | 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-04-28 | Release date: | 2022-04-06 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Res., 32, 2022
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7CMI
| The LAT2-4F2hc complex in complex with leucine | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | Authors: | Yan, R.H, Zhou, J.Y, Li, Y.N, Lei, J.L, Zhou, Q. | Deposit date: | 2020-07-27 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex. Cell Discov, 6, 2020
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7CGT
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5YKB
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5ZCC
| Crystal structure of Alpha-glucosidase in complex with maltose | Descriptor: | Alpha-glucosidase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Kato, K, Saburi, W, Yao, M. | Deposit date: | 2018-02-16 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.704 Å) | Cite: | Function and structure of GH13_31 alpha-glucosidase with high alpha-(1→4)-glucosidic linkage specificity and transglucosylation activity. FEBS Lett., 592, 2018
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5Z0U
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5ZCE
| Crystal structure of Alpha-glucosidase in complex with maltotetraose | Descriptor: | Alpha-glucosidase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Kato, K, Saburi, W, Yao, M. | Deposit date: | 2018-02-16 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.555 Å) | Cite: | Function and structure of GH13_31 alpha-glucosidase with high alpha-(1→4)-glucosidic linkage specificity and transglucosylation activity. FEBS Lett., 592, 2018
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5Z0T
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5ZCD
| Crystal structure of Alpha-glucosidase in complex with maltotriose | Descriptor: | Alpha-glucosidase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Kato, K, Saburi, W, Yao, M. | Deposit date: | 2018-02-16 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.707 Å) | Cite: | Function and structure of GH13_31 alpha-glucosidase with high alpha-(1→4)-glucosidic linkage specificity and transglucosylation activity. FEBS Lett., 592, 2018
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6AAV
| Crystal structure of alpha-glucosyl transfer enzyme, XgtA at 1.72 angstrom resolution | Descriptor: | Alpha-glucosyltransferase | Authors: | Kurumizaka, H, Arimura, Y, Kirimura, K, Watanabe, R. | Deposit date: | 2018-07-19 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal structure of alpha-glucosyl transfer enzyme XgtA from Xanthomonas campestris WU-9701. Biochem.Biophys.Res.Commun., 526, 2020
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6AG0
| The X-ray Crystallographic Structure of Maltooligosaccharide-forming Amylase from Bacillus stearothermophilus STB04 | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-amylase, CALCIUM ION | Authors: | Li, Z.F, Li, Y.L, Ban, X.F, Zhang, C.Y, Jin, T.C, Xie, X.F, Gu, Z.B, Li, C.M. | Deposit date: | 2018-08-09 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a maltooligosaccharide-forming amylase from Bacillus stearothermophilus STB04. Int.J.Biol.Macromol., 138, 2019
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5BRQ
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6L2H
| CGTase mutant-Y167H | Descriptor: | Alpha-cyclodextrin glucanotransferase, CALCIUM ION | Authors: | Fan, T.W, Hou, A.Q, Chao, Y.P, Sun, Y. | Deposit date: | 2019-10-03 | Release date: | 2019-10-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Structure basis of a mutant a-CGTase tyrosine167histidine from Bacillus sp. 602-1 with enhanced a-CD production To Be Published
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5BRP
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5CLW
| Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose | Descriptor: | 1,4-alpha-glucan-branching enzyme, SODIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Krojer, T, Froese, D.S, Goubin, S, Strain-Damerell, C, Mahajan, P, Burgess-Brown, N, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Yue, W, Structural Genomics Consortium (SGC) | Deposit date: | 2015-07-16 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose To be published
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6LID
| Heteromeric amino acid transporter b0,+AT-rBAT complex | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yan, R.H, Li, Y.N, Lei, J.L, Zhou, Q. | Deposit date: | 2019-12-10 | Release date: | 2020-04-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT. Sci Adv, 6, 2020
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3EDF
| Structural base for cyclodextrin hydrolysis | Descriptor: | CALCIUM ION, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), Cyclomaltodextrinase, ... | Authors: | Buedenbender, S, Schulz, G.E. | Deposit date: | 2008-09-03 | Release date: | 2009-03-03 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural base for enzymatic cyclodextrin hydrolysis J.Mol.Biol., 385, 2009
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6LI9
| Heteromeric amino acid transporter b0,+AT-rBAT complex bound with Arginine | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, ... | Authors: | Yan, R.H, Li, Y.N, Lei, J.L, Zhou, Q. | Deposit date: | 2019-12-10 | Release date: | 2020-04-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT. Sci Adv, 6, 2020
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5GTW
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3EDJ
| Structural base for cyclodextrin hydrolysis | Descriptor: | CALCIUM ION, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cyclomaltodextrinase, ... | Authors: | Buedenbender, S, Schulz, G.E. | Deposit date: | 2008-09-03 | Release date: | 2009-03-03 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural base for enzymatic cyclodextrin hydrolysis J.Mol.Biol., 385, 2009
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5GQU
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